Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Bohong Cen"'
Autor:
Cuiying Xie, Ancheng Gu, Muhammad Khan, Xiangcao Yao, Leping Chen, Jiali He, Fumiao Yuan, Ping Wang, Yufan Yang, Yerong Wei, Fang Tang, Hualong Su, Jiamin Chen, Jinxia Li, Bohong Cen, Zhongyuan Xu
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Hepatocellular carcinoma is one of the malignancies worldwide with a high mortality rate and an increasing incidence. Molecular Targeted agents are its common first-line treatment. Organoid technology, as a cutting-edge technology, is gradually being
Externí odkaz:
https://doaj.org/article/a95aaab6c4234d979c64a25e4c1af3fd
Autor:
Lumin Liao, Bohong Cen, Guoxian Li, Yuanyi Wei, Zhen Wang, Wen Huang, Shuai He, Yawei Yuan, Aimin Ji
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 1432-1442 (2021)
The vascular endothelial growth factor receptor 2 (VEGFR2) is considered to be a pivotal target for anti-tumor therapy against angiogenesis of non-small cell lung cancer (NSCLC). However, effective and low-toxicity targeted therapies to inhibit VEGFR
Externí odkaz:
https://doaj.org/article/f43b7a7a76bb41d4b1c1ce9774b7c916
Autor:
Zili Dai, Taisheng Liu, Guihong Liu, Zhen Deng, Peng Yu, Baiyao Wang, Bohong Cen, Liyi Guo, Jian Zhang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Background: Lung cancer is the leading cause of cancer-related death globally. Hypoxia can suppress the activation of the tumor microenvironment (TME), which contributes to distant metastasis. However, the role of hypoxia-mediated TME in predicting t
Externí odkaz:
https://doaj.org/article/114a8744e5144248b237874bfbd8e4ef
Autor:
Jian Zhang, Huali Jiang, Kunpeng Du, Tao Xie, Baiyao Wang, Chengcong Chen, Bohong Cen, Yawei Yuan, Jiacai Ye
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: Cancer patients are alleged to have poor coronavirus disease 2019 (COVID-19) outcomes. However, no systematic or comprehensive analyses of the role and mechanisms of COVID-19 receptor-related regulators in cancer are available.Methods: We
Externí odkaz:
https://doaj.org/article/fa08a9d5838648dfb298254d01b1bde4
Autor:
Bohong Cen, Yuanyi Wei, Wen Huang, Muzhou Teng, Shuai He, Jianlong Li, Wei Wang, Guolin He, Xin Bai, Xiaoxia Liu, Yawei Yuan, Xinghua Pan, Aimin Ji
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 220-232 (2018)
The PI3K-AKT-mTOR-signaling pathway is frequently activated in glioblastoma (GBM). Inhibition of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta (PIK3CB)/p110β (a PI3K catalytic isoform) by RNAi substantially suppresses GBM gro
Externí odkaz:
https://doaj.org/article/a64c112b0f8e48d3b7e3542fd841ec7c
Autor:
Wenjie Liao, Yixin Qin, Lumin Liao, Bohong Cen, Zhuomin Wu, Yuanyi Wei, Zhen Wang, Guoxian Li, Aimin Ji
Publikováno v:
Renal Failure, Vol 40, Iss 1, Pp 187-195 (2018)
Based on successful targeting to the αvβ3 integrin of cyclic arginine–glycine–aspartic acid (cRGD), cRGD-conjugated small interfering RNA (siRNA) exhibits tumor targeting and has become a new treatment strategy for solid tumors. However, the ne
Externí odkaz:
https://doaj.org/article/f3325607d04f486fb8cd09fbc6970724
Autor:
Bohong Cen, Wenjie Liao, Zhen Wang, Linyuan Gao, Yuanyi Wei, Wen Huang, Shuai He, Wei Wang, Xiaoxia Liu, Xinghua Pan, Aimin Ji
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 11, Iss C, Pp 300-311 (2018)
Integrin αvβ3, which is selectively targeted by cyclic arginine-glycine-aspartic acid (cRGD) peptides, is significantly upregulated in tumors. Previous studies showed that small interfering RNA (siRNA) modified with cRGD (cRGD-siRNA) could signific
Externí odkaz:
https://doaj.org/article/db65875f11f940e481719549dc8a9f5b
Autor:
Shuai He, Bohong Cen, Lumin Liao, Zhen Wang, Yixin Qin, Zhuomin Wu, Wenjie Liao, Zhongyi Zhang, Aimin Ji
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 471-481 (2017)
The epidermal growth factor receptor (EGFR) is an important anti-tumor target. The development of novel molecular-targeted anti-tumor drugs that can target the interior of tumor cells and specifically silence EGFR expression is valuable and promising
Externí odkaz:
https://doaj.org/article/24767c86621d4f3299ff3192454c7401
Autor:
Yunhong Tian, Meiling Ai, Chunshan Liu, Yuchao Wu, Muhammad Khan, Baiyao Wang, Huidong Long, Chunyue Huang, Jie Lin, Anan Xu, Rong Li, Bohong Cen, Wenze Qiu, Guofeng Xie, Yawei Yuan
Publikováno v:
International Journal of Biological Sciences. 19:2349-2365
Autor:
Baiyao Wang, Wei Liu, Chunshan Liu, Kunpeng Du, Zhaoze Guo, Guoqian Zhang, Zhong Huang, Shuhui Lin, Bohong Cen, Yunhong Tian, Yawei Yuan, Junguo Bu
Publikováno v:
International journal of radiation oncology, biology, physics.
Cancer-associated fibroblasts (CAFs) are an integral part of the tumor microenvironment (TME), which is involved in the therapy resistance. Here, we aimed to investigate the role of CAFs in radiosensitivity of breast cancer cells.The CAFs were isolat