Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Boitelo T Letsolo"'
Autor:
Boitelo T Letsolo, Rhiannon E Jones, Jan Rowson, Julia W Grimstead, W Nicol Keith, Gareth J S Jenkins, Duncan M Baird
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174833 (2017)
Barrett's oesophagus is a premalignant metaplastic condition that predisposes patients to the development of oesophageal adenocarcinoma. However, only a minor fraction of Barrett's oesophagus patients progress to adenocarcinoma and it is thus essenti
Externí odkaz:
https://doaj.org/article/d8f9b80fd6ea4b6196df8cda58935a64
Autor:
Kerrilyn Naidoo, Sibusiso T Malindisa, Tyrone C Otgaar, Martin Bernert, Bianca Da Costa Dias, Eloise Ferreira, Uwe Reusch, Stefan Knackmuss, Melvyn Little, Stefan F T Weiss, Boitelo T Letsolo
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141618 (2015)
Cancer has become a major problem worldwide due to its increasing incidence and mortality rates. Both the 37kDa/67kDa laminin receptor (LRP/LR) and telomerase are overexpressed in cancer cells. LRP/LR enhances the invasiveness of cancer cells thereby
Externí odkaz:
https://doaj.org/article/9511088401f7480fba48e10fafe0c834
Autor:
Boitelo T. Letsolo, Nicolas Tagliatti, Katarina Jovanovic, Eloise Ferreira, Tyrone C. Otgaar, Stefan Weiss, Monique J Bignoux
Publikováno v:
Oncotarget. 9:27059-27073
Alzheimer's disease (AD) is a neurodegenerative disease caused by accumulation of amyloid beta (Aβ) plaque and neurofibrillary tangle formation. We have shown in vitro, that knock-down and blockade of the 37 kDa/67 kDa Laminin Receptor (LRP/LR) resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68927c57d4463d1d5043609c2872bb94
https://doi.org/10.18632/oncotarget.25473
https://doi.org/10.18632/oncotarget.25473
Autor:
Sibusiso T Malindisa, Martin Bernert, Boitelo T. Letsolo, Stefan Weiss, Eloise Ferreira, Tyrone C. Otgaar
Publikováno v:
Oncotarget
// Tyrone C. Otgaar 1 , Eloise Ferreira 1 , Sibusiso Malindisa 1, 2 , Martin Bernert 1 , Boitelo T. Letsolo 1 and Stefan F.T. Weiss 1 1 School of Molecular and Cell Biology, University of the Witwatersrand, Wits 2050, Republic of South Africa 2 Prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9f18319d9c595b314fb85c926ea171
http://europepmc.org/articles/PMC5689714
http://europepmc.org/articles/PMC5689714
Autor:
Monique J Bignoux, Stefan Weiss, Boitelo T. Letsolo, Eloise Ferreira, Tyrone C. Otgaar, Katelyn Cuttler
Publikováno v:
Journal of Alzheimer's disease : JAD. 69(3)
Alzheimer's disease (AD) represents the most common form of neurodegenerative disorders with only palliative treatments currently available. Amyloid plaque formation caused by amyloid-β (Aβ) aggregation and neurofibrillary tangle formation caused b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62b6104ffa258884a1e3371550e0d7c
https://pubmed.ncbi.nlm.nih.gov/31081791
https://pubmed.ncbi.nlm.nih.gov/31081791
Publikováno v:
Head & Neck. 38:417-425
BACKGROUND: Among head and neck cancers, human papillomavirus type 16 (HPV16) is associated with tonsillar carcinomas. Despite this, no HPV16-positive tonsillar cancer cell line has been established in nude mice.METHODS: Fresh tonsillar carcinoma bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4f7b351a1cef0573fbc9a2a326d5e02
https://doi.org/10.1002/hed.23918
https://doi.org/10.1002/hed.23918
Autor:
Sibusiso T Malindisa, Boitelo T. Letsolo, Bianca Da Costa Dias, Thandokuhle Khumalo, Carryn J. Chetty, Stefan Weiss, Robert Caveney, Eloise Ferreira, Katarina Jovanovic
Publikováno v:
Expert Opinion on Therapeutic Patents. 25:567-582
The 37/67 kDa high-affinity laminin receptor (laminin receptor precursor/laminin receptor, LRP/LR) is a multi-faceted cellular receptor. It plays a vital role in the malignancy of various cancer types where it is seen to contribute to invasion, adhes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1ea0275aa879d92b729684418ceee6
https://doi.org/10.1517/13543776.2015.1014802
https://doi.org/10.1517/13543776.2015.1014802
Autor:
Boitelo T, Letsolo, Rhiannon E, Jones, Jan, Rowson, Julia W, Grimstead, W Nicol, Keith, Gareth J S, Jenkins, Duncan M, Baird
Publikováno v:
PLoS ONE
Barrett’s oesophagus is a premalignant metaplastic condition that predisposes patients to the development of oesophageal adenocarcinoma. However, only a minor fraction of Barrett’s oesophagus patients progress to adenocarcinoma and it is thus ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::269a4d630632a48410de2c28ea65acea
https://pubmed.ncbi.nlm.nih.gov/28362812
https://pubmed.ncbi.nlm.nih.gov/28362812
Autor:
Rebecca Capper, A. Malcolm R. Taylor, Bethan Britt-Compton, Rhiannon E. Jones, Boitelo T. Letsolo, Duncan M. Baird, Maira Tankimanova, Jan Rowson
Publikováno v:
Nucleic Acids Research
The loss of telomere function can result in the fusion of telomeres with other telomeric loci, or non-telomeric double-stranded DNA breaks. Sequence analysis of fusion events between short dysfunctional telomeres in human cells has revealed that fusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3475e85a7200a67a55241691de56104
http://europepmc.org/articles/PMC3315324
http://europepmc.org/articles/PMC3315324
Autor:
Rhiannon E. Jones, Christopher Fegan, Saman Hewamana, Duncan M. Baird, Thet Thet Lin, Guy Pratt, Chris Pepper, Boitelo T. Letsolo, Jan Rowson
Publikováno v:
Blood. 116:1899-1907
We performed single-molecule telomere length and telomere fusion analysis in patients at different stages of chronic lymphocytic leukemia (CLL). Our work identified the shortest telomeres ever recorded in primary human tissue, reinforcing the concept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014a389d4b03c6dba2c00fa8571d4655
https://doi.org/10.1182/blood-2010-02-272104
https://doi.org/10.1182/blood-2010-02-272104