Zobrazeno 1 - 10
of 426
pro vyhledávání: '"Bolette, Hartmann"'
Autor:
Pamela Bowman, Kashyap A Patel, Timothy J McDonald, Jens J Holst, Bolette Hartmann, Maria Leveridge, Beverley M Shields, Suzie Hammersley, Steve R Spaull, Bridget A Knight, Sarah E Flanagan, Maggie H Shepherd, Rob C Andrews, Andrew T Hattersley
Publikováno v:
Journal of Diabetes Investigation, Vol 14, Iss 12, Pp 1378-1382 (2023)
Abstract The incretin hormones glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP), are thought to be the main drivers of insulin secretion in individuals with sulfonylurea (SU)‐treated KCNJ11 permanent ne
Externí odkaz:
https://doaj.org/article/e365485b95a44b0ea326ca8035cedaad
Autor:
Jenna Elizabeth Hunt, Charlotte Bayer Christiansen, Mohammad Yassin, Bolette Hartmann, Stefan Offermanns, Lars Ove Dragsted, Jens Juul Holst, Hannelouise Kissow
Publikováno v:
Metabolites, Vol 14, Iss 7, p 395 (2024)
Short-chain fatty acids (SCFAs) are the major microbial metabolites produced from the fermentation of dietary fiber in the gut. They are recognised as secretagogues of the glucagon-like peptides, GLP-1 and GLP-2, likely mediated by the activation of
Externí odkaz:
https://doaj.org/article/bd11afd979d249969949e34732c9668d
Autor:
Sasha A.S. Kjeldsen, Lise L. Gluud, Mikkel P. Werge, Julie S. Pedersen, Flemming Bendtsen, Kleopatra Alexiadou, Tricia Tan, Signe S. Torekov, Eva W. Iepsen, Nicole J. Jensen, Michael M. Richter, Jens P. Goetze, Jørgen Rungby, Bolette Hartmann, Jens J. Holst, Birgitte Holst, Joachim Holt, Finn Gustafsson, Sten Madsbad, Maria S. Svane, Kirstine N. Bojsen-Møller, Nicolai J. Wewer Albrechtsen
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108190- (2023)
Summary: Inhibitors of neprilysin improve glycemia in patients with heart failure and type 2 diabetes (T2D). The effect of weight loss by diet, surgery, or pharmacotherapy on neprilysin activity (NEPa) is unknown. We investigated circulating NEPa and
Externí odkaz:
https://doaj.org/article/541de04b6ddd4e19900f1ffa4e360c15
Autor:
Lasse Hartmann Schmidt, Jesper Stensig Aa, Bolette Hartmann, Gunvor Iben Madsen, Niels Qvist, Mark Bremholm Ellebæk
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background To investigate the effects of a reversed segment of the distal small intestine to improve weight gain in an experimental short bowel syndrome (SBS) model in piglets. Methods Twenty-four piglets underwent resection of 70% of the di
Externí odkaz:
https://doaj.org/article/0ef9ab2c5def4ddb9b3e3712a3f0651d
Autor:
Sarina Gadgaard, Johanne A. Windeløv, Sine P. Schiellerup, Jens J. Holst, Bolette Hartmann, Mette M. Rosenkilde
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114383- (2023)
Background and Purpose: Glucagon-like peptide-2 (GLP-2) is secreted postprandially from enteroendocrine Lcells and has anabolic action on gut and bone. Short-acting teduglutide is the only approved GLP-2 analog for the treatment of short-bowel syndro
Externí odkaz:
https://doaj.org/article/46cce5d1d32b4af9970e1b38801907d6
Autor:
Katrine Brodersen, Maike Mose, Ulla Ramer Mikkelsen, Jens Otto Lunde Jørgensen, Michael Festersen Nielsen, Niels Møller, Anne‐Marie Wegeberg, Christina Brock, Bolette Hartmann, Jens Juul Holst, Nikolaj Rittig
Publikováno v:
Physiological Reports, Vol 10, Iss 18, Pp n/a-n/a (2022)
Abstract Severe systemic inflammation is associated with nausea, loss of appetite, and delayed gastric emptying, which increases hospitalization admission length and mortality rate. There is a lack of human controlled studies exploring gastric emptyi
Externí odkaz:
https://doaj.org/article/de35ba70c46f41b9a3d8b2b2bd5c84fc
Autor:
Mads N. Thomsen, Mads J. Skytte, Amirsalar Samkani, Arne Astrup, Mogens Fenger, Jan Frystyk, Bolette Hartmann, Jens J. Holst, Thomas M. Larsen, Sten Madsbad, Faidon Magkos, Jens F. Rehfeld, Steen B. Haugaard, Thure Krarup
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
BackgroundCarbohydrate restriction may benefit β-cell function and glucose metabolism in type 2 diabetes (T2D) but also leads to weight loss which in itself is beneficial.MethodsIn order to determine the additional effect of carbohydrate restriction
Externí odkaz:
https://doaj.org/article/8135e6a309234cc6a8411eafd7c863f4
Autor:
Justyna Modrzynska, Christine F Klein, Kasper Iversen, Henning Bundgaard, Bolette Hartmann, Maike Mose, Nikolaj Rittig, Niels Møller, Jens J Holst, Nicolai J Wewer Albrechtsen
Publikováno v:
Endocrine Connections, Vol 10, Iss 2, Pp 205-213 (2021)
Objective: Glucagon and glucagon-like peptide-1 (GLP-1) originate from the common precursor, proglucagon, and their plasma concentrations have been reported to be increased during inflammatory conditions. Increased blood glucose levels are frequently
Externí odkaz:
https://doaj.org/article/f1211a524b0c42eea2e21cde29bc7ea0
Autor:
Nora Hedbäck, Morten Hindsø, Kirstine N. Bojsen-Møller, Adelaide K. Linddal, Nils B. Jørgensen, Carsten Dirksen, Andreas Møller, Viggo B. Kristiansen, Bolette Hartmann, Jens J. Holst, Maria S. Svane, Sten Madsbad
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Background and aimsThe metabolic consequences after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are often studied using a liquid mixed meal. However, liquid meals may not be representative of the patients’ everyday diet. We therefor
Externí odkaz:
https://doaj.org/article/6389ff278bd24b9cb9167f06cfa53825
Autor:
Lewin Small, Amy Ehrlich, Jo Iversen, Stephen P. Ashcroft, Kajetan Trošt, Thomas Moritz, Bolette Hartmann, Jens J. Holst, Jonas T. Treebak, Juleen R. Zierath, Romain Barrès
Publikováno v:
Molecular Metabolism, Vol 57, Iss , Pp 101440- (2022)
Objective: The glucose tolerance test (GTT) is widely used in preclinical research to investigate glucose metabolism, but there is no standardised way to administer glucose. The aim of this study was to directly compare the effect of the route of glu
Externí odkaz:
https://doaj.org/article/77e12f244ee14592b5d0b6bff12b2c30