Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Bogdan‐Tiberius Preca"'
Autor:
Victor O. Oria, Paul Lopatta, Tatjana Schmitz, Bogdan‐Tiberius Preca, Alexander Nyström, Catharina Conrad, Jörg W. Bartsch, Birte Kulemann, Jens Hoeppner, Jochen Maurer, Peter Bronsert, Oliver Schilling
Publikováno v:
Molecular Oncology, Vol 13, Iss 2, Pp 456-479 (2019)
A disintegrin and a metalloprotease (ADAM)‐9 is a metzincin cell‐surface protease with strongly elevated expression in solid tumors, including pancreatic ductal adenocarcinoma (PDAC). In this study, we performed immunohistochemistry (IHC) of a ti
Externí odkaz:
https://doaj.org/article/d133eeafa0c9469aa43b42ea0531f39a
Autor:
Mohit Kumar Jolly, Bogdan-Tiberius Preca, Satyendra C. Tripathi, Dongya Jia, Jason T. George, Samir M. Hanash, Thomas Brabletz, Marc P. Stemmler, Jochen Maurer, Herbert Levine
Publikováno v:
APL Bioengineering, Vol 2, Iss 3, Pp 031908-031908-15 (2018)
Aberrant activation of epithelial-mesenchymal transition (EMT) in carcinoma cells contributes to increased migration and invasion, metastasis, drug resistance, and tumor-initiating capacity. EMT is not always a binary process; rather, cells may ex
Externí odkaz:
https://doaj.org/article/c76b40ef86644f9293995f0065b30e0d
Autor:
Simone Meidhof, Simone Brabletz, Waltraut Lehmann, Bogdan‐Tiberius Preca, Kerstin Mock, Manuel Ruh, Julia Schüler, Maria Berthold, Anika Weber, Ulrike Burk, Michael Lübbert, Martin Puhr, Zoran Culig, Ulrich Wellner, Tobias Keck, Peter Bronsert, Simon Küsters, Ulrich T Hopt, Marc P Stemmler, Thomas Brabletz
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 6, Pp 831-847 (2015)
Abstract Therapy resistance is a major clinical problem in cancer medicine and crucial for disease relapse and progression. Therefore, the clinical need to overcome it, particularly for aggressive tumors such as pancreatic cancer, is very high. Aberr
Externí odkaz:
https://doaj.org/article/86d69cdad4a84da692d75fa5e3c574a3
Autor:
Milica Vulin, Charly Jehanno, Atul Sethi, Ana Luísa Correia, Milan M. S. Obradović, Joana Pinto Couto, Marie-May Coissieux, Maren Diepenbruck, Bogdan-Tiberius Preca, Katrin Volkmann, Priska Auf der Maur, Alexander Schmidt, Simone Münst, Loïc Sauteur, Michal Kloc, Marta Palafox, Adrian Britschgi, Vincent Unterreiner, Olaf Galuba, Isabelle Claerr, Sandra Lopez-Romero, Giorgio G. Galli, Daniel Baeschlin, Ryoko Okamoto, Savas D. Soysal, Robert Mechera, Walter P. Weber, Thomas Radimerski, Mohamed Bentires-Alj
Publikováno v:
Oncogene. 41:4459-4473
Plasticity delineates cancer subtypes with more or less favourable outcomes. In breast cancer, the subtype triple-negative lacks expression of major differentiation markers, e.g., estrogen receptor α (ERα), and its high cellular plasticity results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63aa2dd9501f2424f301e979d8bdcf8
https://doi.org/10.1038/s41388-022-02429-0
https://doi.org/10.1038/s41388-022-02429-0
Autor:
Roland Schüle, Jochen Maurer, Toufike Kanouni, Jeffrey A. Stafford, Michael B. Wallace, Jiangchun Xu, Elmar Stickeler, Melanie Boerries, Marie Follo, Amelie Proske, Peter Bronsert, Nicola Iovino, Fides Zenk, Anita Allen, Dominica Willmann, Sylvia Urban, Bogdan-Tiberius Preca, Juliane Strietz, Stella S. Stepputtis, Eric Metzger
This file contains the legends to all Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5761318b1f6435dcbf3e792e5a2fa818
https://doi.org/10.1158/0008-5472.22419060.v1
https://doi.org/10.1158/0008-5472.22419060.v1
Autor:
