Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bone Neoplasms/metabolism"'
Autor:
Jane E. Aubin, Geoffrey Vargas, Edith Bonnelye, Sophie Vacher, Marie Brevet, Pascal Reboul, M Filipits, Ivan Bièche, C Boyault, W Jacot, Lamia Bouazza, Sandra Geraci, Keltouma Driouch, Francesco Pantano, Michael Gnant, Catherine Alix-Panabières, M Gervais, Laure Cayrefourcq, Philippe Clézardin, M Bouchet, M Mazel, Martine Croset, Claire Benetollo, C Kan, Martine Duterque-Coquillaud
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2019, 38 (7), pp.950-964. ⟨10.1038/s41388-018-0579-3 ⟩
Oncogene, Nature Publishing Group, 2019, 38 (7), pp.950-964. ⟨10.1038/s41388-018-0579-3⟩
Oncogene, 2019, 38 (7), pp.950-964. ⟨10.1038/s41388-018-0579-3⟩
Oncogene, Nature Publishing Group, 2019, 38 (7), pp.950-964. ⟨10.1038/s41388-018-0579-3 ⟩
Oncogene, Nature Publishing Group, 2019, 38 (7), pp.950-964. ⟨10.1038/s41388-018-0579-3⟩
Oncogene, 2019, 38 (7), pp.950-964. ⟨10.1038/s41388-018-0579-3⟩
International audience; Bone is the most common metastatic site for breast cancer. Estrogen-related-receptor alpha (ERRα) has been implicated in cancer cell invasiveness. Here, we established that ERRα promotes spontaneous metastatic dissemination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673afe46894df907867170c048c800d7
http://hdl.handle.net/20.500.12210/55264
http://hdl.handle.net/20.500.12210/55264
Autor:
Rachel Deplus, Martine Duterque-Coquillaud, Anne Flourens, Edith Bonnelye, Nathalie Vanpouille, Tian V. Tian, Philippe Clézardin, Anais Fradet, Carine Delliaux, Xavier Leroy, Yvan de Launoit, Mathilde Bouchet, Arnauld Villers
Publikováno v:
Cancer Letters
Cancer Letters, Elsevier, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, Elsevier, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
Cancer Letters, 2018, 438, pp.32-43. ⟨10.1016/j.canlet.2018.08.027⟩
International audience; Abstract : Prostate cancers have a strong propensity to metastasize to bone and promote osteoblastic lesions. TMPRSS2:ERG is the most frequent gene rearrangement identified in prostate cancer, but whether it is involved in pro
Autor:
Roberta Mazzone, Piero Picci, Katia Scotlandi, Michela Pasello, Patrizia Nanni, Giordano Nicoletti, Maria Cristina Manara, Antonello Mai, Clara Guerzoni, Camilla Cristalli, Pier Luigi Lollini, Lorena Landuzzi, Sergio Valente, Giulia Stazi, Paola B. Arimondo, Clemens Zwergel
Publikováno v:
Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
Molecular Cancer Therapeutics, American Association for Cancer Research, 2018, 17 (9), pp.1881-1892. ⟨10.1158/1535-7163.MCT-17-0818⟩
The identification of new therapeutic strategies against osteosarcoma, the most common primary bone tumor, continues to be a primary goal to improve the outcomes of patients refractory to conventional chemotherapy. Osteosarcoma originates from the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55d5482d55dc2ed43ad6818ec4cbf60
https://hal.archives-ouvertes.fr/hal-02383680
https://hal.archives-ouvertes.fr/hal-02383680
Autor:
Stephen P. Jackson, Mareike Herzog, Alejandra Bruna, Luca Pellegrini, Violeta Serra, Mark J. O'Connor, Zhongwu Lai, Chloé Lescale, Jacqueline J.L. Jacobs, Fengtang Yang, Jonathan Lam, Matylda Sczaniecka-Clift, Abigail Shea, Carlos Caldas, Matthias Ostermaier, Gabriel Balmus, Julia Coates, Wenming Wei, Inge de Krijger, Yaron Galanty, Mukerrem Demir, Ludovic Deriano, Petra Beli, Domenic Pilger, Harveer Dev, Rimma Belotserkovskaya, Alistair Martin, Beiyuan Fu, Ting-Wei Will Chiang, Qian Wu
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
Nature Cell Biology, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
International audience; BRCA1 deficiencies cause breast, ovarian, prostate and other cancers, and render tumours hypersensitive to poly(ADP-ribose) polymerase (PARP) inhibitors. To understand the resistance mechanisms, we conducted whole-genome CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c03882fb1aad0056e71d15c34e8ed4
