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Autor:
Bohn, Manfred, Heermann, Dieter W.
Chromatin looping is a major epigenetic regulatory mechanism in higher eukaryotes. Besides its role in transcriptional regulation, chromatin loops have been proposed to play a pivotal role in the segregation of entire chromosomes. The detailed topolo
Externí odkaz:
http://arxiv.org/abs/1001.4246
Autor:
Bohn, Manfred, Heermann, Dieter W.
Publikováno v:
Journal of Chemical Physics 130, 174901 (2009) http://link.aip.org/link/?JCPSA6/130/174901/1
Monte Carlo simulations of coarse-grained polymers provide a useful tool to deepen the understanding of conformational and statistical properties of polymers both in physical as well as in biological systems. In this study we sample compact conformat
Externí odkaz:
http://arxiv.org/abs/0905.0798
Autor:
Mateos-Langerak, Julio, Giromus, Osdilly, de Leeuw, Wim, Bohn, Manfred, Verschure, Pernette J., Kreth, Gregor, Heermann, Dieter W., van Driel, Roel, Goetze, Sandra
Three-dimensional (3D) chromatin structure is closely related to genome function, in particular transcription. However, the folding path of the chromatin fiber in the interphase nucleus is unknown. Here, we systematically measured the 3D physical dis
Externí odkaz:
http://arxiv.org/abs/0705.1656
Publikováno v:
Phys. Ref. E (76) 051805, 2007
While the structure of chromatin has been studied in great detail on length scales below 30 nm, amazingly little is known about the higher-order folding motifs of chromatin in interphase. Recent experiments give evidence that the folding may depend l
Externí odkaz:
http://arxiv.org/abs/0705.1470
Autor:
Heermann, Dieter W., Bohn, Manfred
We define a class of random matrix ensembles that pertain to random looped polymers. Such random looped polymers are a possible model for bio-polymers such as chromatin in the cell nucleus. It is shown that the distribution of the largest eigenvalue
Externí odkaz:
http://arxiv.org/abs/0705.1241
Publikováno v:
In Polymer Testing July 2015 44:1-7
Autor:
Bohn, Manfred
To improve its crystalline quality RDX is processed in suitable solvents; among them are cyclohexanone and gamma-butyrolactone. In spite of its relatively high thermal stability RDX can decompose to a certain extend during processing. Several qualiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad1354df9ed02504573bc801ea0dbad
Autor:
Mateos-Langerak, Julio, Bohn, Manfred, de Leeuw, Wim, Giromus, Osdilly, Manders, Erik M. M., Verschure, Pernette J., Indemans, Mireille H. G., Gierman, Hinco J., Heermann, Dieter W., van Driel, Roel, Goetze, Sandra, Rine, Jasper
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2009 Mar 01. 106(10), 3812-3817.
Externí odkaz:
https://www.jstor.org/stable/40428457