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Akademický článek

Screening for depression and anxiety in lung cancer patients: A real‐world study using GAD‐7 and HADS

Autor: Yi Fung Chau, Huixia Zhou, Bolu Chen, Hengqin Ren, Zixiao Ma, Xiangyang Zhang, Jianchun Duan

Publikováno v: Thoracic Cancer, Vol 15, Iss 13, Pp 1041-1049 (2024)

Abstract Background The psychological well‐being of lung cancer patients is critical in‐patient care but frequently overlooked. Methods This study, employing a cross‐sectional, questionnaire‐based design, aimed to elucidate the prevalence of

Externí odkaz: https://doaj.org/article/ba44f35f6d204d61af91de77040c3a9c

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Akademický článek

Toxic effects of TiO2 NPs in the blood-milk barrier of the maternal dams and growth of offspring

Autor: Liyang Yao, Ling Chen, Bolu Chen, Yizhou Tang, Yu Zhao, Shanji Liu, Hengyi Xu

Publikováno v: Ecotoxicology and Environmental Safety, Vol 208, Iss , Pp 111762- (2021)

Titanium dioxide nanoparticles (TiO2 NPs) are amongst the most frequently used nanomaterial in everyday consumer products, and their widespread applications have raised concerns of the consequent deleterious effects on human health, particularly to v

Externí odkaz: https://doaj.org/article/3512d5857f2241ac85fe07d400a1fc63

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Akademický článek

Nano Zinc Oxide Induced Fetal Mice Growth Restriction, Based on Oxide Stress and Endoplasmic Reticulum Stress

Autor: Bolu Chen, Wuding Hong, Pengfei Yang, Yizhou Tang, Yu Zhao, Zoraida P. Aguilar, Hengyi Xu

Publikováno v: Nanomaterials, Vol 10, Iss 2, p 259 (2020)

ZnO NPs have been assessed to show adverse effects on reproductive organs, but the molecular mechanisms of reproductive toxicity have not been sufficiently studied. In this research, the dosage effects from the oral exposure of ZnO NPs (30 nm) to pre

Externí odkaz: https://doaj.org/article/4b5bc47c97434193ad257eab9d849263

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Akademický článek

CdSe/ZnS Quantum Dots Impaired the First Two Generations of Placenta Growth in an Animal Model, Based on the Shh Signaling Pathway

Autor: Wuding Hong, Huijuan Kuang, Xingping He, Lin Yang, Pengfei Yang, Bolu Chen, Zoraida P. Aguilar, Hengyi Xu

Publikováno v: Nanomaterials, Vol 9, Iss 2, p 257 (2019)

The toxicity, especially the transgenerational toxicity of quantum dots (QDs) in vivo, is still scarcely understood in spite of great promising applications of QDs in biomedicine. In this study, the maternal status, pregnancy outcome, and fetus devel

Externí odkaz: https://doaj.org/article/7dfe7ea7df724e09aab1b44be79f13df

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Effects of QDs exposure on the reproductive and embryonic developmental toxicity in mice at various pregnancy stages

Autor: Pengfei Yang, Zoraida P. Aguilar, Ling Chen, Hengyi Xu, Bolu Chen, Fengxia Zheng, Fen Fu

Publikováno v: Toxicol Res (Camb)

Quantum dots (QDs) have recently attracted considerable attention in the biomedical fields because of their unique and excellent optical properties. However, information on their health effects, particularly in the reproductive system, is limited. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f518531e208e067fdfe288e47679993
https://doi.org/10.1093/toxres/tfaa034

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Oral exposure of titanium oxide nanoparticles induce ileum physical barrier dysfunction via Th1/Th2 imbalance

Autor: Yizhou Tang, Xinyue Xu, Liu Yang, Bolu Chen, Liyang Yao, Wuding Hong, Hengyi Xu, Zoraida P. Aguilar

Publikováno v: Environmental Toxicology. 35:982-990

In this work, we aimed to evaluate the adverse effects and the mechanism of intestinal barrier caused by titanium dioxide nanoparticles (TiO2 NPs). Here, the effects of two different dosages (300 and 1200 mg/kg) of TiO2 NPs on female mice (n = 5) wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5b3870e188040526a3dd942071d0ac
https://doi.org/10.1002/tox.22934

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ZnO Nanoparticles Induced Male Reproductive Toxicity Based on the Effects on the Endoplasmic Reticulum Stress Signaling Pathway

Autor: Liyang Yao, Bolu Chen, Yu Zhao, Zoraida P Aguilar, Wuding Hong, Ling Chen, Hengyi Xu, Yizhou Tang

Publikováno v: International Journal of Nanomedicine. 14:9563-9576

Purpose The aim of this study was to evaluate the adverse effects of ZnO NPs on male reproductive system and explore the possible mechanism. Methods In this study, the effect of oral administration of 50, 150 and 450 mg/kg zinc oxide nanoparticles (Z

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f46ef9a07416e91545c61dd5e5cd5aff
https://doi.org/10.2147/ijn.s223318

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Inhibition of testosterone synthesis induced by oral TiO(2) NPs is associated with ROS-MAPK(ERK1/2)-StAR signaling pathway in SD rat

Autor: Yizhou Tang, Shanji Liu, Xueying Tao, Zoraida P. Aguilar, Hengyi Xu, Yu Zhao, Bolu Chen

Publikováno v: Toxicol Res (Camb)

Titanium dioxide nanoparticles (TiO2 NPs) have been widely used in food, medical, and other fields; their reproductive toxicity has been reported in numerous studies. However, the relevant toxicity mechanism still requires further exploration. In thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5635a920e733691fc848a7f9bf34b181
https://europepmc.org/articles/PMC8403597/