Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Bogdan A. Luca"'
Autor:
Ion Sococol, Petru Mihai, Tudor-Cristian Petrescu, Florin Nedeff, Valentin Nedeff, Maricel Agop, Bogdan-Ionel Luca
Publikováno v:
Buildings, Vol 12, Iss 10, p 1525 (2022)
In the first part of the current study, the effectiveness of the transversal cross-section reduction method for RC beams in marginal areas (by means of mechanical drilling) was validated. The said method “encourages” the formation of plastic hing
Externí odkaz:
https://doaj.org/article/009de2a3be7c49db90e87f8d41dfc884
Autor:
Ajay Subramanian, Neda Nemat-Gorgani, Timothy J. Ellis-Caleo, David G.P. van IJzendoorn, Timothy J. Sears, Anish Somani, Bogdan A. Luca, Maggie Y. Zhou, Martina Bradic, Ileana A. Torres, Eniola Oladipo, Christin New, Deborah E. Kenney, Raffi S. Avedian, Robert J. Steffner, Michael S. Binkley, David G. Mohler, William D. Tap, Sandra P. D’Angelo, Matt van de Rijn, Kristen N. Ganjoo, Nam Q. Bui, Gregory W. Charville, Aaron M. Newman, Everett J. Moding
Publikováno v:
Cancer Research. 83:5960-5960
The tumor microenvironment contributes to tumorigenesis, disease progression, and response to therapy in soft tissue sarcomas (STSs). However, characterizing the malignant and stromal cells that make up STSs and correlating their abundance with clini
Autor:
Jeremy Clark, Bogdan-Alexandru Luca, Dylan R. Edwards, Vincent Moulton, Rosalin Cooper, Colin Cooper, Colin Campbell, Christopher Ellis, Daniel Brewer
Publikováno v:
British Journal of Cancer
Background Unsupervised learning methods, such as Hierarchical Cluster Analysis, are commonly used for the analysis of genomic platform data. Unfortunately, such approaches ignore the well-documented heterogeneous composition of prostate cancer sampl
Autor:
Alexander X. Lozano, Aadel A. Chaudhuri, Aishwarya Nene, Antonietta Bacchiocchi, Noah Earland, Matthew D. Vesely, Abul Usmani, Brandon E. Turner, Chloé B. Steen, Bogdan A. Luca, Ti Badri, Gunsagar S. Gulati, Milad R. Vahid, Farnaz Khameneh, Peter K. Harris, David Y. Chen, Kavita Dhodapkar, Mario Sznol, Ruth Halaban, Aaron M. Newman
Publikováno v:
Nat Med
Severe immune-related adverse events (irAEs) occur in up to 60% of patients with melanoma treated with immune checkpoint inhibitors (ICIs). However, it is unknown whether a common baseline immunological state precedes irAE development. Here we applie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975031290479ce416099f706a4316045
https://europepmc.org/articles/PMC8866214/
https://europepmc.org/articles/PMC8866214/
Autor:
John B. Sunwoo, Chen Chen, Imran A Mohammad, F. Christopher Holsinger, Michael J. Kaplan, Bogdan A. Luca, Andrew J. Gentles, June Ho Shin, Saumyaa Saumyaa, Uriel Y Moreno-Nieves, Fred M. Baik, Davud Sirjani, Gunsagar S. Gulati, Aaron M. Newman, Eben L. Rosenthal, Nikita Bedi, Nina Horowitz, Joshua K. Tay, Vasu Divi, Aharon G. Freud, David C Mundy, Serena Chang
Publikováno v:
Proc Natl Acad Sci U S A
Natural killer (NK) cells comprise one subset of the innate lymphoid cell (ILC) family. Despite reported antitumor functions of NK cells, their tangible contribution to tumor control in humans remains controversial. This is due to incomplete understa
Autor:
Maximilian Diehn, Bogdan A. Luca, Chih Long Liu, Mohammad Shahrokh Esfahani, Aaron M. Newman, Aadel A. Chaudhuri, David F. Steiner, Ash A. Alizadeh, Michael S. Khodadoust, Chloé B. Steen, Andrew J. Gentles, Florian Scherer
Publikováno v:
Nature biotechnology
Single-cell RNA-sequencing has emerged as a powerful technique for characterizing cellular heterogeneity, but it is currently impractical on large sample cohorts and cannot be applied to fixed specimens collected as part of routine clinical care. We
Autor:
Shea P. Connell, Colin Cooper, Bogdan-Alexandru Luca, Vincent Moulton, Daniel Brewer, Christopher Ellis
Publikováno v:
Genes
Genes, Vol 11, Iss 802, p 802 (2020)
Volume 11
Issue 7
Genes, Vol 11, Iss 802, p 802 (2020)
Volume 11
Issue 7
The highly heterogeneous clinical course of human prostate cancer has prompted the development of multiple RNA biomarkers and diagnostic tools to predict outcome for individual patients. Biomarker discovery is often unstable with, for example, small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7510c46d01ac8ec06168f16a9fdde8b5
https://ueaeprints.uea.ac.uk/id/eprint/76164/
https://ueaeprints.uea.ac.uk/id/eprint/76164/
Publikováno v:
Blood. 138:3259-3259
Background: Hematopoietic stem and progenitor cells (HSPCs) are capable of generating all human blood cells. Although these cells have been extensively evaluated using both sorted (Corces et al. Nat. Genet. 2016) and single cell assays (Pellin et al.
Autor:
Armon Azizi, Chih Long Liu, June Helen Myklebust, Aaron M. Newman, Bogdan A. Luca, Brian Sworder, David M. Kurtz, Chloé B. Steen, Yasodha Natkunam, Maximilian Diehn, Barzin Y. Nabet, Ranjana H. Advani, Farnaz Khameneh, Andrew J. Gentles, Mohammad Shahrokh Esfahani, Ash A. Alizadeh
Publikováno v:
Cancer Cell
Biological heterogeneity in diffuse large B cell lymphoma (DLBCL) is partly driven by cell-of-origin subtypes and associated genomic lesions, but also by diverse cell types and cell states in the tumor microenvironment (TME). However, dissecting thes
Autor:
Matt van de Rijn, Sushama Varma, Bogdan A. Luca, Magdalena Matusiak, Armon Azizi, Chunfang Zhu, Ash A. Alizadeh, Maximilian Diehn, Almudena Espín-Pérez, Joanna Przybyl, Chloé B. Steen, Aaron M. Newman, Andrew J. Gentles
Publikováno v:
Cell. 184:5482-5496.e28
Determining how cells vary with their local signaling environment and organize into distinct cellular communities is critical for understanding processes as diverse as development, aging, and cancer. Here we introduce EcoTyper, a machine learning fra