Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Bone Marrow/metabolism"'
Publikováno v:
International journal of molecular sciences. 23(18)
Acute myeloid leukemia (AML) is a myeloid malignancy that is characterized by the accumulation of leukemic blast cells, which originate from hematopoietic stem cells that have undergone leukemic transformation and/or are more mature progenitors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b03ac82968121cfee739d663667128
https://doi.org/10.3390/ijms231810529
https://doi.org/10.3390/ijms231810529
Autor:
Christopher Hine, J. Humberto Treviño-Villarreal, Pedro Mejia, Alban Longchamp, Lear E. Brace, Eylul Harputlugil, Sarah J. Mitchell, Jie Yang, Yihong Guan, Jaroslaw P. Maciejewski, Babal K. Jha, James R. Mitchell
Publikováno v:
Nutrients, 14 (7)
Nutrients; Volume 14; Issue 7; Pages: 1529
Nutrients, vol. 14, no. 7, pp. 1529
Nutrients; Volume 14; Issue 7; Pages: 1529
Nutrients, vol. 14, no. 7, pp. 1529
Radiation therapy damages and depletes total bone marrow (BM) cellularity, compromising safety and limiting effective dosing. Aging also strains total BM and BM hematopoietic stem and progenitor cell (HSPC) renewal and function, resulting in multi-sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437dca448f0364d11ac1e9f912b6ebf7
https://hdl.handle.net/20.500.11850/542345
https://hdl.handle.net/20.500.11850/542345
Autor:
Davide Rossi, Rahel Schwotzer, Raphael Heimgartner, Andreas J. Flammer, Georg Stussi, Bernhard Gerber, Guido Ghilardi, Erika Lerch, Christine Waibel, Harald Seeger, Clemens Caspar, Stefanie Pederiva, Thomas Fehr, Elena Bianchi, Markus G. Manz, Sofie Brouwers
Publikováno v:
Hematological Oncology. 37:595-600
Daratumumab, an anti-CD38 antibody, is effective in AL amyloidosis with low tumor burden. Data of daratumumab treatment in patients with AL amyloidosis but high tumor burden (≥10% bone marrow plasma cells) are limited. We report retrospective data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afce2e4f761edbd1d13b6d39b85360df
https://doi.org/10.1002/hon.2677
https://doi.org/10.1002/hon.2677
Autor:
Nicola Vannini, Caroline Monnard, Mukul Girotra, Serge Rezzi, George Coukos, Federico Sizzano, Tobias Konz, Laurence Goulet, Jean-Philippe Godin
Publikováno v:
International journal of molecular sciences, vol. 21, no. 17, pp. 6444
International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6444, p 6444 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 17
International Journal of Molecular Sciences, Vol 21, Iss 6444, p 6444 (2020)
Steady hematopoiesis is essential for lifelong production of all mature blood cells. Hematopoietic stem and progenitor cells (HSPCs) found in the bone marrow ensure hematopoietic homeostasis in an organism. Failure of this complex process, which invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5f0b56509217152f9bd961023cfa2e
https://serval.unil.ch/resource/serval:BIB_477EEDC014A0.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_477EEDC014A0.P001/REF.pdf
Autor:
Bente L. Langdahl, Thomas Kjaer, Steen B. Pedersen, Torben Harsløf, Niklas Rye Jørgensen, Marie Juul Ornstrup
Publikováno v:
Ornstrup, M J, Kjær, T N, Harsløf, T, Jørgensen, N R, Pedersen, S B & Langdahl, B L 2018, ' Comparison of bone turnover markers in peripheral blood and bone marrow aspirate ', Bone, vol. 116, pp. 315-320 . https://doi.org/10.1016/j.bone.2018.08.023
BACKGROUND: Bone remodeling takes place in the bone marrow environment. We investigated if levels of bone turnover markers (BTMs) differ between bone marrow and peripheral blood, if the bone marrow is an independent compartment, and how well the meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8f8547d70babee8b8a8fd054994088
https://doi.org/10.1016/j.bone.2018.08.023
https://doi.org/10.1016/j.bone.2018.08.023
Autor:
Ellen-Margrethe Hauge, Erik Fink Eriksen, Ingvild Kristine Blom-Høgestøl, Cathrine Brunborg, Jon Kristinsson, Hanne L. Gulseth, Tom Mala
Publikováno v:
Blom-Høgestøl, I K, Mala, T, Kristinsson, J A, Hauge, E M, Brunborg, C, Gulseth, H L & Eriksen, E F 2019, ' Changes in Bone Marrow Adipose Tissue One Year After Roux-en-Y Gastric Bypass : A Prospective Cohort Study ', Journal of Bone and Mineral Research, vol. 34, no. 10, pp. 1815-1823 . https://doi.org/10.1002/jbmr.3814
Journal of Bone and Mineral Research
Journal of Bone and Mineral Research
Bone marrow adipose tissue (BMAT) has been postulated to mediate skeletal fragility in type 2 diabetes (T2D) and obesity. Roux-en-Y gastric bypass (RYGB) induces a substantial weight loss and resolution of comorbidities. However, the procedure induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87f3b91092435e7ffc2331c2c1d70a9
