Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.

Autor: Gut F; Gene Center, Ludwig-Maximilians-Universität, 81377 Munich, Germany; Department of Biochemistry, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Käshammer L; Gene Center, Ludwig-Maximilians-Universität, 81377 Munich, Germany; Department of Biochemistry, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Lammens K; Gene Center, Ludwig-Maximilians-Universität, 81377 Munich, Germany; Department of Biochemistry, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Bartho JD; Gene Center, Ludwig-Maximilians-Universität, 81377 Munich, Germany; Department of Biochemistry, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Boggusch AM; Gene Center, Ludwig-Maximilians-Universität, 81377 Munich, Germany; Department of Biochemistry, Ludwig-Maximilians-Universität, 81377 Munich, Germany., van de Logt E; Gene Center, Ludwig-Maximilians-Universität, 81377 Munich, Germany; Department of Biochemistry, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Kessler B; Gene Center, Ludwig-Maximilians-Universität, 81377 Munich, Germany; Department of Biochemistry, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Hopfner KP; Gene Center, Ludwig-Maximilians-Universität, 81377 Munich, Germany; Department of Biochemistry, Ludwig-Maximilians-Universität, 81377 Munich, Germany. Electronic address: hopfner@genzentrum.lmu.de.

Publikováno v: Molecular cell [Mol Cell] 2022 Sep 15; Vol. 82 (18), pp. 3513-3522.e6. Date of Electronic Publication: 2022 Aug 19.