Zobrazeno 1 - 10
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pro vyhledávání: '"Boldini, A."'
Accurate prediction of drug-target interactions is critical for advancing drug discovery. By reducing time and cost, machine learning and deep learning can accelerate this laborious discovery process. In a novel approach, BarlowDTI, we utilise the po
Externí odkaz:
http://arxiv.org/abs/2408.00040
We address the problem of controlling the density of a large ensemble of follower agents by acting on group of leader agents that interact with them. We formulate the problem as a system of coupled partial integro-differential equations describing fo
Externí odkaz:
http://arxiv.org/abs/2406.01804
Autor:
Boldini, Pietro Carlo, Bugeat, Benjamin, Peeters, Jurriaan W. R., Kloker, Markus, Pecnik, Rene
In the region close to the thermodynamic critical point and in the proximity of the pseudo-boiling (Widom) line, strong property variations substantially alter the growth of modal instabilities, as revealed in Ren et al. (J. Fluid Mech., vol. 871, 20
Externí odkaz:
http://arxiv.org/abs/2403.06181
Publikováno v:
J. Chem. Inf. Model. 2024, 64, 12, 4640-4650
The success of drug discovery and development relies on the precise prediction of molecular activities and properties. While in silico molecular property prediction has shown remarkable potential, its use has been limited so far to assays for which l
Externí odkaz:
http://arxiv.org/abs/2401.04478
Publikováno v:
Royal Society Open Science, Vol 11, Iss 9 (2024)
Stigmergy, the indirect communication between agents of a swarm through dynamic environmental modifications, is a fundamental self-organization mechanism of animal swarms. Engineers have drawn inspiration from stigmergy to establish strategies for th
Externí odkaz:
https://doaj.org/article/4278a3be67104b6898d3ecd5752bd1ef
This paper addresses the stability of plane Couette flow in the presence of strong density and viscosity stratifications. It demonstrates the existence of a generalised inflection point that satisfies the generalised Fjortoft's criterion of instabili
Externí odkaz:
http://arxiv.org/abs/2211.04935
In this paper, we propose a method to control large-scale multiagent systems swarming in a ring. Specifically, we use a continuification-based approach that transforms the microscopic, agent-level description of the system dynamics into a macroscopic
Externí odkaz:
http://arxiv.org/abs/2209.15060
Autor:
Francesco Ditonno, Riccardo Bertolo, Alessandro Veccia, Sonia Costantino, Francesca Montanaro, Francesco Artoni, Alberto Baielli, Michele Boldini, Davide Brusa, Vincenzo De Marco, Filippo Migliorini, Antonio Benito Porcaro, Riccardo Rizzetto, Maria Angela Cerruto, Riccardo Autorino, Alessandro Antonelli
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The study aimed to evaluate the impact of abdominal drain placement (vs. omission) on perioperative outcomes of robot-assisted partial nephrectomy (RAPN), focusing on complications, time to canalization, deambulation, and pain management. A
Externí odkaz:
https://doaj.org/article/e42d8901697d4eba9630d8f5fc7bebb3
Publikováno v:
ACS Central Science, Vol 10, Iss 4, Pp 823-832 (2024)
Externí odkaz:
https://doaj.org/article/365a5f1623884cc5b1e73d15d5c14d9c
Autor:
Davide Boldini, Davide Ballabio, Viviana Consonni, Roberto Todeschini, Francesca Grisoni, Stephan A. Sieber
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Natural products are a diverse class of compounds with promising biological properties, such as high potency and excellent selectivity. However, they have different structural motifs than typical drug-like compounds, e.g., a wider range of m
Externí odkaz:
https://doaj.org/article/46f966aabfba49c5aca910c8dd8a61cc