Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Bogdan Beirowski"'
Autor:
Gustavo Della-Flora Nunes, Emma R. Wilson, Leandro N. Marziali, Edward Hurley, Nicholas Silvestri, Bin He, Bert W. O’Malley, Bogdan Beirowski, Yannick Poitelon, Lawrence Wrabetz, M. Laura Feltri
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Prohibitin 2 can localize to the axon-Schwann-cell interface and is required for myelin formation. Here, the authors show that deletion of prohibitin 1 in Schwann cells instead triggers severe myelin loss likely caused by mitochondrial dysfunction, a
Externí odkaz:
https://doaj.org/article/dee61ba939654c5b97e3ebabed37e14e
Autor:
Elisabetta Babetto, Bogdan Beirowski
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 304-306 (2022)
Externí odkaz:
https://doaj.org/article/71c87729d742428aa785eebf5241680f
Autor:
Bogdan Beirowski
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105751- (2022)
Impaired bioenergetic capacity of the nervous system is thought to contribute to the pathogenesis of many neurodegenerative diseases (NDD). Since neuronal synapses are believed to be the major energy consumers in the nervous system, synaptic derangem
Externí odkaz:
https://doaj.org/article/fc726a3c69504ac5989bea281be6c56b
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 4, Pp 518-524 (2017)
Axonal degeneration is a pivotal feature of many neurodegenerative conditions and substantially accounts for neurological morbidity. A widely used experimental model to study the mechanisms of axonal degeneration is Wallerian degeneration (WD), which
Externí odkaz:
https://doaj.org/article/277a509096434c16b5c7c511c3e15ebd
Autor:
Keit Men Wong, Bogdan Beirowski
Publikováno v:
Communicative & Integrative Biology, Vol 11, Iss 1 (2018)
During nerve development, Schwann cells (SCs) build multilayered myelin sheaths around axons to accelerate nerve conduction. The mechanistic target of rapamycin complex 1 (mTORC1) downstream of PI3K/AKT signaling lately emerged as a central anabolic
Externí odkaz:
https://doaj.org/article/6763dcfda0df47f682d5baaed4463c61
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1422-1429 (2013)
Axon degeneration is an evolutionarily conserved process that drives the loss of damaged axons and is an early event in many neurological disorders, so it is important to identify the molecular constituents of this poorly understood mechanism. Here,
Externí odkaz:
https://doaj.org/article/e3987ee768544cf6aac60097d202f42d
Autor:
Stephanie A. Eid, Amy E. Rumora, Bogdan Beirowski, David L. Bennett, Junguk Hur, Masha G. Savelieff, Eva L. Feldman
Publikováno v:
Neuron.
Autor:
Fabrizio Passalacqua, Kyle Leatt, Nikita Chawla, Ruth-Ann Saddler, Elisabetta Babetto, Bogdan Beirowski
Publikováno v:
Frontiers for Young Minds. 10
Axons are the thin and long extensions of neuronal cells that snake away from the cell body. Axons in our nervous system are like bridges spanning long distances to bring information from one nerve cell to another. However, axons are alive and need n
Publikováno v:
Nature Neuroscience. 24:150-153