Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bohumil Fafílek"'
Autor:
Vladimira Zlinska, Zuzana Feketova, Aleksandra Czyrek, Julia Chudzian, Martina Lenarcic Zivkovic, Vlad-Constantin Ursachi, Pooja Dudeja, Bohumil Fafilek, Jan Rynes, Gustavo Rico-Llanos, Adolf Koudelka, Tanaya Roy, Martyna Biadun, Vendula Raskova, Katerina Svozilova, Michaela Stroblova, Mateusz Krzyscik, Kalina Hristova, Daniel Krowarsch, Silvie Foldynova-Trantirkova, Malgorzata Zakrzewska, Lukas Trantirek, Pavel Krejci
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 36, Iss 1, Pp 102405- (2025)
Impaired fibroblast growth factor receptor (FGFR) signaling is associated with many human conditions, including growth disorders, degenerative diseases, and cancer. Current FGFR therapeutics are based on chemical inhibitors of FGFR tyrosine kinase ac
Externí odkaz:
https://doaj.org/article/ad06bb25575b42c4981efaaf0a6ec8c5
Autor:
Kelly Karl, Nuala Del Piccolo, Taylor Light, Tanaya Roy, Pooja Dudeja, Vlad-Constantin Ursachi, Bohumil Fafilek, Pavel Krejci, Kalina Hristova
Publikováno v:
eLife, Vol 12 (2024)
The differential signaling of multiple FGF ligands through a single fibroblast growth factor (FGF) receptor (FGFR) plays an important role in embryonic development. Here, we use quantitative biophysical tools to uncover the mechanism behind differenc
Externí odkaz:
https://doaj.org/article/59cd46cf169246dd8f9d3ba3c0045635
Autor:
Iva Gudernova, Silvie Foldynova-Trantirkova, Barbora El Ghannamova, Bohumil Fafilek, Miroslav Varecha, Lukas Balek, Eva Hruba, Lucie Jonatova, Iva Jelinkova, Michaela Kunova Bosakova, Lukas Trantirek, Jiri Mayer, Pavel Krejci
Publikováno v:
eLife, Vol 6 (2017)
In-cell profiling enables the evaluation of receptor tyrosine activity in a complex environment of regulatory networks that affect signal initiation, propagation and feedback. We used FGF-receptor signaling to identify EGR1 as a locus that strongly r
Externí odkaz:
https://doaj.org/article/163ec228390542f9aefa419a66246f0b
Autor:
Kamila Weissová, Bohumil Fafílek, Tomasz Radaszkiewicz, Canan Celiker, Petra Macháčková, Tamara Čechová, Jana Šebestíková, Aleš Hampl, Vítězslav Bryja, Pavel Krejčí, Tomáš Bárta
Luciferase reporter assays represent a simple and sensitive experimental system in cell and molecular biology to study multiple biological processes. However, the application of these assays is often limited by the costs of conventional luminometer i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::494d516b90efc1cf196db092156506c9
https://doi.org/10.1101/2022.01.28.478134
https://doi.org/10.1101/2022.01.28.478134
