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Akademický článek

Jmjd3 mediates blood–spinal cord barrier disruption after spinal cord injury by regulating MMP-3 and MMP-9 expressions

Autor: Jee Y. Lee, Won H. Na, Hae Y. Choi, Kwang H. Lee, Bong G. Ju, Tae Y. Yune

Publikováno v: Neurobiology of Disease, Vol 95, Iss , Pp 66-81 (2016)

The disruption of the blood–spinal cord barrier (BSCB) by matrix metalloprotease (MMP) activation is a detrimental event that leads to blood cell infiltration, inflammation, and apoptosis, thereby contributing to permanent neurological disability a

Externí odkaz: https://doaj.org/article/827c9d11baa14ff98d4458e5ce50f186

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Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

Autor: Jee Y, Lee, Hwang S, Kim, Hye Y, Choi, Tae H, Oh, Bong G, Ju, Tae Y, Yune

Publikováno v: Journal of neurochemistry. 121(5)

The disruption of blood-spinal cord barrier (BSCB) after spinal cord injury (SCI) elicits an intensive local inflammation by the infiltration of blood cells such as neutrophils and macrophages, leading to cell death and permanent neurological disabil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8996bb795b30061bc5c9391720987e37
https://pubmed.ncbi.nlm.nih.gov/22409448

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