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NOX2 decoy peptides disrupt trauma-mediated neutrophil immunosuppression and protect against lethal peritonitis

Autor: Husain, Maroof, Becker, Eugene J., Jr., Bone, Nathaniel B., Schmitt, Amy, Pittet, Jean-Francois, Zmijewski, Jaroslaw W.

Publikováno v: In Redox Biology September 2020 36

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AMPK activates Parkin independent autophagy and improves post sepsis immune defense against secondary bacterial lung infections.

Autor: Bone, Nathaniel B.¹, Becker, Eugene J.¹, Husain, Maroof¹, Jiang, Shaoning¹, Zmijewska, Anna A.², Park, Dae-Won¹, Chacko, Balu³, Darley-Usmar, Victor³, Grégoire, Murielle⁴, Tadie, Jean-Marc⁴, Thannickal, Victor J.¹, Zmijewski, Jaroslaw W.^1,5 zmijewsk@uab.edu

Publikováno v: Scientific Reports. 6/11/2021, Vol. 11 Issue 1, p1-15. 15p.

HMGB1 induces neutrophil dysfunction in experimental sepsis and in patients who survive septic shock

Autor: Grégoire, Murielle, Tadié, Jean-Marc, Uhel, Fabrice, Gacouin, Arnaud, Piau, Caroline, Bone, Nathaniel, Le Tulzo, Yves, Abraham, Edward, Tarte, Karin, Zmijewski, Jaroslaw W.

Publikováno v: Journal of Leukocyte Biology
Journal of Leukocyte Biology, Society for Leukocyte Biology, 2017, 101 (6), pp.1281-1287. ⟨10.1189/jlb.5HI0316-128RR⟩
Journal of Leukocyte Biology, 2017, 101 (6), pp.1281-1287. ⟨10.1189/jlb.5HI0316-128RR⟩

International audience; Sepsis is accompanied by the initial activation of proinflammatory pathways and long-lasting immunosuppression that appears to contribute to late-occurring mortality. Although high-mobility group box 1 (HMGB1) is involved in m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d561e1d4cef28e8e97af9fa71dcaac5b
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01533343/document