Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Bohu Pan"'
Autor:
Binsheng Gong, Dan Li, Paweł P. Łabaj, Bohu Pan, Natalia Novoradovskaya, Danielle Thierry-Mieg, Jean Thierry-Mieg, Guangchun Chen, Anne Bergstrom Lucas, Jennifer S. LoCoco, Todd A. Richmond, Elizabeth Tseng, Rebecca Kusko, Scott Happe, Timothy R. Mercer, Carlos Pabón-Peña, Michael Salmans, Hagen U. Tilgner, Wenzhong Xiao, Donald J. Johann, Wendell Jones, Weida Tong, Christopher E. Mason, David P. Kreil, Joshua Xu
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-13 (2024)
Abstract Next-generation sequencing (NGS) has revolutionized genomic research by enabling high-throughput, cost-effective genome and transcriptome sequencing accelerating personalized medicine for complex diseases, including cancer. Whole genome/tran
Externí odkaz:
https://doaj.org/article/73cc5c3ee70441e7acfa9bce7c026093
Autor:
Bohu Pan, Luyao Ren, Vitor Onuchic, Meijian Guan, Rebecca Kusko, Steve Bruinsma, Len Trigg, Andreas Scherer, Baitang Ning, Chaoyang Zhang, Christine Glidewell-Kenney, Chunlin Xiao, Eric Donaldson, Fritz J. Sedlazeck, Gary Schroth, Gokhan Yavas, Haiying Grunenwald, Haodong Chen, Heather Meinholz, Joe Meehan, Jing Wang, Jingcheng Yang, Jonathan Foox, Jun Shang, Kelci Miclaus, Lianhua Dong, Leming Shi, Marghoob Mohiyuddin, Mehdi Pirooznia, Ping Gong, Rooz Golshani, Russ Wolfinger, Samir Lababidi, Sayed Mohammad Ebrahim Sahraeian, Steve Sherry, Tao Han, Tao Chen, Tieliu Shi, Wanwan Hou, Weigong Ge, Wen Zou, Wenjing Guo, Wenjun Bao, Wenzhong Xiao, Xiaohui Fan, Yoichi Gondo, Ying Yu, Yongmei Zhao, Zhenqiang Su, Zhichao Liu, Weida Tong, Wenming Xiao, Justin M. Zook, Yuanting Zheng, Huixiao Hong
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-26 (2022)
Abstract Background Reproducible detection of inherited variants with whole genome sequencing (WGS) is vital for the implementation of precision medicine and is a complicated process in which each step affects variant call quality. Systematically ass
Externí odkaz:
https://doaj.org/article/a888ae17e58a4cf188efc452ccec0462
Autor:
Michael M. Khayat, Sayed Mohammad Ebrahim Sahraeian, Samantha Zarate, Andrew Carroll, Huixiao Hong, Bohu Pan, Leming Shi, Richard A. Gibbs, Marghoob Mohiyuddin, Yuanting Zheng, Fritz J. Sedlazeck
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background Genomic structural variations (SV) are important determinants of genotypic and phenotypic changes in many organisms. However, the detection of SV from next-generation sequencing data remains challenging. Results In this study, DNA
Externí odkaz:
https://doaj.org/article/0f705634bb9d4e6ebe2949ac7601e5f7
Autor:
Wenjing Guo, Bohu Pan, Sugunadevi Sakkiah, Zuowei Ji, Gokhan Yavas, Yanhui Lu, Takashi E. Komatsu, Madhu Lal-Nag, Weida Tong, Tucker A. Patterson, Huixiao Hong
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Coronavirus disease 2019 (COVID-19) is an ongoing pandemic and there is an urgent need for safe and effective drugs for COVID-19 treatment. Since developing a new drug is time consuming, many approved or investigational drugs have been repur
Externí odkaz:
https://doaj.org/article/cec1715e9fd24f53a1ff4e77983d08f9
Autor:
Bohu Pan, Rebecca Kusko, Wenming Xiao, Yuanting Zheng, Zhichao Liu, Chunlin Xiao, Sugunadevi Sakkiah, Wenjing Guo, Ping Gong, Chaoyang Zhang, Weigong Ge, Leming Shi, Weida Tong, Huixiao Hong
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S2, Pp 17-29 (2019)
Abstract Background Reference genome selection is a prerequisite for successful analysis of next generation sequencing (NGS) data. Current practice employs one of the two most recent human reference genome versions: HG19 or HG38. To date, the impact
Externí odkaz:
https://doaj.org/article/49310cbfb8a84d8296ccb15718252750
Autor:
Sugunadevi Sakkiah, Wenjing Guo, Bohu Pan, Zuowei Ji, Gokhan Yavas, Marli Azevedo, Jessica Hawes, Tucker A. Patterson, Huixiao Hong
Publikováno v:
Frontiers in Chemistry, Vol 8 (2021)
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). As of October 21, 2020, more than 41.4 million confirmed cases and 1.1 million deaths have been reported. Thus, it is immensely important to deve
Externí odkaz:
https://doaj.org/article/35a8253bc1184e148cec3ee6108bfd3a
Autor:
Bohu Pan, Zuowei Ji, Sugunadevi Sakkiah, Wenjing Guo, Jie Liu, Tucker A. Patterson, Huixiao Hong
Publikováno v:
Viruses, Vol 13, Iss 5, p 764 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS−CoV−2) has caused the ongoing global COVID-19 pandemic that began in late December 2019. The rapid spread of SARS−CoV−2 is primarily due to person-to-person transmission. To understand the
Externí odkaz:
https://doaj.org/article/4e0aed18cf5941358bbabbabd27ccaf4
Autor:
Sugunadevi Sakkiah, Rebecca Kusko, Bohu Pan, Wenjing Guo, Weigong Ge, Weida Tong, Huixiao Hong
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
When a small molecule binds to the androgen receptor (AR), a conformational change can occur which impacts subsequent binding of co-regulator proteins and DNA. In order to accurately study this mechanism, the scientific community needs a crystal stru
Externí odkaz:
https://doaj.org/article/8205112e8e1c41a4baf1f4722ddcc68c
Autor:
Bohu Pan, Rebecca Kusko, Wenming Xiao, Yuanting Zheng, Zhichao Liu, Chunlin Xiao, Sugunadevi Sakkiah, Wenjing Guo, Ping Gong, Chaoyang Zhang, Weigong Ge, Leming Shi, Weida Tong, Huixiao Hong
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-1 (2019)
After publication of this supplement article
Externí odkaz:
https://doaj.org/article/392fe08224784663805487eb829125c1
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006191 (2016)
The hydrolytic deamination of adenosine to inosine (A-to-I editing) in precursor mRNA induces variable gene products at the post-transcription level. How and to what extent A-to-I RNA editing diversifies transcriptome is not fully characterized in th
Externí odkaz:
https://doaj.org/article/dae7f479175a4c70bcfe176806a99e10