A covalent creatine kinase inhibitor ablates glioblastoma migration and sensitizes tumors to oxidative stress.

Autor: Katz JL; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Geng Y; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Billingham LK; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Sadagopan NS; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., DeLay SL; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Subbiah J; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Chia TY; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA.; Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., McManus G; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Wei C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Wang H; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Lin H; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Silvers C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Boland LK; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA.; Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital, Chicago, IL, USA., Wang S; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Wan H; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA.; Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Hou D; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Vázquez-Cervantes GI; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Arjmandi T; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Shaikh ZH; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA., Zhang P; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA.; Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Ahmed AU; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA.; Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Tiek DM; Department of Neurology, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Ave, Chicago, IL, 60611, USA., Lee-Chang C; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA.; Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Chouchani ET; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Miska J; Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, 676 N St. Clair, Suite 2210, Chicago, IL, 60611, USA. jason.miska@northwestern.edu.; Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. jason.miska@northwestern.edu.

Publikováno v: Scientific reports [Sci Rep] 2024 Sep 20; Vol. 14 (1), pp. 21959. Date of Electronic Publication: 2024 Sep 20.

Corrigendum to "Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivo" [Molecular Metabolism 36 (2020) 100965].

Autor: Markan KR; Department of Neuroscience and Pharmacology, Iowa City, IA, 52242, USA; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA. Electronic address: krmarkan@gmail.com., Boland LK; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA; Roy J. Carver Department of Biomedical Engineering, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., King-McAlpin AQ; Department of Neuroscience and Pharmacology, Iowa City, IA, 52242, USA; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA., Claflin KE; Department of Neuroscience and Pharmacology, Iowa City, IA, 52242, USA; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA; Iowa Neurosciences Institute, Iowa City, IA, 52242, USA., Leaman MP; Department of Neuroscience and Pharmacology, Iowa City, IA, 52242, USA; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA., Kemerling MK; Department of Neuroscience and Pharmacology, Iowa City, IA, 52242, USA; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA., Stonewall MM; Department of Neuroscience and Pharmacology, Iowa City, IA, 52242, USA; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA., Amendt BA; Department of Anatomy and Cell Biology and the Craniofacial Anomalies Research Center, Iowa City, IA, 52242, USA., Ankrum JA; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA; Roy J. Carver Department of Biomedical Engineering, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA., Potthoff MJ; Department of Neuroscience and Pharmacology, Iowa City, IA, 52242, USA; Fraternal Order of Eagles Diabetes Research Center, Iowa City, IA, 52242, USA; Iowa Neurosciences Institute, Iowa City, IA, 52242, USA; Department of Veterans Affairs Medical Center, Iowa City, IA, 52242, USA.

Publikováno v: Molecular metabolism [Mol Metab] 2021 Feb; Vol. 44, pp. 101148. Date of Electronic Publication: 2020 Dec 25.

Dose and duration of interferon γ pre-licensing interact with donor characteristics to influence the expression and function of indoleamine-2,3-dioxygenase in mesenchymal stromal cells.

Autor: Boyt DT; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA., Boland LK; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA., Burand AJ Jr; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA., Brown AJ; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, USA.; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Denver, CO, USA.; Department of Biomedical Research, National Jewish Health, Denver, CO, USA., Ankrum JA; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, USA.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA.

Publikováno v: Journal of the Royal Society, Interface [J R Soc Interface] 2020 Jun; Vol. 17 (167), pp. 20190815. Date of Electronic Publication: 2020 Jun 17.

Aggregation of Human Mesenchymal Stromal Cells Eliminates Their Ability to Suppress Human T Cells.

Autor: Burand AJ Jr; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, United States.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, United States., Di L; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, United States.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, United States., Boland LK; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, United States.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, United States., Boyt DT; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, United States.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, United States., Schrodt MV; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, United States.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, United States., Santillan DA; Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Center for Immunology and Immune Based Diseases, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Center for Hypertension Research, University of Iowa, Iowa City, IA, United States., Ankrum JA; Roy J. Carver Department of Biomedical Engineering, College of Engineering, University of Iowa, Iowa City, IA, United States.; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2020 Feb 25; Vol. 11, pp. 143. Date of Electronic Publication: 2020 Feb 25 (Print Publication: 2020).

Depletion of macrophages in CD11b diphtheria toxin receptor mice induces brain inflammation and enhances inflammatory signaling during traumatic brain injury.

Autor: Frieler RA; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Nadimpalli S; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA., Boland LK; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA., Xie A; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA., Kooistra LJ; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA., Song J; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA., Chung Y; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA., Cho KW; Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Lumeng CN; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA; Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI 48109, USA., Wang MM; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Neurology, Veterans Administration Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA., Mortensen RM; Department of Molecular and Integrative Physiology, University of Michigan Medical School, 1137 E. Catherine St., 7708 Medical Science II, Ann Arbor, MI 48109, USA; Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address: rmort@umich.edu.

Publikováno v: Brain research [Brain Res] 2015 Oct 22; Vol. 1624, pp. 103-112. Date of Electronic Publication: 2015 Jul 21.