Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Boman G. Irani"'
Autor:
Joel K. Elmquist, Xiaorui Zhang, Lana M. Gent, Carol F. Elias, Liangru Zhu, Fang Zou, Yong Xu, Nasim C. Sobhani, Sohaib A. Khan, Boman G. Irani, Thekkethil P. Nedungadi, Kathryn Davis, Lisa Hahner, Deborah J. Clegg
Publikováno v:
Cell Metabolism. 14(4):453-465
SummaryEstrogens regulate body weight and reproduction primarily through actions on estrogen receptor-α (ERα). However, ERα-expressing cells mediating these effects are not identified. We demonstrate that brain-specific deletion of ERα in female
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0bc939849cdb1bcdb5b4191ca5207f
Autor:
Hossein Yarandi, Amanda M. Shaw, Jerry Ryan Holder, James B. Chambers, Deborah J. Clegg, William J. Millard, Zhimin Xiang, Marcus C. Moore, Carrie Haskell-Luevano, Rayna M. Bauzo, Boman G. Irani, Stephen C. Benoit, Bettina Proneth
Publikováno v:
European Journal of Pharmacology. 660:80-87
The melanocortin system is well recognized to be involved in the regulation of food intake, body weight, and energy homeostasis. To probe the role of the MC 3 in the regulation of food intake, JRH322-18 a mixed MC 3 partial agonist/antagonist and MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2570a7fb3e190f5f9fda38807c638d1
https://doi.org/10.1016/j.ejphar.2010.10.101
https://doi.org/10.1016/j.ejphar.2010.10.101
Autor:
Sebastien G. Bouret, Barry E. Levin, Christa M. Patterson, Sunny Park, Ambrose A. Dunn-Meynell, Boman G. Irani
Publikováno v:
Endocrinology. 151:4270-4279
Because rearing rats in large litters (LLs) protects them from becoming obese, we postulated that LL rearing would protect rats selectively bred to develop diet-induced obesity (DIO) from becoming obese by overcoming their inborn central leptin resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10a37bbe12ff77e57d09768a96d747f
https://doi.org/10.1210/en.2010-0401
https://doi.org/10.1210/en.2010-0401
Autor:
Ambrose A. Dunn-Meynell, Boman G. Irani, Barry E. Levin, Christelle Le Foll, Christophe Magnan
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 297:R1351-R1357
Maternal obesity accentuates offspring obesity in dams bred to develop diet-induced obesity (DIO) on a 31% fat, high-sucrose, high-energy (HE) diet but has no effect on offspring of diet-resistant (DR) dams. Also, only DIO dams become obese when they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf355364ea5c9169101e1ef4e070430
https://doi.org/10.1152/ajpregu.00370.2009
https://doi.org/10.1152/ajpregu.00370.2009
Publikováno v:
Biochemical and Biophysical Research Communications. 326:638-644
The melanocortin system is involved in hypothalamic regulation of energy homeostasis. The melanocortin-4 receptor (MC4R) has been linked to both obesity and reproductive dysfunction. Deletion of the MC4R from the mouse genome has resulted in phenotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8acf52214cb6899872e414dea541fd4
https://doi.org/10.1016/j.bbrc.2004.11.084
https://doi.org/10.1016/j.bbrc.2004.11.084
Autor:
Christine G. Joseph, Carrie Haskell-Luevano, Andrzej Wilczynski, Jerry Ryan Holder, Krista R. Wilson, Boman G. Irani, Aleksandar Todorovic
Publikováno v:
Current Pharmaceutical Design. 10:3443-3479
The melanocortin pathway consists of endogenous agonists, antagonists, G-protein coupled receptors (GPCRs), and auxiliary proteins. This pathway has been identified to participate physiologically in numerous biological pathways including energy homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dce82967eda6d94c9b0e22f572f1c64