Roland Schüle, Jochen Maurer, Toufike Kanouni, Jeffrey A. Stafford, Michael B. Wallace, Jiangchun Xu, Elmar Stickeler, Melanie Boerries, Marie Follo, Amelie Proske, Peter Bronsert, Nicola Iovino, Fides Zenk, Anita Allen, Dominica Willmann, Sylvia Urban, Bogdan-Tiberius Preca, Juliane Strietz, Stella S. Stepputtis, Eric Metzger
H3K9me3 levels increase upon treatment with QC6352. Changes in H3K9me3 levels are depicted according to genomic location.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03971b883243e51d248ae86c72123875
https://doi.org/10.1158/0008-5472.22419069
https://doi.org/10.1158/0008-5472.22419069
Autor:
Roland Schüle, Jochen Maurer, Toufike Kanouni, Jeffrey A. Stafford, Michael B. Wallace, Jiangchun Xu, Elmar Stickeler, Melanie Boerries, Marie Follo, Amelie Proske, Peter Bronsert, Nicola Iovino, Fides Zenk, Anita Allen, Dominica Willmann, Sylvia Urban, Bogdan-Tiberius Preca, Juliane Strietz, Stella S. Stepputtis, Eric Metzger
Traditional treatments for breast cancer fail to address therapy-resistant cancer stem–like cells that have been characterized by changes in epigenetic regulators such as the lysine demethylase KDM4. Here, we describe an orally available, selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::568147c1824ce1c828b615cb332bfec3
https://doi.org/10.1158/0008-5472.c.6510285.v1
https://doi.org/10.1158/0008-5472.c.6510285.v1
Autor:
Bogdan-Tiberius Preca, Veit Hornung, Félicie Cottard, Manfred Jung, Axel Imhof, Eric Metzger, Manuela Sum, Dominica Willmann, Roland Schüle, Nadine Obier, Oliver Einsle, Sven Perner, Anne Offermann, Sheng Wang, Holger Greschik, Bianca Hermann, Andreas Schmidt, Svenja Ulferts, Jochen Maurer, Sylvia Urban, Anita Allen
Publikováno v:
Nature Structural & Molecular Biology. 26:361-371
Histone lysine methylation is generally performed by SET domain methyltransferases and regulates chromatin structure and gene expression. Here, we identify human C21orf127 (HEMK2, N6AMT1, PrmC), a member of the seven-β-strand family of putative meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac5fa1eb17e5b0be945d146945d442b
https://doi.org/10.1038/s41594-019-0219-9
https://doi.org/10.1038/s41594-019-0219-9
Autor:
Anita Allen, Marie Follo, Sylvia Urban, Roland Schüle, Jochen Maurer, Stella S. Stepputtis, Melanie Boerries, Jeffrey A. Stafford, Dominica Willmann, Peter Bronsert, Fides Zenk, Toufike Kanouni, Juliane Strietz, Michael Brennan Wallace, Nicola Iovino, Jiangchun Xu, Eric Metzger, Amelie Proske, Bogdan-Tiberius Preca, Elmar Stickeler
Publikováno v:
Cancer research : an official organ of the American Association for Cancer Research
Traditional treatments for breast cancer fail to address therapy-resistant cancer stem–like cells that have been characterized by changes in epigenetic regulators such as the lysine demethylase KDM4. Here, we describe an orally available, selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18faf2c56e13e4f3bac3203fa6f72d10
https://doi.org/10.1158/0008-5472.can-17-1754
https://doi.org/10.1158/0008-5472.can-17-1754
ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer
Autor:
Juliane Strietz, Qingyan Au, Melanie Boerries, Mihee M. Kim, Jochen Maurer, Stella S. Stepputtis, Robert G. Oshima, David J. Castro, Peter Bronsert, Elmar Stickeler, Bernhard Kuster, Pedro Aza-Blanc, Thomas Brabletz, Bogdan-Tiberius Preca, Susanne Heynen-Genel, Corinne Vannier, Hauke Busch
Publikováno v:
OncoTarget 7(50), 83278-83293 (2016). doi:10.18632/oncotarget.13086
Oncotarget
Oncotarget
OncoTarget 7(50), 83278-83293 (2016). doi:10.18632/oncotarget.13086
Published by Impact Journals LLC, [S.l.]
Published by Impact Journals LLC, [S.l.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7aae62df7d0a56f08787e4d3bde8f80
https://doi.org/10.18632/oncotarget.13086
https://doi.org/10.18632/oncotarget.13086