Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Boer, Li"'
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Background Controlling the adipo-osteogenic lineage commitment of bone marrow mesenchymal stem cell (BMSC) in favor of osteogenesis is considered a promising approach for bone regeneration and repair. Accumulating evidence indicates that oxi
Externí odkaz:
https://doaj.org/article/618e0db723b041408e969e5e6531452e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The imbalance between bone formation and bone resorption causes osteoporosis, which leads to severe bone fractures. It is known that increases in osteoclast numbers and activities are the main reasons for increasing bone resorption. Although extensiv
Externí odkaz:
https://doaj.org/article/88aaefed3a2b467fa561c0d5901f24fe
Akademický článek
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Publikováno v:
Journal of Cellular and Molecular Medicine
Emerging evidence indicates extensive oxidative stress is a consequence of obesity which impairs bone formation. Glutathione peroxidase 7 (GPX7) is a conserved endoplasmic reticulum (ER) retention protein, lacking of which causes accumulation of reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e69e668a4517f657b4f4a8fe2ba4ec
https://doi.org/10.1111/jcmm.16974
https://doi.org/10.1111/jcmm.16974
Akademický článek
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Publikováno v:
The FASEB Journal. 34:11058-11067
Excessive bone resorption over bone formation is the root cause for bone loss leading to osteoporotic fractures. Development of new antiresorptive therapies calls for a holistic understanding of osteoclast differentiation and function. Although much
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2469ad1b1d9cb53eca010be8ffc12326
https://doi.org/10.1096/fj.202000771r
https://doi.org/10.1096/fj.202000771r
Publikováno v:
Stem cell researchtherapy. 13(1)
Controlling the adipo-osteogenic lineage commitment of bone marrow mesenchymal stem cell (BMSC) in favor of osteogenesis is considered a promising approach for bone regeneration and repair. Accumulating evidence indicates that oxidative phosphorylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ff34dc7de81f736945ea36b84aee7e2
https://pubmed.ncbi.nlm.nih.gov/35193674
https://pubmed.ncbi.nlm.nih.gov/35193674
Akademický článek
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Publikováno v:
Drug discovery today. 26(5)
Reactive oxygen species (ROS) have emerged as key players in regulating the fate and function of stem cells from both non-hematopoietic and hematopoietic lineages in bone marrow, and thus affect the osteoblastogenesis-osteoclastogenesis balance and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b15c89e47d3aea4ea2e0ef5a17ab299a
https://pubmed.ncbi.nlm.nih.gov/33684524
https://pubmed.ncbi.nlm.nih.gov/33684524
Autor:
Xing Ji, E. Dale Abel, Wen-Chih Lee, Boer Li, Wei Huang, Fanxin Long, Dianming Jiang, Hong Chen, Yu Shi
Wingless/integrated (Wnt) signaling has emerged as a major mechanism for promoting bone formation and a target pathway for developing bone anabolic agents against osteoporosis. However, the downstream events mediating the potential therapeutic effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ee3d74c6137230507070f5cd3689b0
https://europepmc.org/articles/PMC6593878/
https://europepmc.org/articles/PMC6593878/
