Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Bonan, Chen"'
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103535- (2024)
Hereditary spastic paraplegia (HSP) is a rare neurodegenerative disorder with the predominant clinical manifestation of spasticity in the lower extremities. Patients with HSP experience spastic paralysis in both lower limbs, leading to progressive wa
Externí odkaz:
https://doaj.org/article/3f055483659e446ca544118b85788099
Autor:
Guoming Chen, Qing Ren, Zilan Zhong, Qianfan Li, Zhiqiang Huang, Cheng Zhang, Hongchao Yuan, Zixin Feng, Bonan Chen, Ning Wang, Yibin Feng
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The intricate interplay between the gut microbiome and colorectal cancer (CRC) presents novel avenues for early diagnosis and prognosis, crucial for improving patient outcomes. This comprehensive review synthesizes current findings on the gut microbi
Externí odkaz:
https://doaj.org/article/7a27afc90d244b1b801963d274f5c9c5
Autor:
Xiaoqing Guan, Yichao Wang, Wenkai Yu, Yong Wei, Yang Lu, Enyu Dai, Xiaowu Dong, Bing Zhao, Can Hu, Li Yuan, Xin Luan, Kai Miao, Bonan Chen, Xiang‐Dong Cheng, Weidong Zhang, Jiang‐Jiang Qin
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Gastric cancer (GC) presents a formidable global health challenge, and conventional therapies face efficacy limitations. Ubiquitin‐specific protease 7 (USP7) plays pivotal roles in GC development, immune response, and chemo‐resistance, m
Externí odkaz:
https://doaj.org/article/309f94baa7be42939e0ccca5ef7af44d
Autor:
Bonan Chen, Peiyao Yu, Wai Nok Chan, Fuda Xie, Yigan Zhang, Li Liang, Kam Tong Leung, Kwok Wai Lo, Jun Yu, Gary M. K. Tse, Wei Kang, Ka Fai To
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-41 (2024)
Abstract Zinc metabolism at the cellular level is critical for many biological processes in the body. A key observation is the disruption of cellular homeostasis, often coinciding with disease progression. As an essential factor in maintaining cellul
Externí odkaz:
https://doaj.org/article/09e92dfd5d834ba09b5bb3234a545c80
Autor:
Alvin Ho-Kwan Cheung, Kit-Yee Wong, Xiaoli Liu, Fenfen Ji, Chris Ho-Lam Hui, Yihan Zhang, Johnny Sheung-Him Kwan, Bonan Chen, Yujuan Dong, Raymond Wai-Ming Lung, Jun Yu, Kwok Wai Lo, Chi Chun Wong, Wei Kang, Ka-Fai To
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-14 (2023)
Abstract MLK4, a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family, has been implicated in cancer progression. However, its role in lung adenocarcinoma has not been characterized. Here, we showed that MLK4 was overexpressed
Externí odkaz:
https://doaj.org/article/1fab759148bb485a803a9fe5b39656cf
Autor:
Bonan Chen, Wai Nok Chan, Fuda Xie, Chun Wai Mui, Xiaoli Liu, Alvin H. K. Cheung, Raymond W. M. Lung, Chit Chow, Zhenhua Zhang, Canbin Fang, Peiyao Yu, Shihua Shi, Shikun Zhou, Guoming Chen, Zhangding Wang, Shouyu Wang, Xiaofan Ding, Bing Huang, Li Liang, Yujuan Dong, Chi Chun Wong, William K. K. Wu, Alfred S. L. Cheng, Nathalie Wong, Jun Yu, Kwok Wai Lo, Gary M. K. Tse, Wei Kang, Ka Fai To
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 12, Pp n/a-n/a (2023)
Abstract Background Cancer‐associated fibroblasts (CAFs), integral to the tumour microenvironment, are pivotal in cancer progression, exhibiting either pro‐tumourigenic or anti‐tumourigenic functions. Their inherent phenotypic and functional di
Externí odkaz:
https://doaj.org/article/9cd923a1d35b477fa1d0c64190bf7e15
Autor:
Bonan Chen, Xiaoli Liu, Peiyao Yu, Fuda Xie, Johnny S. H. Kwan, Wai Nok Chan, Canbin Fang, Jinglin Zhang, Alvin H. K. Cheung, Chit Chow, Gloria W. M. Leung, Kam Tong Leung, Shihua Shi, Bin Zhang, Shouyu Wang, Dazhi Xu, Kaili Fu, Chi Chun Wong, William K. K. Wu, Michael W. Y. Chan, Patrick M. K. Tang, Chi Man Tsang, Kwok Wai Lo, Gary M. K. Tse, Jun Yu, Ka Fai To, Wei Kang
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Abstract Background Gastric cancer (GC) is one of the most common tumours in East Asia countries and is associated with Helicobacter pylori infection. H. pylori utilizes virulence factors, CagA and VacA, to up‐regulate pro‐inflammatory cytokines
Externí odkaz:
https://doaj.org/article/7bfa61a822b64b09a39959da5d928f18
Autor:
Siying Hu, Dan Luo, Qikui Zhu, Jie Pan, Bonan Chen, Michael Furian, Harsh Vivek Harkare, Shoukai Sun, Adel Fansa, Xiaoping Wu, Baili Yu, Tianhong Ma, Fei Wang, Shihua Shi
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background and aims: Chinese herbal medicine (CHM) was used to prevent and treat coronavirus disease 2019 (COVID-19) in clinical practices. Many studies have demonstrated that the combination of CHM and Western medicine can be more effective in treat
Externí odkaz:
https://doaj.org/article/afe881acc82247f09b3da4736eceed64
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 3, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/1d8ccae8dff047db8893ef0085f000a1
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 3, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/13735357856741d5a24d3aecc570e273