Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Bogdan A Danalache"'
Autor:
Marek Jankowski, Bogdan A Danalache, Eric Plante, Ahmed Menaouar, Maria Florian, Ju Jing Tan, Ryszard Grygorczyk, Tom L Broderick, Jolanta Gutkowska
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219205 (2019)
In the rat, oxytocin (OT) produces dose-dependent diuretic and natriuretic responses. Post-translational enzymatic conversion of the OT biosynthetic precursor forms both mature and C-terminally extended peptides. The plasma concentrations of these C-
Externí odkaz:
https://doaj.org/article/e514b943d6284392a20e364c2c53b396
Autor:
Bogdan A Danalache, Jolanta Gutkowska, Magdalena J Slusarz, Irena Berezowska, Marek Jankowski
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13643 (2010)
Oxytocin (OT), synthesized in the heart, has the ability to heal injured hearts and to promote cardiomyogenesis from stem cells. Recently, we reported that the OT-GKR molecule, a processing intermediate of OT, potently increased the spontaneous forma
Externí odkaz:
https://doaj.org/article/22975b2f8b2640d9904d1bd1ea57ed63
Autor:
Jean-Christophe Currie, Michel Demeule, Cyndia Charfi, Alain Zgheib, Alain Larocque, Bogdan Alexandru Danalache, Amira Ouanouki, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Cancers; Volume 14; Issue 8; Pages: 1877
Sortilin (SORT1) receptor-mediated endocytosis functions were exploited for this new approach for effective and safe treatments of gynecological cancers. Here, high expression of SORT1 was found in >75% of the clinically annotated ovarian and endomet
Autor:
Amira Ouanouki, Cyndia Charfi, Christian Marsolais, Alain Zgheib, Richard Béliveau, Bogdan Alexandru Danalache, Alain Larocque, Borhane Annabi, Jean-Christophe Currie, Michel Demeule
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
Vasculogenic mimicry (VM) is defined as the formation of microvascular channels by genetically deregulated cancer cells and is often associated with high tumor grade and cancer therapy resistance. This microcirculation system, independent of endothel
Autor:
Michel Demeule, Cyndia Charfi, Jean-Christophe Currie, Alain Zgheib, Bogdan Alexandru Danalache, Richard Béliveau, Christian Marsolais, Borhane Annabi
Publikováno v:
Pharmaceutics; Volume 14; Issue 9; Pages: 1910
Background: Breast and ovarian cancer stem cells (CSC) can contribute to the invasive and chemoresistance phenotype of tumors. TH1902, a newly developed sortilin (SORT1)-targeted peptide-docetaxel conjugate is currently in phase-1 clinical trial. Whe
Autor:
Ahmed Menaouar, Tom L. Broderick, Denis Yip, Bogdan A. Danalache, Jolanta Gutkowska, Jean-Louis Chiasson, Marek Jankowski, Eric Plante
Publikováno v:
Endocrinology. 156:1416-1428
Oxytocin (OT) is involved in the regulation of energy metabolism and in the activation of cardioprotective mechanisms. We evaluated whether chronic treatment with OT could prevent the metabolic and cardiac abnormalities associated with diabetes and o
Autor:
Jean-Louis Chiasson, Donghao Wang, Marek Jankowski, Jolanta Gutkowska, Daniel-Constantin Manolescu, Tom L. Broderick, Bogdan A. Danalache
Publikováno v:
Applied Physiology, Nutrition, and Metabolism. 39:1127-1136
In hypertensive rodents, retinoic acid (RA) prevents adverse cardiac remodelling and improves myocardial infarction outcome, but its role in obesity-related changes of cardiac tissue are unclear. We hypothesized that all-trans RA (ATRA) treatment wil
Autor:
Donghao Wang, Jolanta Gutkowska, Bogdan A. Danalache, Marek Jankowski, Ahmed Menaouar, Maria Florian
Publikováno v:
International Journal of Cardiology. 175:38-49
Background Oxytocin (OT) and functional OT receptor (OTR) are expressed in the heart and are involved in blood pressure regulation and cardioprotection. Cardiac OTR signaling is associated with atrial natriuretic peptide (ANP) and nitric oxide (NO) r
Publikováno v:
Journal of Endocrinology. 220:277-289
The functional oxytocin (OT) system is expressed in the human and rodent hearts. OT stimulates differentiation of cardiac stem cells into contracting cardiomyocytes (CM). In this study, we investigated OT receptors (OTR) expressed in the cells of car
Autor:
Babbette LaMarca, Bogdan A. Danalache, Donghao Wang, Jolanta Gutkowska, Joey P. Granger, Marek Jankowski
Publikováno v:
Journal of Hypertension. 29:1203-1212
Chronic reduction of uteroplacental perfusion pressure (RUPP) in pregnant rats leads to placental ischemia, maternal endothelial cell dysfunction, hypertension and elevated levels of tumor necrosis factor-alpha (TNF-α). In this study we investigated