Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bolanle M. Famakin"'
Autor:
Bolanle M. Famakin, Orest Tsymbalyuk, Natalia Tsymbalyuk, Svetlana Ivanova, Seung Kyoon Woo, Min Seong Kwon, Volodymyr Gerzanich, J. Marc Simard
Publikováno v:
Neurology Research International, Vol 2020 (2020)
Limited, and underutilized, therapeutic options for acute stroke require new approaches to treatment. One such potential approach involves better understanding of innate immune response to brain injury such as acute focal cerebral ischemia. This incl
Externí odkaz:
https://doaj.org/article/5c28bfe1c460459795d7e9974e458716
Autor:
Laura B, Eisenmenger, Anthony, Peret, Bolanle M, Famakin, Alma, Spahic, Grant S, Roberts, Jeremy H, Bockholt, Kevin M, Johnson, Jane S, Paulsen
Publikováno v:
Translational Research. 254:41-53
Alzheimer's disease (AD) is the most common cause of dementia and is characterized by progressive neurodegeneration and cognitive decline. Understanding the pathophysiology underlying AD is paramount for the management of individuals at risk of and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d0732048c2b4e8499117dc009c092c
https://doi.org/10.1016/j.trsl.2022.12.003
https://doi.org/10.1016/j.trsl.2022.12.003
Autor:
Bolanle M Famakin, Raghu Vemuganti
Publikováno v:
Molecular Neurobiology. 57:2690-2701
A robust innate immune activation leads to downstream expression of inflammatory mediators that amplify tissue damage and consequently increase the morbidity after stroke. The Toll-like receptor 4 (TLR4) pathway is a major innate immune pathway activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70df6143b53b6d40f3588d01b9302b3e
https://doi.org/10.1007/s12035-020-01906-5
https://doi.org/10.1007/s12035-020-01906-5
Autor:
J. Marc Simard, Bolanle M. Famakin, Svetlana Ivanova, Cigdem Tosun, Natalia Tsymbalyuk, Rudy J. Castellani, Volodymyr Gerzanich, Min Seong Kwon, Rupal I. Mehta
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 74:835-849
The nonselective monovalent cation channel transient receptor potential melastatin 4 (Trpm4) is transcriptionally upregulated in neural and vascular cells in animal models of brain infarction. It associates with sulfonylurea receptor 1 (Sur1) to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453317ab2c3202beb1830be9b0d7fbab
https://doi.org/10.1097/nen.0000000000000223
https://doi.org/10.1097/nen.0000000000000223
Autor:
Vicki S. Hertzberg, Kerrie Krompf, Bolanle M. Famakin, William M. McClellan, Paul S. Weiss, Rodney Presley, Michael Frankel, Herbert R. Karp
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 19:17-22
Background Mortality remains unacceptably high among patients hospitalized for acute stroke. Additional knowledge about factors that contribute to mortality after stroke is important for instituting therapies to lower mortality. We sought to determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf3a17a36c03461835c0dae89fc1059
https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.01.015
https://doi.org/10.1016/j.jstrokecerebrovasdis.2009.01.015
Autor:
Bolanle M Famakin
Publikováno v:
Aging and Disease.
It is currently well established that the immune system is activated in response to transient or focal cerebral ischemia. This acute immune activation occurs in response to damage, and injury, to components of the neurovascular unit and is mediated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bb0212355f78c95ac64c9a5a0ecb3c
https://doi.org/10.14336/ad.2014.0500307
https://doi.org/10.14336/ad.2014.0500307
To better understand the role of downstream Toll-like receptor (TLR) signaling during acute cerebral ischemia, we performed cDNA microarrays, on brain RNA, and cytokine arrays, on serum, from wild type (WT), MyD88−/− and TRIF-mutant mice, at base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4c905374779914263789db8bdc6990
https://europepmc.org/articles/PMC3915199/
https://europepmc.org/articles/PMC3915199/
Publikováno v:
Journal of Neuroinflammation, Vol 9, Iss 1, p 174 (2012)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Deletion of some Toll-like receptors (TLRs) affords protection against cerebral ischemia, but disruption of their known major downstream adaptors does not. To determine whether compensation in the production of downstream effectors by one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0a2148b185a76da63bf4ae320604be
http://www.jneuroinflammation.com/content/9/1/174
http://www.jneuroinflammation.com/content/9/1/174
Publikováno v:
Stroke. 43
Background: The Toll-like receptor (TLR) signaling pathway plays an important role in the innate immune response to a number of inflammatory conditions and in the innate immune response to ischemia. However, the downstream TLR signaling events that o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f32958dd0d9f24053aeaf649d1b414
https://doi.org/10.1161/str.43.suppl_1.a3742
https://doi.org/10.1161/str.43.suppl_1.a3742
Autor:
John M. Hallenbeck, J. Bembry, Bolanle M Famakin, Christl A. Ruetzler, Yongshan Mou, Dragan Maric
Toll-like receptor (TLR) signaling plays an important role in cerebral ischemia, but downstream signaling events, which can be organ-specific, are incompletely understood. We thereby investigated involvement of the MyD88-dependent (MyD88) and MyD88-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db5539bf90a5b580c8a166632a55bc9
https://europepmc.org/articles/PMC3126100/
https://europepmc.org/articles/PMC3126100/