Výsledky vyhledávání - "Bohdana Hruskova"

Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice

Autor: Linn Amanda Syding, Agnieszka Kubik-Zahorodna, David Pajuelo Reguera, Petr Nickl, Bohdana Hruskova, Michaela Kralikova, Jana Kopkanova, Vendula Novosadova, Petr Kasparek, Jan Prochazka, Jan Rozman, Rostislav Turecek, Radislav Sedlacek

Publikováno v: Genes
Volume 14
Issue 2
Pages: 285

Stress responses are activated by the hypothalamic-pituitary-adrenal axis (HPA axis), culminating in the release of glucocorticoids. During prolonged periods of secretion of glucocorticoids or inappropriate behavioral responses to a stressor, patholo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c50a15477e4f80de537c66f8eb9d1f

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Cochlear ablation in neonatal rats disrupts inhibitory transmission in the medial nucleus of the trapezoid body

Autor: Stepanka Suchankova, Adolf Melichar, Johana Trojanova, Jolana Bartosova, Rostislav Turecek, Michaela Kralikova, Jana Burianová, Bohdana Hruskova, Jiri Popelar, Josef Syka

Publikováno v: Neuroscience Letters. 699:145-150

Inhibitory circuits in the auditory brainstem undergo multiple postnatal changes that are both activity-dependent and activity-independent. We tested to see if the shift from GABA- to glycinergic transmission, which occurs in the rat medial nucleus o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f931fd22f30928c01d796e99e64d59f0
https://doi.org/10.1016/j.neulet.2019.01.058

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Modulation of synaptic depression of the calyx of Held synapse by GABABreceptors and spontaneous activity

Autor: Tiantian Wang, Rostislav Turecek, Silviu I. Rusu, J. Gerard G. Borst, Bohdana Hruskova

Publikováno v: The Journal of Physiology. 591:4877-4894

The calyx of Held synapse of the medial nucleus of the trapezoid body is a giant axosomatic synapse in the auditory brainstem, which acts as a relay synapse showing little dependence of its synaptic strength on firing frequency. The main mechanism th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a50b29ddda10349e6b65bc241acdc12
https://doi.org/10.1113/jphysiol.2013.256875

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Akademický článek

The role of GABAB receptors in the subcortical pathways of the mammalian auditory system

Autor: Rostislav Tureček, Adolf Melichar, Michaela Králíková, Bohdana Hrušková

Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)

GABAB receptors are G-protein coupled receptors for the inhibitory neurotransmitter GABA. Functional GABAB receptors are formed as heteromers of GABAB1 and GABAB2 subunits, which further associate with various regulatory and signaling proteins to pro

Externí odkaz: https://doaj.org/article/1b7ba2d3a75b4d50903e3aaab004f1c1

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Modulation of synaptic depression of the calyx of Held synapse by GABA(B) receptors and spontaneous activity

Autor: Tiantian, Wang, Silviu I, Rusu, Bohdana, Hruskova, Rostislav, Turecek, J Gerard G, Borst

Publikováno v: The Journal of physiology. 591(19)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d230b28de45e3deaabe20b1b3257d4b0
https://pubmed.ncbi.nlm.nih.gov/23940376

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Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse

Autor: Josef Syka, Rostislav Turecek, Zbynek Bures, Michaela Kralikova, Johana Trojanova, Kateryna Pysanenko, Laurence O. Trussell, Bohdana Hruskova, Akos Kulik

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(47)

The properties of glycine receptors (GlyRs) depend upon their subunit composition. While the prevalent adult forms of GlyRs are heteromers, previous reports suggested functional α homomeric receptors in mature nervous tissues. Here we show two funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22cc6221f5852586fc6c584194b46ca
https://pubmed.ncbi.nlm.nih.gov/23175852

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Surface expression of metabotropic glutamate receptor variants mGluR1a and mGluR1b in transfected HEK293 cells

Autor: Michaela Kralikova, Daniela Franková, Lenka Kulihova, Bohdana Hruskova, Jean-Philippe Pin, Jaroslav Blahos, Laurent Prézeau, Zdenka Syrova, Jiri Kumpost, Veronika Hlavackova, Jean-Charles Bologna

Publikováno v: Neuropharmacology
Neuropharmacology, Elsevier, 2008, 55 (4), pp.409-18. ⟨10.1016/j.neuropharm.2008.06.073⟩
Neuropharmacology, 2008, 55 (4), pp.409-18. ⟨10.1016/j.neuropharm.2008.06.073⟩

International audience; Class C G-protein coupled receptors form obligatory dimers. Metabotropic glutamate receptors (mGluRs) are found commonly as homodimers. Alternative splicing of mGluR1 gene results in vivo in the expression of a long variant mG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4171c107cd75d284161b339c8e472df
https://pubmed.ncbi.nlm.nih.gov/18627772

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The second intracellular loop of metabotropic glutamate receptors recognizes C termini of G-protein alpha-subunits

Autor: Laurent Prézeau, Bohdana Hruskova, Michaela Havlickova, Jean-Philippe Pin, Jianfeng Liu, Jaroslav Blahos, Isabelle Brabet

Publikováno v: The Journal of biological chemistry. 278(37)

Heptahelical receptor coupling selectivity to G-proteins is controlled by a large contact area that involves several portions of the receptor and each subunit of the G-protein. In the G-protein alpha subunit, the C-terminal 5 residues, the N terminus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ec7df5ad46b12ddc65909440ca10fb
https://pubmed.ncbi.nlm.nih.gov/12829705

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