Zobrazeno 1 - 10 of 486 pro vyhledávání: '"Bogosian A"'
1
Akademický článek
De novo generation of multi-target compounds using deep generative chemistry
Autor: Brenton P. Munson, Michael Chen, Audrey Bogosian, Jason F. Kreisberg, Katherine Licon, Ruben Abagyan, Brent M. Kuenzi, Trey Ideker
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Polypharmacology drugs—compounds that inhibit multiple proteins—have many applications but are difficult to design. To address this challenge we have developed POLYGON, an approach to polypharmacology based on generative reinforcement le
Externí odkaz: https://doaj.org/article/55b169129e9145c5abf476bbec8ac7f5
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2
Akademický článek
Gaining consensus on emotional wellbeing themes and preferences for digital intervention type and content to support the mental health of young people with long‐term health conditions: A Delphi study
Autor: Jennie Brown, Lauren Cox, Kathleen Mulligan, Stephanie Wilson, Michelle Heys, Polly Livermore, Suzy Gray, Angeliki Bogosian
Publikováno v: Health Expectations, Vol 27, Iss 2, Pp n/a-n/a (2024)
Abstract Background Young people (YP) with long‐term conditions (LTCs) are at greater risk of psychological distress than those without LTCs. Despite this, there is a scarcity of quality digital interventions designed to help improve mental wellbei
Externí odkaz: https://doaj.org/article/655ac23ce9334131a6dc260deb4b672c
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4
Akademický článek
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6
Akademický článek
Key demographics and psychological skills associated with adjustment to progressive Multiple Sclerosis early in the diagnosis
Autor: Angeliki Bogosian, Fern Day, Sam Norton, Eli Silber, Mohamed Sakel, Basil Sharrack, Rona Moss-Morris
Publikováno v: Frontiers in Rehabilitation Sciences, Vol 3 (2022)
Background/purposeBeing diagnosed with a progressive type of multiple sclerosis (MS) has been associated with worse psychological outcomes compared to relapsing-remitting type. Previous studies of adjustment to MS have primarily focused on relapsing-
Externí odkaz: https://doaj.org/article/f4b217265316428084feb1e98a1c04c6
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8
Akademický článek
Prioritising target non-pharmacological interventions for research in Parkinson’s disease: achieving consensus from key stakeholders
Autor: Angeliki Bogosian, Lorna Rixon, Catherine S. Hurt
Publikováno v: Research Involvement and Engagement, Vol 6, Iss 1, Pp 1-9 (2020)
Abstract Background In 2014 Parkinson’s UK conducted a research prioritisation exercise with stakeholders highlighting important clinical research questions. The exercise highlighted the need for effective interventions to be developed and tested t
Externí odkaz: https://doaj.org/article/e6377335a2be492bbd4c30729bfc42eb
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9
Akademický článek
The experiences of people who quit khat and the health care professionals who support them
Autor: Suhana Begum, Angeliki Bogosian, Hayley McBain
Publikováno v: Addiction and Health, Vol 11, Iss 4, Pp 243-255 (2019)
Background: This study aimed to explore the barriers and enablers to quitting khat from the perspective ofusers and the barriers and enablers to supporting users to quit from the perspective of healthcareprofessionals (HCPs).Methods: The present qual
Externí odkaz: https://doaj.org/article/454ac33743214ca38ecaa4264e7430c0
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