Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bogumila Konieczny"'
Autor:
Alice Kamphorst, Masashi Watanabe, Koichi Araki, Mohammed Ata Ur Rasheed, Carl Davis, Shu Yang, Bogumila Konieczny, Richard Hodes, Rafi Ahmed
Publikováno v:
The Journal of Immunology. 194:201.7-201.7
Upon activation CD4 T cells differentiate into different subsets that have distinct functions in the immune response. Antigen presentation in the presence of co-stimulation and cytokines is required for optimal CD4 T cell activation and differentiati
Publikováno v:
The Journal of Immunology. 192:65.9-65.9
CD8 T cells play an essential role in controlling viral as well as intracellular bacterial and parasitic infections. Memory CD8 T cells provide protective immunity upon re-encounter with the same pathogens. A better understanding of memory CD8 T cell
Autor:
Benjamin Youngblood, Jeffery Hale, Xiaojin Xu, Eunseon Ahn, Koichi Araki, Erin West, Bogumila Konieczny, Rafi Ahmed
Publikováno v:
The Journal of Immunology. 190:117.13-117.13
Memory CD8 T cells generated from acute infection or vaccination have the potential to provide the host with life-long immunity against re-infection, yet one of the least understood and most remarkable attributes of memory T cells is their ability to
Autor:
Pablo Penaloza MacMaster, Vaiva Vezys, Sang-Jun Ha, Bogumila Konieczny, Daniel Barber, Robert Mittler, Rafi Ahmed
Publikováno v:
The Journal of Immunology. 182:90.22-90.22
The PDL-1:PD-1 pathway is involved in T cell exhaustion after chronic viral infection. PD-1 can bind to either PDL-1 or PDL-2, whereas PDL-1 can bind to either PD-1 or B7.1. We tested the effect of combining standard aPDL-1 blockade with a4-1BB (3H3