Výsledky vyhledávání - "Bogen Bjarne"

Akademický článek

Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model

Autor: Blomhoff Rune, Sundan Anders, Naderi Soheil, Hauglin Harald, Hofgaard Peter O, Follin-Arbelet Virginie, Bogen Bjarne, Blomhoff Heidi K

Publikováno v: BMC Cancer, Vol 11, Iss 1, p 301 (2011)

Abstract Background Multiple myeloma is an incurable disease requiring the development of effective therapies which can be used clinically. We have elucidated the potential for manipulating the cAMP signaling pathway as a target for inhibiting the gr

Externí odkaz: https://doaj.org/article/33ed73f49ab8499fa25dc75a04da4fa5

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Akademický článek

Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins

Autor: Lunde Elin, Løset Geir, Bogen Bjarne, Sandlie Inger

Publikováno v: BMC Biotechnology, Vol 10, Iss 1, p 61 (2010)

Abstract Background Whereas T cell receptors (TCRs) detect peptide/major histocompatibility complexes (pMHCs) with exquisite specificity, there are challenges regarding their expression and use as soluble detection molecules due to molecular instabil

Externí odkaz: https://doaj.org/article/30486c5616994625a37d27d9a9074c10

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Akademický článek

Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA

Autor: Bogen Bjarne, Kristiansen Per E, Lunde Elin, Gunnarsen Kristin S, Sandlie Inger, Løset Geir Å

Publikováno v: BMC Biotechnology, Vol 10, Iss 1, p 8 (2010)

Abstract Background Efficient expression systems exist for antibody (Ab) molecules, which allow for characterization of large numbers of individual Ab variants. In contrast, such expression systems have been lacking for soluble T cell receptors (TCRs

Externí odkaz: https://doaj.org/article/04b0439ead6a433f99ef42d5281fff4f

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