Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Bojana, Jakic"'
Autor:
William J. Olson, Bojana Jakic, Verena Labi, Johannes Woelk, Emmanuel Derudder, Gottfried Baier, Natascha Hermann-Kleiter
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
B cells are key mediators of humoral immunity. Mature B cells fall into various sub-classes that can be separated by their ontogeny, expression of cell surface markers, anatomical location, and function. B1 subsets play important roles in natural imm
Externí odkaz:
https://doaj.org/article/e2139a73e90d43b3a56eebf28e146f74
Autor:
Bojana Jakic, William J. Olson, Kerstin Siegmund, Victoria Klepsch, Janine Kimpel, Verena Labi, Dietmar Zehn, Gottfried Baier, Natascha Hermann-Kleiter
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-16 (2021)
Abstract Memory formation is a hallmark of T cell-mediated immunity, but how differentiation into either short-lived effector cells (SLECs, CD127−KLRG1+) or memory precursors cells (MPECs, CD127+KLRG1−) and subsequent regulation of long-term memo
Externí odkaz:
https://doaj.org/article/16f2165276a045e28562fa2d8f16d12a
Publikováno v:
Bio-Protocol, Vol 11, Iss 23 (2021)
Pathogens such as bacteria, viruses, fungi, or protozoa can cause acute and chronic infections in their hosts. The intracellular bacterium Listeria monocytogenes serves as a model pathogen to assess the molecular mechanisms regulating CD8 T cell acti
Externí odkaz:
https://doaj.org/article/5ae1fc9d439c46d697278efc357e74a1
Autor:
Victoria Klepsch, Natascha Hermann-Kleiter, Patricia Do-Dinh, Bojana Jakic, Anne Offermann, Mirjana Efremova, Sieghart Sopper, Dietmar Rieder, Anne Krogsdam, Gabriele Gamerith, Sven Perner, Alexandar Tzankov, Zlatko Trajanoski, Dominik Wolf, Gottfried Baier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Immune checkpoints blockade (ICB) is a viable anti-cancer strategy. Here the authors show that nuclear receptor NR2F6 acts as an immune checkpoint in T cells and, using mouse models and human T cells, they show NR2F6 inhibition might improve current
Externí odkaz:
https://doaj.org/article/6708fd1e3e99478a95dc46aa8093f81c
Autor:
William J. Olson, Bojana Jakic, Verena Labi, Katia Schoeler, Michaela Kind, Victoria Klepsch, Gottfried Baier, Natascha Hermann-Kleiter
Publikováno v:
Cell Reports, Vol 28, Iss 11, Pp 2878-2891.e5 (2019)
Summary: CD4 T follicular helper (Tfh) cells are specialized in helping B cells during the germinal center (GC) reaction and ultimately promote long-term humoral immunity. Here we report that loss of the nuclear orphan receptor NR2F6 causes enhanced
Externí odkaz:
https://doaj.org/article/c6e258769d22419c911e8d6adc256291
Autor:
Andreas Meryk, Luca Pangrazzi, Magdalena Hagen, Florian Hatzmann, Brigitte Jenewein, Bojana Jakic, Natascha Hermann-Kleiter, Gottfried Baier, Juulia Jylhävä, Mikko Hurme, Klemens Trieb, Beatrix Grubeck-Loebenstein
Publikováno v:
Cell Reports, Vol 26, Iss 10, Pp 2681-2691.e5 (2019)
Summary: Fc receptor for IgM (FcμR)-deficient mice display dysregulated function of neutrophils, dendritic cells, and B cells. The relevance of FcμR to human T cells is still unknown. We show that FcμR is mostly stored inside the cell and that sur
Externí odkaz:
https://doaj.org/article/dcbb1609c763493884d532e733c0a63b
Autor:
Milena Petkova, Marle Kraft, Simon Stritt, Ines Martinez-Corral, Henrik Ortsäter, Michael Vanlandewijck, Bojana Jakic, Eulàlia Baselga, Sandra D. Castillo, Mariona Graupera, Christer Betsholtz, Taija Mäkinen
Publikováno v:
Journal of Experimental Medicine. 220
Oncogenic mutations in PIK3CA, encoding p110α-PI3K, are a common cause of venous and lymphatic malformations. Vessel type–specific disease pathogenesis is poorly understood, hampering development of efficient therapies. Here, we reveal a new immun
Autor:
Maja Buszko, Benno Cardini, Rupert Oberhuber, Lukas Oberhuber, Bojana Jakic, Anja Beierfuss, Georg Wick, Giuseppe Cappellano
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173088 (2017)
Thymoglobulin (ATG) is a polyclonal rabbit antibody against human thymocytes used as a T cell-depleting agent to prevent or treat allotransplant rejection. The aim of the present study was to investigate the effect of low dose ATG treatment exclusive
Externí odkaz:
https://doaj.org/article/3fe561f2207441f98f649c400893d02d
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179383 (2017)
Atherosclerosis is the leading cause of death in the world. We have previously shown that expression of heat shock protein 60 (HSP60) on the surface of endothelial cells is the main cause of initiating the disease as it acts as a T cell auto-antigen
Externí odkaz:
https://doaj.org/article/78187456360d4a89b36752d6b8909a5c
Autor:
Milena Petkova, Marle Kraft, Simon Stritt, Ines Martinez-Corral, Henrik Ortsäter, Ying Sun, Michael Vanlandewijck, Bojana Jakic, Eulàlia Baselga, Sandra D. Castillo, Mariona Graupera, Christer Betsholtz, Taija Mäkinen
Vascular malformations are congenital, chronically debilitating diseases. Somatic oncogenic mutations in PIK3CA, encoding p110α-PI3K, specifically cause venous and lymphatic malformations (LM), yet the basis of vessel type-restricted disease manifes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31552a79f6da28021b84ec3456306a4d
https://doi.org/10.1101/2022.05.22.492950
https://doi.org/10.1101/2022.05.22.492950