https://doi.org/10.2174/1381612043382891
https://doi.org/10.2174/1381612043382891
Autor:
Deborah J. Clegg, Boman G. Irani, Elizabeth J. Carstens, Lisa M. Hahner, Kathryn Davis, Lana M. Gent
This article is part of a Special Issue “Energy Balance”. The classical estrogen receptors, estrogen receptor-α and estrogen receptor-β are well established in the regulation of body weight and energy homeostasis in both male and female mice, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2d1735b4dddc3a382090806c8db195
https://europepmc.org/articles/PMC4051842/
https://europepmc.org/articles/PMC4051842/
Autor:
Pierre Fraikin, Bernard Pirotte, Dominique Heymann, László G. Puskás, Thomas H. Lubben, Luca Munaron, C. Philippe, Susanna Antoniotti, Haim J. Wolfson, Zsolt Lo\\'rincz, Barbara Malawska, Antal Simay, C. Garcia-Echeverria, Péter Mátyus, Alessandra Fiorio Pla, Ruth Nussinov, Marcin Gruchala, Peter J. Scammells, Martin Eggert, Szilvia Vajda, Gurbir S. Bhatia, András Varró, Bruce G. Szczepankiewicz, Panagiotis Zoumpoulakis, Ildikó Varga, Mark S. Levi, Jerry Ryan Holder, Péter Krajcsi, Margaret A. Brimble, László Ürge, Thomas Mavromoustakos, Nastiti Wijayanti, William A. Banks, William H. Bunnelle, Zhonghua Pei, Krista R. Wilson, Paola Zaccone, David W. Dunne, O.M. Zack Howard, Tomozumi Imamichi, Gregory Y.H. Lip, Christine G. Joseph, Carrie Haskell-Luevano, Maria Zervou, R. Efremov, Ákos Kocsis, G.B. Mahady, Tingjun Hou, Marcel J. de Groot, David R. Davies, Thomas D.C. Thomas, Michael R. Schrimpf, Allen B. Reitz, Stewart B. Kirton, Boman G. Irani, Seppo Ylä-Herttuala, Xiaojie Xu, Zoltán Kovári, Uwe K. Zettl, Gang Liu, Andreas Klüter, Tivadar Rettegi, Rebecca Deprez-Poulain, Péter Kovács, László Károlyházy, Dimitra Hadjipavlou-Litina, Kuo-Chen Chou, Benoit Deprez, Ferenc Darvas, Mark Levis, Donald Small, M. Iqbal Choudhary, Thang K. Chiu, Julius Gy. Papp, Michael J. Dart, Pascal de Tullio, Atta-ur-Rahman, Andrzej Wilczynski, György Dormán, Himadri Roy, Russell C. Davis, C. Bor-Luen, Stephan Immenschuh, Michael D. Sosin, Alexandra Shulman-Peleg, Anne Cooke, Davide Lovisolo, Michael J. Sutcliffe, Dina Schneidman-Duhovny, Oranit Dror, Gunther Neeck, Aleksandar Todorovic, István Pénzes, Shalini Bhardwaj, Sally A. Hutchinson, P.R. Bernstein, Pierre Francotte, Cheryl P. Kordik, David A. Jans
Publikováno v:
Frontiers in Medicinal Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f72de8108bc0fb8e384ae8a8f7537eb
https://doi.org/10.2174/97816080546401130601
https://doi.org/10.2174/97816080546401130601
Autor:
Boman G. Irani, Jerry R. Holder, Aleksandar Todorovic, Andrzej M. Wilczynski, Christine G. Joseph, Krista R. Wilson, Carrie Hask
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f71a4eb07d7509f68770e9e8716a168
https://doi.org/10.2174/978160805206610603010285
https://doi.org/10.2174/978160805206610603010285
Autor:
Andrew R. Zinn, Boman G. Irani, Ichiro Sakata, Yoichi Ueta, Carol F. Elias, Jeffrey M. Zigman, Kristen P. Tolson, David P. Olson, Mary E. Reyland, Jose Donato, Deborah J. Clegg, Bradford B. Lowell, Todd Charlton Sacktor
PKC-theta (PKC-θ), a member of the novel protein kinase C family (nPKC), regulates a wide variety of functions in the periphery. However, its presence and role in the CNS has remained largely unknown. Recently, we demonstrated the presence of PKC-θ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941d18ef9dbfe0dd7d17da2163083ef9
https://europepmc.org/articles/PMC5203986/
https://europepmc.org/articles/PMC5203986/