Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Bojan Losic"'
Autor:
Navneet Dogra, Tzu‐Yi Chen, Edgar Gonzalez‐Kozlova, Rebecca Miceli, Carlos Cordon‐Cardo, Ashutosh K. Tewari, Bojan Losic, Gustavo Stolovitzky
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract From eukaryotes to prokaryotes, all cells secrete extracellular vesicles (EVs) as part of their regular homeostasis, intercellular communication, and cargo disposal. Accumulating evidence suggests that small EVs carry functional small RNAs,
Externí odkaz:
https://doaj.org/article/4eb2fcd54b804e91aa9bb4f880589ccf
Autor:
Lauren A. Peters, Joshua R. Friedman, Aleksandar Stojmirovic, Jacob Hagen, Sander Houten, Tetyana Dodatko, Mariana P. Amaro, Paula Restrepo, Zhi Chai, J. Rodrigo Mora, Holly A. Raymond, Mark Curran, Radu Dobrin, Anuk Das, Huabao Xiong, Eric E. Schadt, Carmen Argmann, Bojan Losic
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Longitudinal changes in gene expression, splicing patterns and adaptive immune repertoire in murine models of colitis are examined and associated with histologic inflammation in mice and in patients with inflammatory bowel disease.
Externí odkaz:
https://doaj.org/article/95a2a99b4f784d3c91deb9675e5c43a3
Autor:
Noam D. Beckmann, Phillip H. Comella, Esther Cheng, Lauren Lepow, Aviva G. Beckmann, Scott R. Tyler, Konstantinos Mouskas, Nicole W. Simons, Gabriel E. Hoffman, Nancy J. Francoeur, Diane Marie Del Valle, Gurpawan Kang, Anh Do, Emily Moya, Lillian Wilkins, Jessica Le Berichel, Christie Chang, Robert Marvin, Sharlene Calorossi, Alona Lansky, Laura Walker, Nancy Yi, Alex Yu, Jonathan Chung, Matthew Hartnett, Melody Eaton, Sandra Hatem, Hajra Jamal, Alara Akyatan, Alexandra Tabachnikova, Lora E. Liharska, Liam Cotter, Brian Fennessy, Akhil Vaid, Guillermo Barturen, Hardik Shah, Ying-chih Wang, Shwetha Hara Sridhar, Juan Soto, Swaroop Bose, Kent Madrid, Ethan Ellis, Elyze Merzier, Konstantinos Vlachos, Nataly Fishman, Manying Tin, Melissa Smith, Hui Xie, Manishkumar Patel, Kai Nie, Kimberly Argueta, Jocelyn Harris, Neha Karekar, Craig Batchelor, Jose Lacunza, Mahlet Yishak, Kevin Tuballes, Ieisha Scott, Arvind Kumar, Suraj Jaladanki, Charuta Agashe, Ryan Thompson, Evan Clark, Bojan Losic, Lauren Peters, The Mount Sinai COVID-19 Biobank Team, Panagiotis Roussos, Jun Zhu, Wenhui Wang, Andrew Kasarskis, Benjamin S. Glicksberg, Girish Nadkarni, Dusan Bogunovic, Cordelia Elaiho, Sandeep Gangadharan, George Ofori-Amanfo, Kasey Alesso-Carra, Kenan Onel, Karen M. Wilson, Carmen Argmann, Supinda Bunyavanich, Marta E. Alarcón-Riquelme, Thomas U. Marron, Adeeb Rahman, Seunghee Kim-Schulze, Sacha Gnjatic, Bruce D. Gelb, Miriam Merad, Robert Sebra, Eric E. Schadt, Alexander W. Charney
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Multisystem inflammatory syndrome in children (MIS-C) onsets in COVID-19 patients with manifestations similar to Kawasaki disease (KD). Here the author probe the peripheral blood transcriptome of MIS-C patients to find signatures related to natural k
Externí odkaz:
https://doaj.org/article/7233a40d610f443eac2e6011b12c9368
Autor:
Bojan Losic, Amanda J. Craig, Carlos Villacorta-Martin, Sebastiao N. Martins-Filho, Nicholas Akers, Xintong Chen, Mehmet E. Ahsen, Johann von Felden, Ismail Labgaa, Delia DʹAvola, Kimaada Allette, Sergio A. Lira, Glaucia C. Furtado, Teresa Garcia-Lezana, Paula Restrepo, Ashley Stueck, Stephen C. Ward, Maria I. Fiel, Spiros P. Hiotis, Ganesh Gunasekaran, Daniela Sia, Eric E. Schadt, Robert Sebra, Myron Schwartz, Josep M. Llovet, Swan Thung, Gustavo Stolovitzky, Augusto Villanueva
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Immune-mediated selection pressures impact the clonal evolution of tumours. Here, in hepatocellular carcinoma the authors map spatio-temporal interactions between tumor and immune cells, highlighting the regulatory substrate of intra-tumoural heterog
Externí odkaz:
https://doaj.org/article/b7e9387e6d0443a18b41f98ca9cd0d20
Autor:
Roger P. Alexander, Robert R Kitchen, Juan Pablo Tosar, Matthew Roth, Pieter Mestdagh, Klaas E. A. Max, Joel Rozowsky, Karolina Elżbieta Kaczor-Urbanowicz, Justin Chang, Leonora Balaj, Bojan Losic, Eric L. Van Nostrand, Emily LaPlante, Bogdan Mateescu, Brian S. White, Rongshan Yu, Aleksander Milosavljevic, Gustavo Stolovitzky, Ryan M. Spengler
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
