Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Bogang Wu"'
Autor:
Bogang Wu, Xiaowen Zhang, Huai-Chin Chiang, Haihui Pan, Bin Yuan, Payal Mitra, Leilei Qi, Hayk Simonyan, Colin N. Young, Eric Yvon, Yanfen Hu, Nu Zhang, Rong Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Negative elongation factor B (NELFB) is one of the four subunits of the NELF complex that controls RNA polymerase II pausing. Here the authors show that, by associating with the key T cell transcription factor TCF1, NELFB is required for eliciting CD
Externí odkaz:
https://doaj.org/article/2778d1c82b674868ad6b34ca40a859a4
Autor:
Rong Li, Xiaowen Zhang, Bogang Wu, Yanfen Hu, Anelia Horvath, Claudine Isaacs, Yidong Chen, Leilei Qi, Huai-Chin Chiang, Haihui Pan, Alexandra Greenbaum, Elizabeth Stark, Li-Ju Wang, Bassem R. Haddad, Dionyssia Clagett, Richard Elledge
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Women with BRCA1 germline mutations have approximately an 80% lifetime chance of developing breast cancer. While the tumor suppressor function of BRCA1 in breast epithelium has been studied extensively, it is not clear whether BRCA1 deficiency in non
Externí odkaz:
https://doaj.org/article/eb98d1b26ddb49bfbcad17cbfb1f7623
Autor:
Deyi Zhang, Ryan M. Reyes, Erica Osta, Suresh Kari, Harshita B. Gupta, Alvaro S. Padron, Anand V. R. Kornepati, Aravind Kancharla, Xiujie Sun, Yilun Deng, Bogang Wu, Ratna Vadlamudi, Rong Li, Robert S. Svatek, Tyler J. Curiel
Publikováno v:
Cancer Medicine, Vol 10, Iss 6, Pp 2137-2152 (2021)
Abstract Tumor cell‐intrinsic programmed death‐ligand 1 (PD‐L1) signals mediate immunopathologic effects in breast, colon, and ovarian cancers and in melanomas, but bladder cancer (BC) effects are unreported. We show here that BC cell‐intrins
Externí odkaz:
https://doaj.org/article/e4a5d1a873db407eb7004100b7129f12
Autor:
Jing Yang, Rong Li, Bin Yuan, Curtis A Clark, Bogang Wu, Justin M Drerup, Tianbao Li, Victor X Jin, Yanfen Hu, Tyler J Curiel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
BackgroundThe non-overlapping functions of the two estrogen receptor subtypes, ERα (Estrogen Receptor α)and ERβ (Estrogen Receptor β), in tumor cells have been studied extensively. However, their counterparts in host cells is vastly underinterrog
Externí odkaz:
https://doaj.org/article/9a99bc7f4fa646ec8701df65ded1023e
Autor:
Rong Li, Bin Yuan, Bogang Wu, Yanfen Hu, Tyler J Curiel, Huai-Chin Chiang, Xiujie Sun, Payal Mitra
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
The programmed death-ligand 1 (PD-L1)-dependent immune checkpoint attenuates host immunity and maintains self-tolerance. Imbalance between protective immunity and immunopathology due to altered PD-L1 signaling can lead to autoimmunity or tumor immuno
Externí odkaz:
https://doaj.org/article/e4793b49487a45ad8664d5c4cfef8955
Autor:
Bogang Wu, Xiujie Sun, Harshita B. Gupta, Bin Yuan, Jingwei Li, Fei Ge, Huai-Chin Chiang, Xiaowen Zhang, Chi Zhang, Deyi Zhang, Jing Yang, Yanfen Hu, Tyler J. Curiel, Rong Li
Publikováno v:
OncoImmunology, Vol 7, Iss 11 (2018)
Programmed death-ligand 1 (PD-L1) and its receptor programmed cell death protein 1 (PD-1) modulate antitumor immunity and are major targets of checkpoint blockade immunotherapy. However, clinical trials of anti-PD-L1 and anti-PD-1 antibodies in breas
Externí odkaz:
https://doaj.org/article/967aa3a780764179b5178d62740cb693
Autor:
Bogang Wu, Leif W. Ellisen
Publikováno v:
Cancer Cell. 40:1276-1278
A recent Nature study delineates a stepwise genomic evolution during pancreatic cancer development, employing an engineered mutant Kras and heterozygous Trp53 mouse model that identifies cells undergoing Trp53 loss of heterozygosity (LOH). Genetic pr
Autor:
Ryan Reyes, Robert S. Svatek, Anand Kornepati, Suresh Kari, Ratna K. Vadlamudi, Tyler J. Curiel, Erica Osta, Yilun Deng, Bogang Wu, Deyi Zhang, Alvaro Padron, Xiujie Sun, Rong Li, Harshita Gupta, Aravind Kancharla
Publikováno v:
Cancer Medicine, Vol 10, Iss 6, Pp 2137-2152 (2021)
Cancer Medicine
Cancer Medicine
Tumor cell‐intrinsic programmed death‐ligand 1 (PD‐L1) signals mediate immunopathologic effects in breast, colon, and ovarian cancers and in melanomas, but bladder cancer (BC) effects are unreported. We show here that BC cell‐intrinsic PD‐L
Autor:
Yangai Liu, Minghao Fang, Xiaoguang Zhang, Xin Min, Yunfei Xu, Xiaowen Wu, Zhaohui Huang, Tengteng Shi, Guo Chen, Bogang Wu
Publikováno v:
Energy & Fuels. 35:877-882
The development of flexible smart phase change fibers has been limited because of the low production rate and safety concerns of electrospinning. Therefore, a novel centrifugal spinning technology,...
Publikováno v:
Cancers. 15:1278
Antibody–drug conjugates (ADCs), with antibodies targeted against specific antigens linked to cytotoxic payloads, offer the opportunity for a more specific delivery of chemotherapy and other bioactive payloads to minimize side effects. First approv