Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Boh-Ram Kim"'
Publikováno v:
Biomolecules & Therapeutics. 31:330-339
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1902993b5807826c5a05f6a334526155
https://doi.org/10.4062/biomolther.2023.041
https://doi.org/10.4062/biomolther.2023.041
Publikováno v:
Biomolecules & Therapeutics. 30:593-602
The human papillomavirus (HPV)-18 E7 (E7) oncoprotein is a major transforming protein that is thought to be involved in the development of cervical cancer. It is well-known that E7 stimulates tumour development by inactivating pRb. However, this alon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51a11986e432ec52d8e8a8773738247
https://doi.org/10.4062/biomolther.2022.108
https://doi.org/10.4062/biomolther.2022.108
Publikováno v:
Biomolecules & Therapeutics
Metformin is an anti-diabetic drug and has anticancer effects on various cancers. Several studies have suggested that metformin reduces cell proliferation and stimulates cell-cycle arrest and apoptosis. However, the definitive molecular mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6f6779650857d0cd1843bedc4fb9a7
https://doi.org/10.4062/biomolther.2021.131
https://doi.org/10.4062/biomolther.2021.131
Publikováno v:
Biomolecules & Therapeutics
The imprinted tumour suppressor NOEY2 is downregulated in various cancer types, including ovarian cancers. Recent data suggest that NOEY2 plays an essential role in regulating the cell cycle, angiogenesis and autophagy in tumorigenesis. However, its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a753ad885f4ef8d18a736d58b91ebce6
http://europepmc.org/articles/PMC8411030
http://europepmc.org/articles/PMC8411030
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7622, p 7622 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences
Volume 21
Issue 20
HPV16 E6 oncoprotein is a member of the human papillomavirus (HPV) family that contributes to enhanced cellular proliferation and risk of cervical cancer progression via viral infection. In this study, interferon regulatory factor-1 (IRF-1) regulates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197e77f553c5ee802ff131ebded036a0
https://www.mdpi.com/1422-0067/21/20/7622
https://www.mdpi.com/1422-0067/21/20/7622
Autor:
Hyun-Ji Kim, Ji-Yeon Lee, Seung Bae Rho, Ik Soon Jang, Min-Gwan Shin, Min-Ji Cho, Yu-Joung Choi, Boh-Ram Kim, Seung-Hoon Lee
Publikováno v:
Oncotarget
Colony stimulating factor 1 receptor (CSF-1R) regulates the monocyte/macrophage system, which is an essential component of cancer development. Therefore, CSF-1R might be an effective target for anti-cancer therapy. The overexpression of transforming
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e154f7970e010e3a2f753bff0b3887bb
https://doi.org/10.18632/oncotarget.20296
https://doi.org/10.18632/oncotarget.20296
Publikováno v:
Cellular Signalling. 27:2150-2159
In this study, we investigated a possible mechanism of β2-microglobulin (β2M) function in cancer metastases in vitro, using a human ovarian carcinoma cell line. β2M, a modulator acts as a cell growth-promoting and cellular signaling factors, was i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f6992f2c9ca91d628dae7648001db4
https://doi.org/10.1016/j.cellsig.2015.08.008
https://doi.org/10.1016/j.cellsig.2015.08.008
Autor:
Young Bok Ko, Yeonah Lee, Kyungsil Yoon, Seung Hee Seo, Min A Lee, Jung Bo Yang, Eun Kyung Choi, Mi Sun Park, Seung Bae Rho, Boh-Ram Kim
Publikováno v:
Cellular Signalling. 26:2562-2572
Wnt inhibitory factor-1 (WIF1) is a conserved lipid-binding protein that interrupts Wnt ligands by interacting with their Frizzled receptors. Thus, they may suppress the activation of the Wnt/β-catenin triggered signaling cascade. Recently, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44bcdd1be967f2af337c83e8b9a562b7
https://doi.org/10.1016/j.cellsig.2014.07.026
https://doi.org/10.1016/j.cellsig.2014.07.026
Publikováno v:
Genes & Cancer
Doxazosin, a commonly prescribed treatment for patients with benign prostatic hyperplasia, serves as an α1-blocker of the adrenergic receptors. In this study, we calculated its effect on the ovarian carcinoma cells. Doxazosin induces dose-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e240a522541f6e137fb061eb7ab2273
https://doi.org/10.18632/genesandcancer.37
https://doi.org/10.18632/genesandcancer.37
Autor:
Jeong Heon Lee, Seung Bae Rho, Seung Myung Dong, Sung Ho Park, Boh-Ram Kim, Seung-Hoon Lee, Sung Taek Park
Publikováno v:
Cellular Signalling. 26:1506-1513
Human γ-aminobutyrate type A (GABAA) receptor-binding protein (GABARBP), a tumor suppressor protein with apoptotic function, can be inhibited in response to angiogenesis through the PI3K/Akt signaling cascades. Here, we investigated whether GABARBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcd34b74259a530ebb7772a73051a3a
https://doi.org/10.1016/j.cellsig.2014.03.017
https://doi.org/10.1016/j.cellsig.2014.03.017