Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bona Linke"'
Autor:
Bona Linke, Yannick Schreiber, Bettina Picard-Willems, Patrick Slattery, Rolf M. Nüsing, Sebastian Harder, Gerd Geisslinger, Klaus Scholich
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Platelets are well known for their role in hemostasis and are also increasingly recognized for their roles in the innate immune system during inflammation and their regulation of macrophage activation. Here, we aimed to study the influence of platele
Externí odkaz:
https://doaj.org/article/1f8495722a3c4c3a94bc72fd7164db46
Autor:
Bona Linke, Sonja Luckhardt, Carmen Feinweber, Hiromi Shiratori, Andreas Weigert, Eduard Resch, Gerd Geisslinger, Michael J. Parnham
Publikováno v:
Molecular Immunology. 88:58-68
Macrophages (Mφ) undergo activation to pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes in response to pathophysiologic stimuli and dysregulation of the M1-M2 balance is often associated with diseases. Therefore, studying mechanisms of mac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d22391bd73033969f9e467fe9bd5f4
https://doi.org/10.1016/j.molimm.2017.05.027
https://doi.org/10.1016/j.molimm.2017.05.027
Autor:
Stefanie Frölich, Gerd Geisslinger, Sascha Meyer dos Santos, Nerea Ferreirós, Dominique Thomas, Bona Linke, Domenico Del Turco, Neda Tarighi, Klaus Scholich, Jing Suo, Marco Sisignano, Thomas Deller, Rolf M. Nüsing, Bernhard Nieswandt, Sandra Pierre, Natasja deBruin, David Stegner
Publikováno v:
Journal of Investigative Dermatology. 137:686-695
Platelets are well known for their role in hemostasis but are also increasingly recognized for their supporting role in innate immune responses. Here, we studied the role of platelets in the development of peripheral inflammation and found that plate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b38c6ce57eaa33b1b5f405b9c3192c
https://doi.org/10.1016/j.jid.2016.09.036
https://doi.org/10.1016/j.jid.2016.09.036
Neutrophils mediate edema formation but not mechanical allodynia during zymosan-induced inflammation
Autor:
Sascha Meyer dos Santos, Klaus Scholich, Sandra Pierre, Bona Linke, Bernhard Nieswandt, David Stegner, Dong Dong Zhang, Jing Suo, Cécile V. Denis, Gerd Geisslinger
Publikováno v:
Journal of Leukocyte Biology. 96:133-142
Inflammatory pain is based on stimulation and sensitization of peripheral endings of sensory neurons (nociceptors) by pronociceptive mediators. These mediators can be released by resident cells, as well as invading immune cells. Although neutrophils
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719a40c7f0cb325ed0838f972bceabd6
https://doi.org/10.1189/jlb.3a1213-628r
https://doi.org/10.1189/jlb.3a1213-628r
Autor:
Sandra Pierre, Wiebke Becker, Gerd Geisslinger, Christian Brenneis, Ovidiu Coste, Helmut Schmidt, Wei Gao, Klaus Scholich, Christian Maeurer, Bona Linke
Publikováno v:
Journal of Biological Chemistry. 283:32442-32451
Sphingosine 1-Phosphate (S1P) modulates various cellular functions such as apoptosis, cell differentiation, and migration. Although S1P is an abundant signaling molecule in the central nervous system, very little is known about its influence on neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf2351abfdce1e82c86f74f9c7b4fbe
https://doi.org/10.1074/jbc.m806410200
https://doi.org/10.1074/jbc.m806410200
Autor:
Nerea Ferreirós, Klaus Scholich, Dong Dong Zhang, Marina Henke, Aleksandra Zivkovic, Bona Linke, Gerd Geisslinger, Yannick Schreiber, Jing Suo, Holger Stark
Publikováno v:
Biological chemistry. 396(6-7)
FTY720 (fingolimod) is, after its phosphorylation by sphingosine kinase (SPHK) 2, a potent, non-selective sphingosine-1-phosphate (S1P) receptor agonist. FTY720 has been shown to reduce the nociceptive behavior in the paclitaxel model for chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc91968b59cefac5d6a120d7ccae86d8
https://pubmed.ncbi.nlm.nih.gov/25720064
https://pubmed.ncbi.nlm.nih.gov/25720064
Autor:
S. Meyer dos Santos, Nadejda Monsefi, K. Blankenbach, Bona Linke, Klaus Scholich, Sebastian Harder, Hans Deckmyn, M. Keese, Karen Nelson, A. Dörr
Publikováno v:
Thrombosis and haemostasis. 114(2)
SummaryEndothelial chemokine CXC motif ligand 16 (CXCL16) expression is associated with atherosclerosis, while platelets, particularly those attaching to atherosclerotic plaque, contribute to all stages of athero-sclerotic disease. This investigation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f0d255b1238b5bdef226e7f7a340f9
https://pubmed.ncbi.nlm.nih.gov/25904061
https://pubmed.ncbi.nlm.nih.gov/25904061
Autor:
Yannick Schreiber, Nerea Ferreiros-Bouzas, Carlo Angioni, Bona Linke, Klaus Scholich, Claus-Dieter Schuh, Dong Dong Zhang, Marina Henke, Rolf M. Nüsing, Gerd Geisslinger, Sandra Pierre, Christian Brenneis
Publikováno v:
Anesthesiology. 120(2)
Background: Prostacyclin (PGI2) is known to be an important mediator of peripheral pain sensation (nociception) whereas little is known about its role in central sensitization. Methods: The levels of the stable PGI2-metabolite 6-keto-prostaglandin F1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a113824544f34812305b34a0c6d00a97
https://pubmed.ncbi.nlm.nih.gov/23969560
https://pubmed.ncbi.nlm.nih.gov/23969560
Autor:
Nerea Ferreiros-Bouzas, Carlo Angioni, Yannick Schreiber, Judith Fuchs, Jing Suo, Bona Linke, Sandra Pierre, Klaus Scholich, Dong Dong Zhang, Gerd Geisslinger, Marina Henke, Ovidiu Coste
Publikováno v:
Prostaglandinsother lipid mediators. 99(1-2)
Sphingosine-1-phosphate (S1P) is generated through phosphorylation of sphingosine by two sphingosine kinases (SPHK-1 and -2). As extra- and intracellular messenger S1P fulfils multiple roles in inflammation such as mediating proinflammatory inputs or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de34d0f3fbd81809e38d981dc85c1e96
https://pubmed.ncbi.nlm.nih.gov/22732087
https://pubmed.ncbi.nlm.nih.gov/22732087
Autor:
Bona Linke, Sandra Pierre, Ovidiu Coste, Carlo Angioni, Wiebke Becker, Thorsten Jürgen Maier, Dieter Steinhilber, Claus Wittpoth, Gerd Geisslinger, Klaus Scholich
Publikováno v:
Journal of Proteome Research; Oct2009, Vol. 8 Issue 10, p4851-4859, 9p