https://pure.au.dk/ws/files/198449601/jbmr.3814.pdf
https://pure.au.dk/ws/files/198449601/jbmr.3814.pdf
Publikováno v:
Hematology (Amsterdam, Netherlands). 24(1)
OBJECTIVES: The diagnosis of myelodysplastic syndrome (MDS) is not always straightforward in the absence of objective markers such as ringed sideroblasts, an excess of blasts or clonal cytogenetic abnormalities. Moreover, the lack of specificity of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c820bd0c05baa9c7ddede7d61771b8
https://pubmed.ncbi.nlm.nih.gov/30334700
https://pubmed.ncbi.nlm.nih.gov/30334700
Autor:
Dirk H. Busch, Jan Rozman, Robert Brommage, Helmut Fuchs, Raffi Bekeredjian, Lillian Garrett, Sabine M. Hölter, Anton Wellstein, Julia Calzada-Wack, Holger Maier, T. Klopstock, Ralph Steinkamp, Yong Gu Lee, Johannes Beckers, Marion Horsch, Patrick James Beck, Martin Hrabé de Angelis, Khalid Garman, Carsten B. Schmidt-Weber, Annemarie Zimprich, Claudia Stoeger, Marcel O. Schmidt, L. Becker, Eckhard Wolf, Thure Adler, Jochen Graw, Chong Zuo, Ildiko Racz, Irina Treise, Andreas Zimmer, Alexandra Vernaleken, Juan Antonio Aguilar-Pimentel, Wolfgang Hans, Wolfgang Wurst, Mingjun Tan, Stefanie Leuchtenberger, Christoph Lengger, Martin Klingenspor, Patricia da Silva-Buttkus, Elena Tassi, Anna T. Riegel, Valerie Gailus-Durner, Birgit Rathkolb, Manuela A. Östereicher, Markus Ollert, Kristin Moreth, Frauke Neff, Oana V. Amarie
Publikováno v:
J. Invest. Dermatol. 138, 179-188 (2018)
Schmidt, M O, Garman, K A, Lee, Y G, Zuo, C, Beck, P J, Tan, M, Aguilar-Pimentel, J A, Ollert, M, Schmidt-Weber, C, Fuchs, H, Gailus-Durner, V, Hrabe de Angelis, M, Tassi, E, Riegel, A T, Wellstein, A & German Mouse Clinic Consortium 2018, ' The Role of Fibroblast Growth Factor Binding Protein 1 in Skin Carcinogenesis and Inflammation ', Journal of Investigative Dermatology, vol. 138, no. 1, pp. 179-188 . https://doi.org/10.1016/j.jid.2017.07.847
Schmidt, M O, Garman, K A, Lee, Y G, Zuo, C, Beck, P J, Tan, M, Aguilar-Pimentel, J A, Ollert, M, Schmidt-Weber, C, Fuchs, H, Gailus-Durner, V, Hrabe de Angelis, M, Tassi, E, Riegel, A T, Wellstein, A & German Mouse Clinic Consortium 2018, ' The Role of Fibroblast Growth Factor Binding Protein 1 in Skin Carcinogenesis and Inflammation ', Journal of Investigative Dermatology, vol. 138, no. 1, pp. 179-188 . https://doi.org/10.1016/j.jid.2017.07.847
Fibroblast growth factor-binding protein 1 (FGFBP1) is a secreted chaperone that mobilizes paracrine-acting FGFs, stored in the extracellular matrix, and presents them to their cognate receptors. FGFBP1 enhances FGF signaling including angiogenesis d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef892b21438e575f4ff4729d8cf2a25
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=51790
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=51790
Autor:
Anne Wilson, He Fu, Mariano Schiffrin, Carine Winkler, Meriem Koufany, Jean-Yves Jouzeau, Nicolas Bonnet, Federica Gilardi, François Renevey, Sanjiv A. Luther, David Moulin, Béatrice Desvergne
Publikováno v:
Frontiers in Immunology, Vol. 9, No Art. 2573 (2018)
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2018, 9, pp.2573. ⟨10.3389/fimmu.2018.02573⟩
Frontiers in immunology, vol. 9, pp. 2573
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology, Frontiers, 2018, 9, pp.2573. ⟨10.3389/fimmu.2018.02573⟩
Frontiers in immunology, vol. 9, pp. 2573
Adult hematopoiesis takes place in the perivascular zone of the bone cavity, where endothelial cells, mesenchymal stromal/stem cells and their derivatives such as osteoblasts are key components of bone marrow (BM) niches. Defining the contribution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf48045a873f472936d5f9184e31b5d0
https://archive-ouverte.unige.ch/unige:112931
https://archive-ouverte.unige.ch/unige:112931
Autor:
Eline Menu, Els Van Valckenborgh, Nathan De Beule, Karin Vanderkerken, Hendrik De Raeve, Helena Eriksson, Alboukadel Kassambara, Ken Maes, Elke De Bruyne, Karel Fostier, Roy Heusschen, Dirk Hose, Jérôme Moreaux, Kim De Veirman
Publikováno v:
Cancer immunology research. 5(10)
Dysregulated expression of S100 protein family members is associated with cancer proliferation, invasion, angiogenesis, and inflammation. S100A9 induces myeloid-derived suppressor cell (MDSC) accumulation and activity. MDSCs, immunosuppressive cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8286b00699d03648115eccc4a164f7
https://pubmed.ncbi.nlm.nih.gov/28903971
https://pubmed.ncbi.nlm.nih.gov/28903971