Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Bogusz Kulawiak"'
Autor:
Helmut Bischof, Selina Maier, Piotr Koprowski, Bogusz Kulawiak, Sandra Burgstaller, Joanna Jasińska, Kristian Serafimov, Monika Zochowska, Dominic Gross, Werner Schroth, Lucas Matt, David Arturo Juarez Lopez, Ying Zhang, Irina Bonzheim, Florian A Büttner, Falko Fend, Matthias Schwab, Andreas L Birkenfeld, Roland Malli, Michael Lämmerhofer, Piotr Bednarczyk, Adam Szewczyk, Robert Lukowski
Publikováno v:
eLife, Vol 12 (2024)
Alterations in the function of K+ channels such as the voltage- and Ca2+-activated K+ channel of large conductance (BKCa) reportedly promote breast cancer (BC) development and progression. Underlying molecular mechanisms remain, however, elusive. Her
Externí odkaz:
https://doaj.org/article/60f91b8d7664470fa1f56e117e4caef3
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The activation of mitochondrial large conductance calcium-activated potassium (mitoBKCa) channels increases cell survival during ischemia/reperfusion injury of cardiac cells. The basic biophysical and pharmacological properties of mitoBKCa c
Externí odkaz:
https://doaj.org/article/f49de50f2d0e446d8f6b5f2c3a700948
Autor:
Bogusz Kulawiak, Adam Szewczyk
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
In this paper, the current challenges of mitochondrial potassium channels research were critically reviewed. Even though recent progress in understanding K+ traffic in mitochondria has been substantial, some basic issues of this process remain unreso
Externí odkaz:
https://doaj.org/article/ae82e3eef20d4998b802d3ffc8572683
Publikováno v:
Membranes, Vol 13, Iss 3, p 360 (2023)
In the inner mitochondrial membrane, several potassium channels that play a role in cell life and death have been identified. One of these channels is the ATP-regulated potassium channel (mitoKATP). The ROMK2 potassium channel is a potential molecula
Externí odkaz:
https://doaj.org/article/215db25b4e8548b4a862c6825faef580
Publikováno v:
Molecules, Vol 27, Iss 1, p 299 (2022)
Mitochondrial potassium channels control potassium influx into the mitochondrial matrix and thus regulate mitochondrial membrane potential, volume, respiration, and synthesis of reactive oxygen species (ROS). It has been found that pharmacological ac
Externí odkaz:
https://doaj.org/article/d7ec0b631916445890e5deee8d7a778a
Publikováno v:
Cells, Vol 10, Iss 6, p 1554 (2021)
Mitochondria play a fundamental role in the energetics of cardiac cells. Moreover, mitochondria are involved in cardiac ischemia/reperfusion injury by opening the mitochondrial permeability transition pore which is the major cause of cell death. The
Externí odkaz:
https://doaj.org/article/347f8d767d4945c695a390c37194df3e
Publikováno v:
Molecules, Vol 26, Iss 11, p 3233 (2021)
Mitochondria play a key role in energy metabolism within the cell. Potassium channels such as ATP-sensitive, voltage-gated or large-conductance Ca2+-regulated channels have been described in the inner mitochondrial membrane. Several hypotheses have b
Externí odkaz:
https://doaj.org/article/78d3141a59004be58d8f34d7012ce304
Autor:
Michał Laskowski, Bartłomiej Augustynek, Piotr Bednarczyk, Monika Żochowska, Justyna Kalisz, Brian O’Rourke, Adam Szewczyk, Bogusz Kulawiak
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5323 (2019)
An increased flux of potassium ions into the mitochondrial matrix through the ATP-sensitive potassium channel (mitoKATP) has been shown to provide protection against ischemia-reperfusion injury. Recently, it was proposed that the mitochondrial-target
Externí odkaz:
https://doaj.org/article/b09fd8b3267846228fc7a5606d719b59
Autor:
Bartłomiej Augustynek, Piotr Koprowski, Daria Rotko, Wolfram S. Kunz, Adam Szewczyk, Bogusz Kulawiak
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 353 (2018)
Potassium channel openers (KCOs) have been shown to play a role in cytoprotection through the activation of mitochondrial potassium channels. Recently, in several reports, a number of data has been described as off-target actions for KCOs. In the pre
Externí odkaz:
https://doaj.org/article/bdb30b56614b41b196e0cb4696ad06e0
Autor:
Adam Szewczyk, Alexei P. Kudin, Wolfram S. Kunz, Krzysztof Dołowy, Grzegorz Wilczynski, Marta Piwońska, Bogusz Kulawiak, Jolanta Skalska, Piotr Bednarczyk
Publikováno v:
International Journal of Molecular Sciences, Vol 10, Iss 3, Pp 1104-1120 (2009)
The mitochondrial response to changes of cytosolic calcium concentration has a strong impact on neuronal cell metabolism and viability. We observed that Ca2+ additions to isolated rat brain mitochondria induced in potassium ion containing media a mit
Externí odkaz:
https://doaj.org/article/f6ef90ad3a5c4c30805194972eff007e