Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Boleslaw Marczynski"'
Autor:
Swaantje Casjens, Rainer Van Gelder, Holger M. Koch, Andrea Hartwig, Thomas Brüning, Heiko U. Käfferlein, Martin Lehnert, Boleslaw Marczynski, Anne Lotz, Tobias Weiss, Evelyn Heinze, Thomas Behrens, Jens Uwe Hahn, Beate Pesch, Peter Welge, Monika Raulf
Publikováno v:
Archives of Toxicology
The International Agency for Research on Cancer considers the carcinogenicity of welding fume of priority for re-evaluation. Genotoxic effects in experimental animals are still inconclusive. Here, we investigated the association of personal exposure
Autor:
Boleslaw Marczynski, Heiko U. Käfferlein, Jürgen Angerer, Beate Pesch, Thomas Brüning, Hans-Peter Rihs, Kurt Straif, P. Simon, Michael Wilhelm
Publikováno v:
Archives of Toxicology. 86:1317-1321
We previously reported DNA strand break frequencies and adduct levels of 8-oxo-7,8-dihydro-20-deoxyguanosine (8-oxo-dGuo) in 171 blood samples of coke oven, refractory, graphite electrode, and converter workers exposed to polycyclic aromatic hydrocar
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 75:588-596
The influence of DNA repair gene polymorphisms (XRCC1: Arg194Trp, Arg280His, Arg399Gln; APE1: Asp148Glu; hOGG1: Ser326Cys) on oxidative DNA damage is controversial and was investigated in 214 German workers with occupational exposure to vapors and ae
Autor:
Monika Raulf-Heimsoth, Anne Lotz, Benjamin Kendzia, Beate Pesch, Peter Welge, Hans-Peter Rihs, Thomas Brüning, Boleslaw Marczynski
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 75:533-543
Circadian variations in immune defense and tissue repair may interfere with shift effects of occupational exposure when investigating biomarkers in cross-shift studies. This investigation compared biomarkers of inflammation and DNA damage in 59 nonsm
Autor:
Benjamin Kendzia, Beate Engelhardt, Monika Raulf-Heimsoth, Heiko U. Käfferlein, Boleslaw Marczynski, Dietmar Breuer, Birgit K. Schindler, Jürgen Angerer, Beate Pesch, T. Mensing, Evelyn Heinze, Rainer Bramer, Anne Spickenheuer, Eun-Hyun Lee, Thomas Brüning, Peter Welge
Publikováno v:
Archives of Toxicology. 85:53-64
To study the associations between exposure to vapours and aerosols of bitumen and genotoxic effects, a cross-sectional and cross-shift study was conducted in 320 exposed workers and 118 non-exposed construction workers. Ambient air measurements were
Autor:
Reinhold Rühl, Jürgen Angerer, Bernd Schilling, Rainer Bramer, Dieter Höber, Boleslaw Marczynski, Uwe Musanke, Thomas Brüning, Dietmar Breuer, Peter Welge, Albrecht Seidel, Benjamin Kendzia, Christoph Emmel, Monika Raulf-Heimsoth, Evelyn Heinze, Anne Spickenheuer, Jens-Uwe Hahn, Beate Pesch
Publikováno v:
Archives of Toxicology. 85:11-20
The chemical complexity of emissions from bitumen applications is a challenge in the assessment of exposure. Personal sampling of vapours and aerosols of bitumen was organized in 320 bitumen-exposed workers and 69 non-exposed construction workers dur
Autor:
Beate Pesch, Monika Raulf-Heimsoth, Reinhold Rühl, Peter Rode, Rainer Bramer, Evelyn Heinze, Boleslaw Marczynski, Anne Spickenheuer, Uwe Musanke, Thomas Brüning, Dietmar Breuer, Stefan Gabriel, Dieter Höber, Udo Knecht, Jens-Uwe Hahn, Benjamin Kendzia, Peter Welge
Publikováno v:
Archives of Toxicology. 85:21-28
Bitumen (referred to as asphalt in the United States) is a widely used construction material, and emissions from hot bitumen applications have been a long-standing health concern. One objective of the Human Bitumen Study was to identify potential det
Autor:
Monika Raulf-Heimsoth, Thomas Brüning, Boleslaw Marczynski, Heiko U. Käfferlein, Vosshans B, Benjamin Kendzia, Rainer Bramer, Eun-Hyun Lee, Gerda Borowitzki, Beate Pesch
Publikováno v:
Human & Experimental Toxicology. 29:721-729
DNA strand breaks were determined in leucocytes of induced sputum (IS) and compared with DNA strand breaks in blood lymphocytes from 42 bitumen-exposed workers pre and post shift. Comet assay results were expressed in arbitrary units based on visual
Autor:
Roberta Andreoli, Monika Hanova, Ludmila Vodickova, Alessio Naccarati, Boleslaw Marczynski, Pavel Hlavac, Antonio Mutti, Pavel Vodicka, Paola Manini, Paola Mozzoni, Giuseppe De Palma
Publikováno v:
Toxicology Letters. 190:41-47
This study investigated nucleic acid oxidation associated with styrene exposure, mRNA expression levels of hOGG1 gene and the role of the genetic polymorphism Ser326Cys of human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) in 60 styrene-exposed workers a
Autor:
Heiko U. Käfferlein, Michael Scherenberg, Thomas Brüning, Hans-Peter Rihs, Boleslaw Marczynski, Beate Engelhardt, Albrecht Seidel, Monika Raulf-Heimsoth, Bernd Rossbach, Jens-Uwe Hahn, Kurt Straif, Anja Erkes, Jürgen Angerer, Sylvia Rabstein, Michael Wilhelm, Ralf Preuss, Beate Pesch, Ansgar Adams
Publikováno v:
Marczynski, Boleslaw; Pesch, Beate; Wilhelm, Michael; Rossbach, Bernd; Preuss, Ralf; Hahn, Jens-Uwe; Rabstein, Sylvia; Raulf-Heimsoth, Monika; Seidel, Albrecht; Rihs, Hans-Peter; Adams, Ansgar; Scherenberg, Michael; Erkes, Anja; Engelhardt, Beate; Straif, Kurt; Käfferlein, Heiko Udo; Angerer, Jürgen; Brüning, Thomas (2009). Occupational exposure to polycyclic aromatic hydrocarbons and DNA damage by industry: a nationwide study in Germany. Archives of toxicology, 83(10), pp. 947-57. Berlin: Springer 10.1007/s00204-009-0444-9
Exposure to polycyclic aromatic hydrocarbons (PAH) and DNA damage were analyzed in coke oven (n = 37), refractory (n = 96), graphite electrode (n = 26), and converter workers (n = 12), whereas construction workers (n = 48) served as referents. PAH ex