Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Bogdan Olenyuk"'
Autor:
Anil H Kadam, Kathirvel Kandasamy, Tim Buss, Brittany Cederstrom, Chun Yang, Sreekanth Narayanapillai, Juan Rodriguez, Michael D Levin, Jim Koziol, Bogdan Olenyuk, Zea Borok, Adrian Chrastina, Jan E Schnitzer
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276462 (2022)
The long-sought-after "magic bullet" in systemic therapy remains unrealized for disease targets existing inside most tissues, theoretically because vascular endothelium impedes passive tissue entry and full target engagement. We engineered the first
Externí odkaz:
https://doaj.org/article/2607132e15414d62be5dca6011dd8966
Publikováno v:
Inorganics, Vol 11, Iss 2, p 54 (2023)
Metallacycles and metallacages constitute a class of coordination compounds composed of metal ions and organic ligands. Because of their precise stoichiometry, the flexibility and viability of design, metallacycles and metallacages have attracted con
Externí odkaz:
https://doaj.org/article/d1993797436940f9a9ac77fd909e9abe
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 7, Pp o1583-o1584 (2009)
The title compound, C28H34N2O8S2, was synthesized as part of a project to develop synthetic routes to analogues of sporidesmins, a class of secondary metabolite produced by the filamentous fungi Chaetomium and Pithomyces sp. The complete molecule is
Externí odkaz:
https://doaj.org/article/d483f87398f04f9d9f2043e3e06f360f
Autor:
Chonglu Li, Le Tu, Jingfang Yang, Chang Liu, Yuling Xu, Junrong Li, Wei Tuo, Bogdan Olenyuk, Yan Sun, Peter J. Stang, Yao Sun
Publikováno v:
Chemical Science. 14:2901-2909
Acceptor engineered supramolecular photosensitizers with a proming phototoxicity index (PI) for effective and safe photodynamic therapy in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9eb136349d76b025b9a2050a21e0948
https://doi.org/10.1039/d2sc06936a
https://doi.org/10.1039/d2sc06936a
Autor:
Anil H. Kadam, Kathirvel Kandasamy, Tim Buss, Brittany Cederstrom, Chun Yang, Sreekanth Narayanapillai, Juan Rodriguez, Michael D. Levin, Jim Koziol, Bogdan Olenyuk, Zea Borok, Adrian Chrastina, Jan E. Schnitzer
The long-sought-after “magic bullet” in systemic therapy remains unrealized for disease targets existing inside most tissues, theoretically because vascular endothelium impedes passive tissue entry and full target engagement. We engineered the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3614cc01ecfadbd9947b87ef1d69a8f4
https://doi.org/10.1101/2022.09.12.507679
https://doi.org/10.1101/2022.09.12.507679
Autor:
Amanda Silberstein, Lina He, Bogdan Olenyuk, Joseph W. Stiles, Tiezheng Jia, Thomas F. Martinez, Alissa A. Hare, Yang Li, Bangyan L. Stiles, Peter B. Dervan, John Gallagher, Chien-Yu Chen
Publikováno v:
Med Chem Res
Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, vol 29, iss 4
Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, vol 29, iss 4
The orphan nuclear receptors estrogen-related receptors (ERRs) bind to the estrogen-related receptor response element (ERRE) to regulate transcriptional programs in cellular metabolism and cancer cell growth. In this study, we evaluated the potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4ef2e105e0b11764d04977cd0da9e9
https://resolver.caltech.edu/CaltechAUTHORS:20200226-143501183
https://resolver.caltech.edu/CaltechAUTHORS:20200226-143501183
Autor:
Thomas C. Chen, Rajesh Kota, Jean C. Shih, Susan Groshen, Vijaya Pooja Vaikari, Swati Kushal, Tzu-Shao Yeh, Weijun Wang, Florence M. Hofman, Bogdan Olenyuk, Niyati Jhaveri, Kevin Chen
Publikováno v:
Oncotarget
// Swati Kushal 1, 5, * , Weijun Wang 2, 5, * , Vijaya Pooja Vaikari 1, 5 , Rajesh Kota 1, 5 , Kevin Chen 1, 5 , Tzu-Shao Yeh 1, 5, 6 , Niyati Jhaveri 3 , Susan L. Groshen 7 , Bogdan Z. Olenyuk 1 , Thomas C. Chen 2, 5 , Florence M. Hofman 2, 3, 5 , J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3596461937ee1b414889010bc5510be3
https://doi.org/10.18632/oncotarget.7283
https://doi.org/10.18632/oncotarget.7283
Autor:
Swati Kushal, Peter J. Stang, J. Bryant Pollock, Ivan Grishagin, Timothy R. Cook, Bogdan Olenyuk
Publikováno v:
Proceedings of the National Academy of Sciences. 111:18448-18453
The development of novel antitumor agents that have high efficacy in suppressing tumor growth, have low toxicity to nontumor tissues, and exhibit rapid localization in the targeted tumor sites is an ongoing avenue of research at the interface of chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64baee3789524202cfa8700c863c5761
https://doi.org/10.1073/pnas.1418712111
https://doi.org/10.1073/pnas.1418712111
Autor:
Thomas F. Brewer, Hanah Mesallati, Paramjit S. Arora, Brooke Bullock Lao, Ivan Grishagin, Bogdan Olenyuk
Publikováno v:
Proceedings of the National Academy of Sciences. 111:7531-7536
Development of small-molecule inhibitors of protein-protein interactions is a fundamental challenge at the interface of chemistry and cancer biology. Successful methods for design of protein-protein interaction inhibitors include computational and ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15333828fdfd1cd1424647d577c3572d
https://doi.org/10.1073/pnas.1402393111
https://doi.org/10.1073/pnas.1402393111
Publikováno v:
Journal of Medicinal Chemistry. 56:9170-9179
Nitrogen mustards, widely used as chemotherapeutics, have limited safety and efficacy. Mitochondria lack a functional nucleotide excision repair mechanism to repair DNA adducts and are sensitive to alkylating agents. Importantly, cancer cells have hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91c28f04273d26a0516e83aa6ca4c16
https://doi.org/10.1021/jm4012438
https://doi.org/10.1021/jm4012438