Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Bohao Zheng"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Nasopharyngeal carcinoma (NPC) arises from the mucosal epithelium of the nasopharynx and is frequently located in the pharyngeal crypts. This is a highly aggressive malignant tumor that frequently leads to distant metastases in many cases an
Externí odkaz:
https://doaj.org/article/eb194e0384514dc5bc14de01a91393d7
Publikováno v:
Cancer Medicine, Vol 13, Iss 17, Pp n/a-n/a (2024)
Abstract Background T cells, the “superstar” of the immune system, play a crucial role in antitumor immunity. T‐cell receptors (TCR) are crucial molecules that enable T cells to identify antigens and start immunological responses. The body has
Externí odkaz:
https://doaj.org/article/a633a63133824276afef1ae9e699d442
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Ferroptosis is an iron-dependent form of cell death, distinct from apoptosis, necrosis, and autophagy, and is characterized by altered iron homeostasis, reduced defense against oxidative stress, and increased lipid peroxidation. Extensive research ha
Externí odkaz:
https://doaj.org/article/5b1b03c1466946ae84a64f294f577a26
Autor:
Ying Tao, Zijun Gong, Sheng Shen, Yaqi Ding, Rui Zan, Bohao Zheng, Wentao Sun, Chaolin Ma, Mengxuan Shu, Xiao Lu, Han Liu, Xiaoling Ni, Houbao Liu, Tao Suo
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109659- (2024)
Summary: Abnormal mTORC1 activation by the lysosomal Ragulator complex has been implicated in cancer and glycolytic metabolism associated with drug resistance. Fasting upregulates RNF152 and mediates the metabolic status of cells. We report that RNF1
Externí odkaz:
https://doaj.org/article/872b1b7ef7e9435892f290aac909d983
Autor:
Dian Fan, Xu Wang, Zhixian Shi, Yuting Jiang, Bohao Zheng, Lian Xu, Shengtao Zhou, Yanjie Yin
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 16, Pp 1897-1909 (2023)
Abstract. Endometriosis, a heterogeneous, inflammatory, and estrogen-dependent gynecological disease defined by the presence and growth of endometrial tissues outside the lining of the uterus, affects approximately 5-10% of reproductive-age women, ca
Externí odkaz:
https://doaj.org/article/3cd05eac80f6480daea6d2c354027bea
Autor:
Rui Zan, Sheng Shen, Yuanding Huang, Han Yu, Yaohui Liu, Shi Yang, Bohao Zheng, Zijun Gong, Wenhui Wang, Xiaonong Zhang, Tao Suo, Houbao Liu
Publikováno v:
Smart Materials in Medicine, Vol 4, Iss , Pp 468-479 (2023)
With the increasing demand for innovative therapies, biodegradable magnesium has attracted more and more attention, which could avoid secondary surgery and reduce complications. Until now, plenty of researchers take part in the research & development
Externí odkaz:
https://doaj.org/article/c0de223486164dfa933b5a6f24d5c7e6
Autor:
Chunbin Zhu, Jiaqiang Ma, Kai Zhu, Lei Yu, Bohao Zheng, Dongning Rao, Shu Zhang, Liangqing Dong, Qiang Gao, Xiaoming Zhang, Diyang Xie
Publikováno v:
JHEP Reports, Vol 5, Iss 8, Pp 100762- (2023)
Background & Aims: Intrahepatic cholangiocarcinoma (iCCA) is a severe malignant tumour that shows only modest responses to immunotherapy. We aimed to identify the spatial immunophenotypes of iCCA and delineate potential immune escape mechanisms. Meth
Externí odkaz:
https://doaj.org/article/f654bb256f534edeb81a5051b62f2baf
Autor:
Kun Fan, Xiaojian Ni, Sheng Shen, Zijun Gong, Jiwen Wang, Yanlei Xin, Bohao Zheng, Wentao Sun, Han Liu, Tao Suo, Xiaoling Ni, Houbao Liu
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Gallbladder cancer is the most common biliary tract malignant tumor with highly metastatic characters and poor prognosis. However, the underlying mechanism remains unclear. Stathmin1 is ubiquitous phosphoprotein, regulating microtubule stabi
Externí odkaz:
https://doaj.org/article/c91d4000faca46798a4d4fa3f3cc3b10
Autor:
Xin Lian, Kailin Yang, Renliang Li, Maomao Li, Jing Zuo, Bohao Zheng, Wei Wang, Ping Wang, Shengtao Zhou
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract Cellular metabolism constitutes a fundamental process in biology. During tumor initiation and progression, each cellular component in the cancerous niche undergoes dramatic metabolic reprogramming, adapting to a challenging microenvironment
Externí odkaz:
https://doaj.org/article/acc18aa5c61848dc874f23b74c45c35d
Autor:
Jing Zuo, Zhe Zhang, Maomao Li, Yun Yang, Bohao Zheng, Ping Wang, Canhua Huang, Shengtao Zhou
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract Oxidative stress (OS), characterized by the excessive accumulation of reactive oxygen species (ROS), is an emerging hallmark of cancer. Tumorigenesis and development driven by ROS require an aberrant redox homeostasis, that activates onco-si
Externí odkaz:
https://doaj.org/article/7250b4a86ea649c5bf4ddbc65eb81b97