Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Boguslaw Stec"'
Autor:
Boguslaw Stec
Publikováno v:
Biophysica, Vol 3, Iss 2, Pp 288-306 (2023)
Covalent addition of the threonylcarbamoyl group to N(6) of adenosine 37 (t6A modification) within the anticodon loop of several tRNAs is central to the translational fidelity in all known organisms. Structures for each of the enzyme components in th
Externí odkaz:
https://doaj.org/article/2666efcbc70f40ea82f1ee630c714cb2
Autor:
Adeba Mohammad, Adriana Bon Ramos, Bobby W. K. Lee, Spencer W. Cohen, Maryam K. Kiani, Dirk Iwata-Reuyl, Boguslaw Stec, Manal A. Swairjo
Publikováno v:
Biomolecules, Vol 7, Iss 1, p 30 (2017)
QueF enzymes catalyze the nicotinamide adenine dinucleotide phosphate (NADPH)-dependent reduction of the nitrile group of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in the biosynthetic pathway to the tRNA modified nucleosi
Externí odkaz:
https://doaj.org/article/7499677c37d347a3a4ca21b1160dcac0
Autor:
Katarzyna Gawlik, Sergey A Shiryaev, Wenhong Zhu, Khatereh Motamedchaboki, Roxane Desjardins, Robert Day, Albert G Remacle, Boguslaw Stec, Alex Y Strongin
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5031 (2009)
Before furin can act on protein substrates, it must go through an ordered process of activation. Similar to many other proteinases, furin is synthesized as a zymogen (profurin) which becomes active only after the autocatalytic removal of its auto-inh
Externí odkaz:
https://doaj.org/article/d2db3482d0ba40c39fe0eefd5a615202
Autor:
Dominik L. Stec, Boguslaw Stec
Publikováno v:
The Protein Journal. 41:55-70
To shed light onto the activation mechanism of vinculin, we carried out a detailed refinement of chicken vinculin and compared it to the human protein which is greater than 95% identical. Refinement resulted in a complete and significantly improved m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b42dd3c541f1e0754791c22c6e7db9c
https://doi.org/10.1007/s10930-022-10040-1
https://doi.org/10.1007/s10930-022-10040-1
Autor:
Yaqiong Lin, William C. Hwang, Boguslaw Stec, Eugenio Santelli, Michael Farzan, Wayne A. Marasco, Robert C. Liddington, Jianhua Sui, Lukasz Jaroszewski
Publikováno v:
The Journal of Biological Chemistry
Journal of Biological Chemistry
Journal of Biological Chemistry
Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease that caused pandemic spread in 2003. The etiological agent of SARS is a novel coronavirus (SARS-CoV). The coronaviral surface spike protein S is a type I transmembrane gly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59de7e6eb4a5beb8902a7af79f1ed5ba
http://europepmc.org/articles/PMC7981188
http://europepmc.org/articles/PMC7981188
Autor:
Deepthi L Anipindi, Heidi Erlandsen, James L. Cole, Brian J. Maniaci, Tom Huxford, John J. Love, Colin H. Lipper, Boguslaw Stec
Publikováno v:
Biochemistry. 58:2199-2207
The ability to precisely control protein complex formation has high utility in the expanding field of biomaterials. Driving protein-protein binding through metal-ligand bridging interactions is a promising method of achieving this goal. Furthermore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f2ad6091f262c143e9f9849454ffe7
https://doi.org/10.1021/acs.biochem.9b00055
https://doi.org/10.1021/acs.biochem.9b00055
Autor:
Susan Bayooz, Manal A. Swairjo, Boguslaw Stec, William Swinehart, Jamie M. Schiffer, Naduni Paranagama, Dirk Iwata-Reuyl, Vanessa Quach, Amit Luthra, Phuc Phan
Publikováno v:
Nucleic Acids Research
The universally conserved N6-threonylcarbamoyladenosine (t6A) modification of tRNA is essential for translational fidelity. In bacteria, t6A biosynthesis starts with the TsaC/TsaC2-catalyzed synthesis of the intermediate threonylcarbamoyl adenylate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5318fff0026b67d60a5fb3258533c7
https://pubmed.ncbi.nlm.nih.gov/31114923
https://pubmed.ncbi.nlm.nih.gov/31114923
Autor:
Susan Bayooz, Phuc Phan, Amit Luthra, William Swinehart, Dirk Iwata-Reuyl, Boguslaw Stec, Manal A. Swairjo
Publikováno v:
Nucleic Acids Research
The universal N(6)-threonylcarbamoyladenosine (t6A) modification at position 37 of ANN-decoding tRNAs is central to translational fidelity. In bacteria, t6A biosynthesis is catalyzed by the proteins TsaB, TsaC/TsaC2, TsaD and TsaE. Despite intense re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2535d9ad366142ce4329e3a36cccf864
https://doi.org/10.1096/fasebj.2018.32.1_supplement.790.1
https://doi.org/10.1096/fasebj.2018.32.1_supplement.790.1
Autor:
Boguslaw Stec, Jonathan Alvarez, Byron W. Purse, Andrew Gustafson, Manal A. Swairjo, Naduni Paranagama, Dirk Iwata-Reuyl, George N. Samaan, Shilah A. Bonnett, Amit Luthra
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a424c566e47acbbafea4053ac2492edf
https://doi.org/10.1096/fasebj.2018.32.1_supplement.810.1
https://doi.org/10.1096/fasebj.2018.32.1_supplement.810.1
Publikováno v:
Journal of Biological Chemistry. 290:1592-1606
The lipid phosphatase activity of the tumor suppressor phosphatase and tensin homolog (PTEN) is enhanced by the presence of its biological product, phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). This enhancement is suggested to occur via the prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cdc56b89a9d7f421e0930da92f02ac6
https://doi.org/10.1074/jbc.m114.588590
https://doi.org/10.1074/jbc.m114.588590