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pro vyhledávání: '"Bong F. Sanpablo"'
Autor:
Ramesha Chakk S, Jin-Hai Wang, Russell Stephen Stabler, Paul Weller, Bong F. Sanpablo, Armando G. Villaseñor, Campbell Jeffrey Allen, Tara Mirzadegan, Viola Bordunov, Chris Allen Broka, Patricia Takahara, James M. Kress, Michelle F. Browner, Keith A. M. Walker, Mary Welch
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:4741-4745
The introduction of 3-arylmethyl, 3-aryloxy and 3-arylthio moieties into a 6-methylsulfonylindole framework using rational drug design led to potent, selective COX-2 inhibitors having efficacy in a rat carrageenan air pouch model. Incorporation of a