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The extent of B-cell activation and dysfunction preceding lymphoma development in HIV-positive people

Autor: Shepherd, L., Borges, Á. H., Harvey, R., Bower, M., Grulich, A., Silverberg, M., Weber, J., Ristola, M., Viard, J. -P., Bogner, J. R., Gargalianos-Kakolyris, P., Mussini, C., Mansinho, K., Yust, I., Paduta, D., Jilich, D., Smiatacz, T., Radoi, R., Tomazic, J., Plomgaard, P., Frikke-Schmidt, R., Lundgren, J., Mocroft, A., Losso, M., Kundro, M., Schmied, B., Karpov, I., Vassilenko, A., Mitsura, V. M., Paduto, D., Clumeck, N., De Wit, S., Delforge, M., Florence, E., Vandekerckhove, L., Hadziosmanovic, V., Begovac, J., Machala, L., Sedlacek, D., Kronborg, G., Benfield, T., Gerstoft, J., Katzenstein, T., Møller, N. F., Pedersen, C., Ostergaard, L., Wiese, L., Nielsen, L. N., Zilmer, K., Jelena, S., Nakkusosakond, S., Kohtla-Järve, Null, Aho, I., Girard, P. -M., Pradier, C., Fontas, E., Duvivier, C., Rockstroh, J., Schmidt, R., Degen, O., Stellbrink, H. J., Stefan, C., Fätkenheuer, G., Chkhartishvili, N., Gargalianos, P., Xylomenos, G., Armenis, K., Sambatakou, H., Szlávik, J., Gottfredsson, M., Mulcahy, F., Turner, D., Burke, M., Shahar, E., Hassoun, G., Elinav, H., Haouzi, M., Elbirt, D., Sthoeger, Z. M., D'Arminio Monforte, A., Esposito, R., Mazeu, I., Mazzotta, F., Gabbuti, A., Vullo, V., Lichtner, M., Zaccarelli, M., Antinori, A., Acinapura, R., Plazzi, M., Lazzarin, A., Castagna, A., Gianotti, N., Galli, M., Ridolfo, A., Sacco, Osp. L, Rozentale, B., Uzdaviniene, V., Matulionyte, R., Staub, T., Hemmer, R., Reiss, P., Ormaasen, V., Maeland, A., Bruun, J., Knysz, B., Gasiorowski, J., Inglot, M., Horban, A., Bakowska, E., Flisiak, R., Grzeszczuk, A., Parczewski, M., Maciejewska, K., Aksak-Was, B., Beniowski, M., Mularska, E., Gensing, M., Jablonowska, E., Malolepsza, E., Wojcik, K., Mozer-Lisewska, I., Caldeira, L., Maltez, F., Oprea, C., Victor, B., Panteleev, A., Panteleev, O., Yakovlev, A., Trofimora, T., Khromova, I., Kuzovatova, E., Borodulina, E., Vdoushkina, E., Jevtovic, D., Gatell, J. M., Miró, J. M., Moreno, S., Rodriguez, J. M., Clotet, B., Jou, A., Paredes, R., Tural, C., Puig, J., Bravo, I., Domingo, P., Gutierrez, M., Mateo, G., Sambeat, M. A., Laporte, J. M., Falconer, K., Thalme, A., Sonnerborg, A., Blaxhult, A., Flamholc, L., Scherrer, A., Weber, R., Cavassini, M., Calmy, A., Furrer, H., Battegay, M., Schmid, P., Kuznetsova, A., Kyselyova, G., Sluzhynska, M., Gazzard, B., Johnson, A. M., Simons, E., Edwards, S., Phillips, A., Johnson, M. A., Orkin, C., Scullard, G., Clarke, A., Leen, C., Gatell, J., d'Arminio Monforte, A., Kirk, O., Peters, L., Matthews, C., Fischer, A. H., Bojesen, A., Raben, D., Kristensen, D., Grønborg Laut, K., Larsen, J. F., Podlekareva, D., Cozzi-Lepri, A., Schultze, A., Amele, S.

