Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Bok-Seok Kim"'
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Fas-associated factor 1 (FAF1) has been implicated in Parkinson’s disease (PD) and activates the cell death machinery in the cytosol. However, the presence of extracellular FAF1 has not been studied. Methods Serum-free condition
Externí odkaz:
https://doaj.org/article/47410e10d97140068545d938ed07c0d4
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-17 (2018)
Abstract Background Aberrant cell death induced by ischemic stress is implicated in the pathogenesis of ischemic diseases. Fas-associated factor 1 (FAF1) has been identified as a death-promoting protein. This study demonstrates that FAF1 functions in
Externí odkaz:
https://doaj.org/article/9675dfd449764957888e3c1b7f9f471a
Autor:
Bok-Seok Kim, Jin-A Song, Ki-Hong Jang, Taeik Jang, Bumjun Jung, Sung-Eun Yoo, Jae Moon Lee, Eunhee Kim
Publikováno v:
ACS Chemical Neuroscience. 13:806-817
α-Synuclein accumulation is implicated in the pathogenesis of neurodegenerative diseases, including Parkinson's disease (PD). Previously, we reported that Fas-associated factor 1 (FAF1), which plays a role in PD pathogenesis, potentiates α-synuclei
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-17 (2020)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Background Fas-associated factor 1 (FAF1) has been implicated in Parkinson’s disease (PD) and activates the cell death machinery in the cytosol. However, the presence of extracellular FAF1 has not been studied. Methods Serum-free conditioned medium
Publikováno v:
Journal of Agriculture & Life Science. 53:153-162
The Eurytoma maslovskii conduces the unexpected plum dropping. It stayed overwinter inside the pits of the dropped plums and able to oviposit on plum surface when the diameter of the plums are over 16 mm prior to endocarp hardening. To control this h
Publikováno v:
The FASEB Journal. 35
Impairment of protein clearance mechanisms leads to α-synuclein accumulation in dopaminergic neurons, contributing to the pathogenesis of Parkinson's disease (PD). Based on the finding that Fas-associated factor 1 (FAF1), a positive modulator of PD,
Additional file 8 Figure S7. Recipient cell death was not changed in response to CMs of SH-SY5Y cells transtected with FAF1 with different tags. Donor cells were transfected with VC, no-tagged FAF1, and HA-FAF1 plasmid. At 24 h after transfection, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c86f728f043c3600f7aecb2805c6ac
Additional file 9 Figure S8. CM from FAF1-transtected cells induces neighboring cell death via caspase-3 activation. Donor cells were transfected with VC or 3xFlag-FAF1 plasmid. At 24 h after transfection, the culture medium was replaced with serum-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d1f0bdbe80f4682b521f0fb2fd3cbf
Additional file 2 Figure S1. FAF1 secretion is not an artificial effect. a Cells were transfected with VC or 3xFlag-FAF1 plasmid. At 24 h after transfection, cell death was determined by measuring propidium iodide uptake using a flow cytometer (n = 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c6c84e4afffb0857e45981a6bf7d7f
Additional file 7 Figure S6. FAF1 upregulation increases exosome number. SH-SY5Y cells plated on 150 mm dishes were transfected with VC or 3xFlag-FAF1 plasmid. At 24 h after transfection, the culture medium was replaced with exosome-depleted medium,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308a4785bed97b8ee353dbdecd2a33ff