Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bogdan A. Solaja"'
Publikováno v:
Journal of the Serbian Chemical Society, Vol 73, Iss 11, Pp 1021-1025 (2008)
Several tetraoxane and 4-aminoquinoline molecules were prepared in order to examine the influence of ribofuranose as a carrier molecule on the antimalarial activity of test compounds. The synthesized compounds showed pronounced antimalarial activity
Externí odkaz:
https://doaj.org/article/ec31329b42b349c1b13027ba87979f70
Publikováno v:
ARKIVOC, Vol 2007, Iss 8, Pp 124-135 (2006)
Externí odkaz:
https://doaj.org/article/de690dbb600045b58b25f8b988fe806c
Publikováno v:
Journal of the Serbian Chemical Society, Vol 70, Iss 3, Pp 329-345 (2005)
A three-dimensional QSAR pharmacophore model for antimalarial activity of steroidal 1,2,4,5-tetraoxanes was developed from a set of 17 substituted antimalarial derivatives out of 27 analogues that exhibited remarkable in vitro activity (below 100 ng/
Externí odkaz:
https://doaj.org/article/0bf17d6508a44fd1b8df5cd1ed8e967a
Publikováno v:
Journal of the Serbian Chemical Society, Vol 69, Iss 10, Pp 769-775 (2004)
Synthesis of a steroidal dendrimer core possessing various functional termini, such as ester, carboxy and hydroxy, is presented. The approach described enables further simple manipulations for the introduction of more complex functionalities.
Externí odkaz:
https://doaj.org/article/f48ce7fcf38c4daba9e7f0e8ebffe07f
Publikováno v:
Journal of the Serbian Chemical Society, Vol 68, Iss 4-5, Pp 291-302 (2003)
Mixed tetraoxanes of the 4-phenyl-substituted cyclohexyl-spirotetraoxacyclohexyl-spirocholate series have been prepared and evaluated as possible antimalarials, antiproliferatives and antimycobacterials. The activity of the (4R or S)-phenyl series ag
Externí odkaz:
https://doaj.org/article/d82dc2305af2463e8dc9937057b8c3d3
Publikováno v:
Journal of the Serbian Chemical Society, Vol 67, Iss 7, Pp 465-471 (2002)
An intramolecular steroidal 1,2,4,5-tetraoxane has been synthesised in six steps starting from methyl 3-oxo-7a,12a-diacetoxy-5b-cholan-24-oate. The synthesised 1,2,4,5-tetraoxane has moderate in vitro antimalarial activity against P. falciparum strai
Externí odkaz:
https://doaj.org/article/268cf79a5a0d4a8cba11815377c2d081
Autor:
Natasa, Terzić, Dejan, Opsenica, Dragana, Milić, Bernard, Tinant, Kirsten S, Smith, Wilbur K, Milhous, Bogdan A, Solaja
Publikováno v:
Journal of medicinal chemistry. 50(21)
The synthesis of deoxycholic acid (DCA)- and cholic acid (CA)-derived mixed tetraoxanes revealed that N-(2-dimethylamino)ethyl derivatives are potent antimalarials in vitro and in vivo. The tetraoxanes presented in this paper are dual inhibitors: bes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fca68455ad787da435118a2e721ea6c
https://pubmed.ncbi.nlm.nih.gov/17887664
https://pubmed.ncbi.nlm.nih.gov/17887664
Autor:
Jelena Srbljanović, Branko Bobić, Tijana Štajner, Aleksandra Uzelac, Igor Opsenica, Nataša Terzić-Jovanović, Neda Bauman, Bogdan A. Šolaja, Olgica Djurković-Djaković
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 23, Iss , Pp 20-25 (2020)
Objectives: Malaria treatment is impeded by increasing resistance to conventional antimalarial drugs. Here we explored the activity of ten novel benzothiophene, thiophene and benzene aminoquinolines. Methods: In vitro testing was performed by the lac
Externí odkaz:
https://doaj.org/article/a8083033271840b78f4f33d4570fdeaa
Autor:
Rekha G. Panchal, Bogdan A. Šolaja, James C. Burnett, Cary Retterer, Sina Bavari, Brett Eaton, Života Selaković, Dejan Opsenica
Publikováno v:
Viruses, Vol 4, Iss 8, Pp 1279-1288 (2012)
Ebola (EBOV) and Marburg (MARV) filoviruses are highly infectious pathogens causing deadly hemorrhagic fever in humans and non-human primates. Promising vaccine candidates providing immunity against filoviruses have been reported. However, the sporad
Externí odkaz:
https://doaj.org/article/ba1728c095e74ae3a9c0a9ca0c508689
Autor:
DEJAN M. OPSENICA, BOGDAN A. ŠOLAJA
Publikováno v:
Journal of the Serbian Chemical Society, Vol 74, Iss 11, Pp 1155-1193 (2009)
The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5–2.7 million people. The World Health Organization (WHO) estimates that 90 % of these deaths occu
Externí odkaz:
https://doaj.org/article/7ff1defbe5334bed8f23931b3fb13075