A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery

Autor: Kim, MO, Feng, X, Feixas, F, Zhu, W, Lindert, S, Bogue, S, Sinko, W, De Oliveira, C, Rao, G, Oldfield, E, McCammon, JA

Publikováno v: Chemical biology & drug design, vol 85, iss 6
Kim, MO; Feng, X; Feixas, F; Zhu, W; Lindert, S; Bogue, S; et al.(2015). A molecular dynamics investigation of Mycobacterium tuberculosis prenyl synthases: Conformational flexibility and implications for computer-aided drug discovery. Chemical Biology and Drug Design, 85(6), 756-769. doi: 10.1111/cbdd.12463. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/3dd8c8mr

© 2014 John Wiley & Sons A/S. With the rise in antibiotic resistance, there is interest in discovering new drugs active against new targets. Here, we investigate the dynamic structures of three isoprenoid synthases from Mycobacterium tuberculosis us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4b04e266cdd3240b80b1de098c66ca64
https://escholarship.org/uc/item/3dd8c8mr

Geochemistry of Kauai shield-stage lavas: Implications for the chemical evolution of the Hawaiian plume

Autor: Mukhopadhyay, S., Lassiter, J. C., Farley, K. A., Bogue, S. W.

We measured He, Sr, Nd, Pb, and Os isotope ratios and major and trace element concentrations in stratigraphically and paleomagnetically controlled shield-stage lavas from Kauai, Hawaii. The range of 3He/4He ratios (17–28 RA) from Kauai is similar t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od________38::7bb5383497f2e3e306d0eeb040621dbd
https://resolver.caltech.edu/CaltechAUTHORS:MUKggg03

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.