Publikováno v: Shepherd, L, Borges, Á H, Harvey, R, Bower, M, Grulich, A, Silverberg, M, Weber, J, Ristola, M, Viard, J-P, Bogner, J R, Gargalianos-Kakolyris, P, Mussini, C, Mansinho, K, Yust, I, Paduta, D, Jilich, D, Smiatacz, T, Radoi, R, Tomazic, J, Plomgaard, P, Frikke-Schmidt, R, Lundgren, J, Mocroft, A & EuroSIDA in EuroCOORD 2018, ' The extent of B-cell activation and dysfunction preceding lymphoma development in HIV-positive people ', HIV Medicine, vol. 19, no. 2, pp. 90-101 . https://doi.org/10.1111/hiv.12546
HIV medicine, 19(2), 90-101. Wiley-Blackwell

OBJECTIVES: B-cell dysfunction and activation are thought to contribute to lymphoma development in HIV-positive people; however, the mechanisms are not well understood. We investigated levels of several markers of B-cell dysfunction [free light chain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68ab742f7ce98e102d3af154a89d511
http://www.wiley.com/bw/journal.asp?ref=1464-2662

Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study

Autor: Rodger, A. J., Cambiano, V., Phillips, A. N., Bruun, T., Raben, D., Lundgren, J., Vernazza, P., Collins, S., Degen, O., Corbelli, G. M., Estrada, V., Geretti, A. M., Beloukas, A., Coll, P., Antinori, A., Nwokolo, N., Rieger, A., Prins, J. M., Blaxhult, A., Weber, R., Van Eeden, A., Brockmeyer, N. H., Clarke, A., del Romero Guerrero, J., Raffi, F., Bogner, J. R., Wandeler, G., Gerstoft, J., Gutierrez, F., Brinkman, K., Kitchen, M., Ostergaard, L., Leon, A., Ristola, M., Jessen, H., Stellbrink, H. -J., Cobarsi, P., Nieto, A., Meulbroek, M., Carrillo, A., Saz, J., Guerrero, J. D. R., Garcia, M. V., Masia, M., Robledano, C., Leal, L., Redondo, E. G., Estrada, V. P., Marquez, R., Sandoval, R., Viciana, P., Espinosa, N., Lopez-Cortes, L., Podzamczer, D., Tiraboschi, J., Morenilla, S., Antela, A., Losada, E., Sewell, J., Kirk, S., Knott, A., Fernandez, T., Gompels, M., Jennings, L., Ward, L., Fox, J., Lwanga, J., Lee, M., Gilson, R., Leen, C., Morris, S., Clutterbuck, D., Brady, M., Asboe, D., Fedele, S., Fidler, S., Brockmeyer, N., Potthoff, A., Skaletz-Rorowski, A., Bogner, J., Seybold, U., Roider, J., Jessen, A., Ruzicic, S., Kummerle, T., Lehmann, C., Bartel, S., Hufner, A., Rockstroh, J., Mohrmann, K., Boesecke, C., Krznaric, I., Ingiliz, P., Grube, C., Braun, D., Gunthard, H., Furrer, H., Rauch, A., Schmid, P., Rasi, M., Borso, D., Stratmann, M., Caviezel, O., Stoeckle, M., Battegay, M., Tarr, P., Christinet, V., Jouinot, F., Isambert, C., Bernasconi, E., Bernasconi, B., Jensen, L. P., Bayer, A. A., Yehdego, Y., Bach, A., Handberg, P., Kronborg, G., Pedersen, S. S., Bulow, N., Ramskover, B., Debnam, O., Sutinen, J., Ask, R., Hildingsson-Lundh, B., Westling, K., Frisen, E. -M., Cortney, G., O'Dea, S., De Wit, S., Necsoi, C., Vandekerckhove, L., Goffard, J. -C., Henrard, S., Prins, J., Nobel, H. -H., Weijsenfeld, A., Elsenburg, L., Vos, D., Hoijenga, I., Gisolf, E., Van Bentum, P., Verhagen, D., Billaud, E., Ohayon, M., Gosset, D., Fior, A., Pialoux, G., Thibaut, P., Chas, J., Leclercq, V., Pechenot, V., Coquelin, V., Pradier, C., Breaud, S., Touzeau-Romer, V., Kitchen - Maria Geit, M., Sarcletti, M., Gisinger, M., Oellinger, A., Menichetti, S., Bini, T., Mussini, C., Meschiari, M., Di Biagio, A., Taramasso, L., Celesia, B. M., Gussio, M., Janeiro, N.