https://www.repository.cam.ac.uk/handle/1810/282947
https://www.repository.cam.ac.uk/handle/1810/282947
Autor:
Ivan Stamenkovic, Miguel Rivera, Angela Volorio, Sowmya Iyer, Liliane C. Broye, Nicolo Riggi, Gaylor Boulay
Publikováno v:
Genes & development, vol. 32, no. 15-16, pp. 1008-1019
Various types of repetitive sequences are dysregulated in cancer. In Ewing sarcoma, the oncogenic fusion protein EWS-FLI1 induces chromatin features typical of active enhancers at GGAA microsatellite repeats, but the function of these sites has not b
Autor:
Anne Flourens, Carine Delliaux, Yvan de Launoit, Xavier Leroy, Rachel Deplus, Martine Duterque-Coquillaud, Nathalie Marchand, Nathalie Vanpouille
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2017, 8 (7), pp.11827-11840. ⟨10.18632/oncotarget.14399⟩
Oncotarget, 2017, 8 (7), pp.11827-11840. ⟨10.18632/oncotarget.14399⟩
Oncotarget, 8 (7
Oncotarget, Impact journals, 2017, 8 (7), pp.11827-11840. ⟨10.18632/oncotarget.14399⟩
Oncotarget, 2017, 8 (7), pp.11827-11840. ⟨10.18632/oncotarget.14399⟩
Oncotarget, 8 (7
Bone metastasis is the major deleterious event in prostate cancer (PCa). TMPRSS2-ERG fusion is one of the most common chromosomic rearrangements in PCa. However, its implication in bone metastasis development is still unclear. Since bone metastasis s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6842a4a21bd05145fce04e57a3617d
https://hal.archives-ouvertes.fr/hal-02391621/file/TMPRSS2-ERG_fusion_promotes_prostate.pdf
https://hal.archives-ouvertes.fr/hal-02391621/file/TMPRSS2-ERG_fusion_promotes_prostate.pdf
Autor:
Claire Benetollo, Edith Bonnelye, Vincenzo Castronovo, Jennifer Rieusset, Thomas J. Rosol, Mathilde Bouchet, Anais Fradet, Akeila Bellahcene, Lamia Bouazza, Carine Delliaux, Philippe Clézardin, Martine Duterque-Coquillaud, Martine Croset, Casina Kan, Francesco Pantano, Xavier Leroy, Manon Gervais, Jane E. Aubin, Geoffrey Vargas, Yohann Bala
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2016, 7 (47), pp.77071-77086. ⟨10.18632/oncotarget.12787⟩
Oncotarget, 2016, 7 (47), pp.77071-77086. ⟨10.18632/oncotarget.12787⟩
Oncotarget, Impact journals, 2016, 7 (47), pp.77071-77086. ⟨10.18632/oncotarget.12787⟩
Oncotarget, 2016, 7 (47), pp.77071-77086. ⟨10.18632/oncotarget.12787⟩
International audience; Bone metastases are one of the main complications of prostate cancer and they are incurable. We investigated whether and how estrogen receptor-related receptor alpha (ERRalpha) is involved in bone tumor progression associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c51bc67b6222c2f5b71c8a281298a9
Autor:
Nicolo Riggi, Anoop P. Patel, Martin J. Aryee, Vishal Thapar, Gaylor Boulay, Aurélie Formey, G. Petur Nielsen, Ivan Stamenkovic, Shawn M. Gillespie, Edward B. Cook, Nikki E. Rossetti, Melissa Gymrek, Mario L. Suvà, Birgit Knoechel, David T. Ting, Francis J. Hornicek, Bradley E. Bernstein, Esther Rheinbay, Vikram Deshpande, Wannaporn E. Boonseng, Ozgur Oksuz, Miguel Rivera
Publikováno v:
Cancer cell, vol. 26, no. 5, pp. 668-681
SummaryThe aberrant transcription factor EWS-FLI1 drives Ewing sarcoma, but its molecular function is not completely understood. We find that EWS-FLI1 reprograms gene regulatory circuits in Ewing sarcoma by directly inducing or repressing enhancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27644e8c251df925d6e8729c03419ab
https://europepmc.org/articles/PMC4492343/
https://europepmc.org/articles/PMC4492343/
Autor:
Speciale G, Giovanni Tuccari, Antonio Ieni, Michele Attilio Rosa, Valeria Barresi, Maddalena Grosso
By immunohistochemistry, lactoferrin (LF) has been extensively investigated in human neoplastic tissues; moreover, LF is able to promote bone growth in a murine model. Until now, no systematic studies on human osteocartilagineous fetal samples have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509a4686d11e4a55c87cbe0d23d09b4e
http://hdl.handle.net/11570/1908357
http://hdl.handle.net/11570/1908357
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