Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bojan Vilagos"'
Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.
Autor:
Kseniya Khamina, Alexander Lercher, Michael Caldera, Christopher Schliehe, Bojan Vilagos, Mehmet Sahin, Lindsay Kosack, Anannya Bhattacharya, Peter Májek, Alexey Stukalov, Roberto Sacco, Leo C James, Daniel D Pinschewer, Keiryn L Bennett, Jörg Menche, Andreas Bergthaler
Publikováno v:
PLoS Pathogens, Vol 13, Iss 12, p e1006758 (2017)
RNA-dependent RNA polymerases (RdRps) play a key role in the life cycle of RNA viruses and impact their immunobiology. The arenavirus lymphocytic choriomeningitis virus (LCMV) strain Clone 13 provides a benchmark model for studying chronic infection.
Externí odkaz:
https://doaj.org/article/61f6526a55ef46658467aab0a567e0fd
Autor:
Noemi Meszaros, Karin Lind, Robert Sehlke, Bojan Vilagos, Nikolaus Krall, Gregory I. Vladimer, Heinz Sill
Publikováno v:
British Journal of Haematology. 200
Autor:
Irene Gutierrez-Perez, Joost Van Ham, Valentin Aranha, Rin Okumura, Elisabeth Waltenberger, Isabella Alt, Claudia Baumgaertler, Maja Stulic, Edgar Petru, Christoph Minichsdorfer, Lukas Hefler, Judith Lafleur, Nikolaus Krall, Thorsten Füreder, Gregory Ian Vladimer, Robert Sehlke, Bojan Vilagos
Publikováno v:
Cancer Research. 82:1893-1893
Background: High unmet need of ovarian cancer (OC) suggests the discovery of new targeted therapeutics is crucial to improve patient prognosis. Unlike artificial model systems such as cell lines, primary cancer samples recapitulate the complexity of
Autor:
Luigi Tortola, Rubina Koglgruber, Gerald Wirnsberger, Christoph Klein, Miriam Wöhner, Melanie Kogler, Meinrad Busslinger, Josef M. Penninger, Astrid Hagelkruys, Johannes Stadlmann, Maria Novatchkova, David Hoffmann, Andreas Bergthaler, Georg Schett, Bojan Vilagos, Marion Horrer, Peter Bönelt, Gustav Jonsson, Ulrike Steffen
Publikováno v:
The Journal of Experimental Medicine
Jagn1 deficiency results in alterations in the endoplasmic reticulum (ER) and Golgi apparatus of antibody-producing cells, reduced antibody secretion, and aberrant IgG N-glycosylation. The data uncover a key role for JAGN1 and ER stress in antibody g
Autor:
Florian Rohrer, Nikolaus Krall, Lukas Hefler, Bojan Vilagos, Robert Sehlke, Gregory I. Vladimer, Laudia Hadjari, Diogo Tomaz, Judith Lafleur, Valentin Aranha, Irene Gutierrez Perez, Joost van Ham
Publikováno v:
Cancer Research. 81:1303-1303
Introduction: The paradigm of precision oncology is the selection of optimal therapy for individual patients. However, disease complexity prevents most cases from having a clear correlation between genetics and response, and programs using driver mut
Autor:
Reshma Taneja, Moritz J. Rossner, Meinrad Busslinger, Taras Kreslavsky, Daniela Kostanova Poliakova, Markus Jaritz, Hiromi Tagoh, Bojan Vilagos, Siegfried Weiss, Tanja A. Schwickert, Miriam Wöhner
Publikováno v:
Nature Immunology. 18:442-455
Innate-like B-1a cells provide a first line of defense against pathogens, yet little is known about their transcriptional control. Here we identified an essential role for the transcription factor Bhlhe41, with a lesser contribution by Bhlhe40, in co
Autor:
Keiryn L. Bennett, Gregory M. Woods, Alexandra Popa, David A. Rosa, Ji Sung Park, Hannah V. Siddle, Christoph Bock, Patrick T. Gunning, Gary Tin, Andreas Bergthaler, Anna Orlova, Lindsay Kosack, Bettina Wingelhofer, Anna Ringler, Kseniya Khamina, Stefan Kubicek, Elizabeth P. Murchison, Benedikt Agerer, Peter Májek, Katja Parapatics, Richard Moriggl, Mark J. Smyth, Johanna Klughammer, Bojan Vilagos, Alexander Lercher, Hatoon Baazim, Elvin D. de Araujo, Siawash Ahmar
Publikováno v:
Cancer Cell
Summary The marsupial Tasmanian devil (Sarcophilus harrisii) faces extinction due to transmissible devil facial tumor disease (DFTD). To unveil the molecular underpinnings of this transmissible cancer, we combined pharmacological screens with an inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7956ef0b526be60c90a247b0e646665
https://eprints.soton.ac.uk/427459/
https://eprints.soton.ac.uk/427459/
Autor:
Nikolaus Krall, Judith Lafleur, Lukas Hefler, Michael Schumacher, Minichsdorfer Christoph, Gregory I. Vladimer, Florian Rohrer, Isabella Alt, Christina Taubert, Thorsten Füreder, Robert Sehlke, Bojan Vilagos, Klaus Hackner, Dominik Maurer, Elisabeth Fuchs
Publikováno v:
Cancer Research. 80:5233-5233
Introduction: A vast majority of investigational anticancer drugs found to be active in preclinical development later do not show the desired effect in the clinic (Wong et al., Biostatistics 2019). This suggests that currently used preclinical models
Autor:
Hatoon Baazim, Benedikt Agerer, Peter Májek, Patrick T. Gunning, Stefan Kubicek, Ji Sung Park, Johanna Klughammer, Hannah V. Siddle, Christoph Bock, Katja Parapatics, Elizabeth P. Murchison, Richard Moriggl, Mark J. Smyth, David A. Rosa, Bojan Vilagos, Kseniya Khamina, Lindsay Kosack, Andreas Bergthaler, Anna Ringler, Alexander Lercher, Keiryn L. Bennett, Anna Orlova, Bettina Wingelhofer, Alexandra Popa
SummaryThe marsupial Tasmanian devil (Sarcophilus harrisii) faces extinction due to transmissible devil facial tumor disease (DFTD). To unveil the molecular underpinnings of DFTD, we designed an approach that combines sensitivity to drugs with an int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177756c32100ff84bcc217481534fce2
https://doi.org/10.1101/283309
https://doi.org/10.1101/283309
Autor:
Lindsay Kosack, Riem Gawish, Alexander Lercher, Bojan Vilagos, Anastasiya Hladik, Karin Lakovits, Anannya Bhattacharya, Christopher Schliehe, Ildiko Mesteri, Sylvia Knapp, Andreas Bergthaler
Publikováno v:
Scientific Reports
Scientific Reports, 7:11289. Nature Publishing Group
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, 7:11289. Nature Publishing Group
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Lipid metabolism is increasingly being appreciated to affect immunoregulation, inflammation and pathology. In this study we found that mice infected with lymphocytic choriomeningitis virus (LCMV) exhibit global perturbations of circulating serum lipi