Publikováno v: LANCET
r-FISABIO. Repositorio Institucional de Producción Científica
instname
Rodger, A J, Cambiano, V, Phillips, A N, Bruun, T, Raben, D, Lundgren, J, Vernazza, P, Collins, S, Degen, O, Corbelli, G M, Estrada, V, Geretti, A M, Beloukas, A, Beloukas, A, Coll, P, Antinori, A, Nwokolo, N, Rieger, A, Prins, J M, Blaxhult, A, Weber, R, Van Eeden, A, Brockmeyer, N H, Clarke, A, del Romero Guerrero, J, Raffi, F, Bogner, J R, Wandeler, G, Gerstoft, J, Gutiérrez, F, Brinkman, K, Kitchen, M, Ostergaard, L, Leon, A, Ristola, M, Jessen, H, Stellbrink, H J, Phillips, A N, Lundgren, J & PARTNER Study Group 2019, ' Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER) : final results of a multicentre, prospective, observational study ', The Lancet, vol. 393, no. 10189, pp. 2428-2438 . https://doi.org/10.1016/S0140-6736(19)30418-0
Rodger, A J, Cambiano, V, Bruun, T, Vernazza, P, Collins, S, Degen, O, Corbelli, G M, Estrada, V, Geretti, A M, Beloukas, A, Raben, D, Coll, P, Antinori, A, Nwokolo, N, Rieger, A, Prins, J M, Blaxhult, A, Weber, R, Van Eeden, A, Brockmeyer, N H, Clarke, A, Del Romero Guerrero, J, Raffi, F, Bogner, J R, Wandeler, G, Gerstoft, J, Gutiérrez, F, Brinkman, K, Kitchen, M, Ostergaard, L, Leon, A, Ristola, M, Jessen, H, Stellbrink, H-J, Phillips, A N, Lundgren, J & Group, PARTNER S 2019, ' Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. ', The Lancet, vol. 393, no. 10189 . https://doi.org/10.1016/S0140-6736(19)30418-0
Lancet, 393(10189), 2428-2438. Elsevier Limited
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Lancet (London, England)
PARTNER Study Group 2019, ' Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER) : final results of a multicentre, prospective, observational study ', Lancet Oncology, vol. 393, no. 10189, pp. 2428-2438 . https://doi.org/10.1016/S0140-6736(19)30418-0
Rodger, Alison J; Cambiano, Valentina; Bruun, Tina; Vernazza, Pietro; Collins, Simon; Degen, Olaf; Corbelli, Giulio Maria; Estrada, Vicente; Geretti, Anna Maria; Beloukas, Apostolos; Raben, Dorthe; Coll, Pep; Antinori, Andrea; Nwokolo, Nneka; Rieger, Armin; Prins, Jan M; Blaxhult, Anders; Weber, Rainer; Van Eeden, Arne; Brockmeyer, Norbert H; ... (2019). Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet, 393(10189), pp. 2428-2438. Elsevier 10.1016/S0140-6736(19)30418-0

BACKGROUND: The level of evidence for HIV transmission risk through condomless sex in serodifferent gay couples with the HIV-positive partner taking virally suppressive antiretroviral therapy (ART) is limited compared with the evidence available for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea8f4f26ea11549f0348c459e851aa8
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4610