We now know RNA can survive the harsh environment of biofluids when encapsulated in vesicles or by associating with lipoproteins or RNA binding proteins. These extracellular RNA (exRNA) play a role in intercellular signaling, serve as biomarkers of d
Externí odkaz:
https://doaj.org/article/d4209b9f34794e26b87ce77d73536889
Autor:
Amanda J Craig, Teresa Garcia-Lezana, Marina Ruiz de Galarreta, Carlos Villacorta-Martin, Edgar G Kozlova, Sebastiao N Martins-Filho, Johann von Felden, Mehmet Eren Ahsen, Erin Bresnahan, Gabriela Hernandez-Meza, Ismail Labgaa, Delia D'Avola, Myron Schwartz, Josep M Llovet, Daniela Sia, Swan Thung, Bojan Losic, Amaia Lujambio, Augusto Villanueva
Publikováno v:
PLoS Genetics, Vol 17, Iss 6, p e1009589 (2021)
Cancer testis antigens (CTAs) are an extensive gene family with a unique expression pattern restricted to germ cells, but aberrantly reactivated in cancer tissues. Studies indicate that the expression (or re-expression) of CTAs within the MAGE-A fami
Externí odkaz:
https://doaj.org/article/cc9f4cfb85bd4a1686eaa53fc84df178
Autor:
Adrian Bubie, Fabien Zoulim, Barbara Testoni, Brett Miles, Marshall Posner, Augusto Villanueva, Bojan Losic
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102368- (2021)
Summary: The role of oncoviral genotype and co-infection driving oncogenesis remains unclear. We have developed a scalable, high throughput tool for sensitive and precise oncoviral genotype deconvolution. Using tumor RNA sequencing data, we applied i
Externí odkaz:
https://doaj.org/article/fe79134d736e460da35b53867cbd1886
Autor:
Jennifer EL Diaz, Mehmet Eren Ahsen, Thomas Schaffter, Xintong Chen, Ronald B Realubit, Charles Karan, Andrea Califano, Bojan Losic, Gustavo Stolovitzky
Publikováno v:
eLife, Vol 9 (2020)
Our ability to discover effective drug combinations is limited, in part by insufficient understanding of how the transcriptional response of two monotherapies results in that of their combination. We analyzed matched time course RNAseq profiling of c
Externí odkaz:
https://doaj.org/article/665260e292954bb886f7e1e6728dbc27
Autor:
Huan Wang, Aaron Bender, Peng Wang, Esra Karakose, William B. Inabnet, Steven K. Libutti, Andrew Arnold, Luca Lambertini, Micheal Stang, Herbert Chen, Yumi Kasai, Milind Mahajan, Yayoi Kinoshita, Gustavo Fernandez-Ranvier, Thomas C. Becker, Karen K. Takane, Laura A. Walker, Shira Saul, Rong Chen, Donald K. Scott, Jorge Ferrer, Yevgeniy Antipin, Michael Donovan, Andrew V. Uzilov, Boris Reva, Eric E. Schadt, Bojan Losic, Carmen Argmann, Andrew F. Stewart
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Diabetes results in part from a deficiency of functional pancreatic beta cells. Here, the authors study the genomic and epigenetic landscapes of human insulinomas to gain insight into possible pathways for therapeutic beta cell regeneration, highligh
Externí odkaz:
https://doaj.org/article/80c3e45c47014686a61554de1f26c1c1
Autor:
Eduardo J Contijoch, Graham J Britton, Chao Yang, Ilaria Mogno, Zhihua Li, Ruby Ng, Sean R Llewellyn, Sheela Hira, Crystal Johnson, Keren M Rabinowitz, Revital Barkan, Iris Dotan, Robert P Hirten, Shih-Chen Fu, Yuying Luo, Nancy Yang, Tramy Luong, Philippe R Labrias, Sergio Lira, Inga Peter, Ari Grinspan, Jose C Clemente, Roman Kosoy, Seunghee Kim-Schulze, Xiaochen Qin, Anabella Castillo, Amanda Hurley, Ashish Atreja, Jason Rogers, Farah Fasihuddin, Merjona Saliaj, Amy Nolan, Pamela Reyes-Mercedes, Carina Rodriguez, Sarah Aly, Kenneth Santa-Cruz, Lauren Peters, Mayte Suárez-Fariñas, Ruiqi Huang, Ke Hao, Jun Zhu, Bin Zhang, Bojan Losic, Haritz Irizar, Won-Min Song, Antonio Di Narzo, Wenhui Wang, Benjamin L Cohen, Christopher DiMaio, David Greenwald, Steven Itzkowitz, Aimee Lucas, James Marion, Elana Maser, Ryan Ungaro, Steven Naymagon, Joshua Novak, Brijen Shah, Thomas Ullman, Peter Rubin, James George, Peter Legnani, Shannon E Telesco, Joshua R Friedman, Carrie Brodmerkel, Scott Plevy, Judy H Cho, Jean-Frederic Colombel, Eric E Schadt, Carmen Argmann, Marla Dubinsky, Andrew Kasarskis, Bruce Sands, Jeremiah J Faith
Publikováno v:
eLife, Vol 8 (2019)
To identify factors that regulate gut microbiota density and the impact of varied microbiota density on health, we assayed this fundamental ecosystem property in fecal samples across mammals, human disease, and therapeutic interventions. Physiologic
Externí odkaz:
https://doaj.org/article/0030eccfbbf04caa9643ee26d5af44c0