Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bojan Polic"'
Autor:
J Christoph Vahl, Klaus Heger, Nathalie Knies, Marco Y Hein, Louis Boon, Hideo Yagita, Bojan Polic, Marc Schmidt-Supprian
Publikováno v:
PLoS Biology, Vol 11, Iss 6, p e1001589 (2013)
Natural killer T (NKT) cell development depends on recognition of self-glycolipids via their semi-invariant Vα14i-TCR. However, to what extent TCR-mediated signals determine identity and function of mature NKT cells remains incompletely understood.
Externí odkaz:
https://doaj.org/article/14a587f06afd43f289a5c7ac5d266e91
Publikováno v:
Cells, Vol 13, Iss 17, p 1464 (2024)
Natural Killer (NK) cells, integral components of the innate immune system, play a crucial role in the protection against intracellular threats. Their cytotoxic power requires that activation is tightly controlled, and in this, they take a unique pos
Externí odkaz:
https://doaj.org/article/ba56723cc514464eab10cd640ac20e7c
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cells play an important role in the early defense against tumors and virally infected cells. Their function is thought to be controlled by the balance between activating and inhibitory receptors, which often compete for the same l
Externí odkaz:
https://doaj.org/article/3e500e3a98db444b83cf53a0f316a0b2
Autor:
Michael J, Taussig, Oda, Stoevesandt, Carl A K, Borrebaeck, Andrew R, Bradbury, Dolores, Cahill, Christian, Cambillau, Antoine, de Daruvar, Stefan, Dübel, Jutta, Eichler, Ronald, Frank, Toby J, Gibson, David, Gloriam, Larry, Gold, Friedrich W, Herberg, Henning, Hermjakob, Jörg D, Hoheisel, Thomas O, Joos, Olli, Kallioniemi, Manfred, Koegl, Manfred, Koegll, Zoltán, Konthur, Bernhard, Korn, Elisabeth, Kremmer, Sylvia, Krobitsch, Ulf, Landegren, Silvère, van der Maarel, John, McCafferty, Serge, Muyldermans, Per-Ake, Nygren, Sandrine, Palcy, Andreas, Plückthun, Bojan, Polic, Michael, Przybylski, Petri, Saviranta, Alan, Sawyer, David J, Sherman, Arne, Skerra, Markus, Templin, Marius, Ueffing, Mathias, Uhlén
Publikováno v:
Nature Methods
Nature Methods, Nature Publishing Group, 2007, 4, pp.13-17. ⟨10.1038/nmeth0107-13⟩
Taussig, M J, Stoevesandt, O, Borrebaeck, C A K, Kallioniemi, O, Saviranta, P & authors, E A 2007, ' ProteomeBinders : Planning a European resource of affinity reagents for analysis of the human proteome ', Nature Methods, vol. 4, pp. 13-17 . https://doi.org/10.1038/nmeth0107-13
Nature Methods, 2007, 4, pp.13-17. ⟨10.1038/nmeth0107-13⟩
Nature Methods, Nature Publishing Group, 2007, 4, pp.13-17. ⟨10.1038/nmeth0107-13⟩
Taussig, M J, Stoevesandt, O, Borrebaeck, C A K, Kallioniemi, O, Saviranta, P & authors, E A 2007, ' ProteomeBinders : Planning a European resource of affinity reagents for analysis of the human proteome ', Nature Methods, vol. 4, pp. 13-17 . https://doi.org/10.1038/nmeth0107-13
Nature Methods, 2007, 4, pp.13-17. ⟨10.1038/nmeth0107-13⟩
ProteomeBinders is a new European consortium aiming to establish a comprehensive resource of well-characterized affinity reagents, including but not limited to antibodies, for analysis of the human proteome. Given the huge diversity of the proteome,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2215f41e15937cacaffe2d86bcec98
https://hal.archives-ouvertes.fr/hal-00306585
https://hal.archives-ouvertes.fr/hal-00306585
Autor:
Mary Markiewicz, Saravanan Raju, Lena Kretzmer, Olivia Koues, Jacqueline Payton, Eugene Oltz, Amanda Cashen, Bojan Polic, Robert Schreiber, Andrey Shaw
Publikováno v:
The Journal of Immunology. 194:210.21-210.21
Transgenic mice we generated with ubiquitous expression of the NKG2D ligand RAE1ε, and therefore low surface NKG2D expression, developed natural, spontaneous B cell lymphoma at a younger age than wild-type mice. Transplantation of lymphomas from RAE
Publikováno v:
European journal of immunology. 32(12)
The expression of the preB cell receptor (preBCR), composed of the mu chain, surrogate light chains and the Igalpha /Igbeta signal transduction unit, permits further differentiation of Bcell precursors. C57BL/6 mice homozygous for an inactivating mut
Publikováno v:
Metabolites, Vol 13, Iss 2, p 153 (2023)
In their aspiration to become healthy, people are known to follow extreme diets. However, the acute impact on organs regulating systemic metabolism is not well characterized. Here, we investigated the acute impact of six extreme diets on the liver in
Externí odkaz:
https://doaj.org/article/dcab13eff39544748fbf1f929965714f
Autor:
Inga Kavazović, Hongya Han, Giulia Balzaretti, Erik Slinger, Niels A W Lemmermann, Anja Ten Brinke, Doron Merkler, Jan Koster, Yenan T Bryceson, Niek de Vries, Stipan Jonjić, Paul L Klarenbeek, Bojan Polić, Eric Eldering, Felix M Wensveen
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000648 (2020)
The memory CD8 T-cell pool must select for clones that bind immunodominant epitopes with high affinity to efficiently counter reinfection. At the same time, it must retain a level of clonal diversity to allow recognition of pathogens with mutated epi
Externí odkaz:
https://doaj.org/article/44f011a2567046b1a91de7cf857789c9
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Effector and memory CD8 T cells have an intrinsic difference in the way they must approach antigen; effector cells need to address the pathogen at hand and therefore favor outgrowth of only high-affinity clones. In contrast, the memory pool benefits
Externí odkaz:
https://doaj.org/article/aec619f1370949d48a2a8796e03f4b73
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
NKG2D is an activating receptor that is mostly expressed on cells of the cytotoxic arm of the immune system. Ligands of NKG2D are normally of low abundance, but can be induced in virtually any cell in response to stressors, such as infection and onco
Externí odkaz:
https://doaj.org/article/2d0b0e4da5b7482ca8be7b2de17673b6