Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Boel, Brynedal"'
Autor:
Hrafnhildur Gudjonsdottir, Per Tynelius, Nouha Saleh Stattin, Diego Yacamán Méndez, Anton Lager, Boel Brynedal
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Undiagnosed type 2 diabetes (T2D) is a global problem. Current strategies for diagnosis in Sweden include screening individuals within primary healthcare who are of high risk, such as those with hypertension, obesity, prediabetes,
Externí odkaz:
https://doaj.org/article/eebf2c1279864f948d4afc8d3d78cee6
Autor:
Anders Norrman, Jan Hasselström, Gunnar Ljunggren, Caroline Wachtler, Julia Eriksson, Thomas Kahan, Per Wändell, Hrafnhildur Gudjonsdottir, Sebastian Lindblom, Toralph Ruge, Andreas Rosenblad, Boel Brynedal, Axel C. Carlsson
Publikováno v:
Preventive Medicine Reports, Vol 44, Iss , Pp 102806- (2024)
Background: Many individuals with hypertension remain undiagnosed. We aimed to develop a predictive model for hypertension using diagnostic codes from prevailing electronic medical records in Swedish primary care. Methods: This sex- and age-matched c
Externí odkaz:
https://doaj.org/article/f4971ca4f0e94428bb073e82fa806338
Autor:
Åsa K. Hedman, Eitan Winter, Niyaz Yoosuf, Yair Benita, Louise Berg, Boel Brynedal, Lasse Folkersen, Lars Klareskog, Mateusz Maciejewski, Alexandra Sirota-Madi, Yael Spector, Daniel Ziemek, Leonid Padyukov, Shai S. Shen-Orr, Scott A. Jelinsky
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Rheumatoid arthritis (RA) is an autoimmune disease characterized by systemic inflammation and is mediated by multiple immune cell types. In this work, we aimed to determine the relevance of changes in cell proportions in peripheral blood mon
Externí odkaz:
https://doaj.org/article/015c0a27681d422fa2a149b768171efd
Autor:
Diego Yacamán Méndez, Minhao Zhou, Ylva Trolle Lagerros, Donaji V. Gómez Velasco, Per Tynelius, Hrafnhildur Gudjonsdottir, Antonio Ponce de Leon, Katarina Eeg-Olofsson, Claes-Göran Östenson, Boel Brynedal, Carlos A. Aguilar Salinas, David Ebbevi, Anton Lager
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The prevention of type 2 diabetes is challenging due to the variable effects of risk factors at an individual level. Data-driven methods could be useful to detect more homogeneous groups based on risk factor variability. The aim o
Externí odkaz:
https://doaj.org/article/c8141b01db0242c6b7af60f0f4721601
Autor:
Boel Brynedal, Niyaz Yoosuf, Tinna Bjorg Ulfarsdottir, Daniel Ziemek, Mateusz Maciejewski, Lasse Folkersen, Helga Westerlind, Malin Müller, Peter Sahlström, Scott A. Jelinsky, Aase Hensvold, Leonid Padyukov, Nancy Vivar Pomiano, Anca Catrina, Lars Klareskog, Louise Berg
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundMethotrexate (MTX) is the first line treatment for rheumatoid arthritis (RA), but failure of satisfying treatment response occurs in a significant proportion of patients. Here we present a longitudinal multi-omics study aimed at detecting m
Externí odkaz:
https://doaj.org/article/75fb2c0635c442d4bc63cec8b8b58bca
Autor:
Ainhoa Bereziartua, Jie Chen, Kees de Hoogh, Sophia Rodopoulou, Zorana J. Andersen, Tom Bellander, Jørgen Brandt, Daniela Fecht, Francesco Forastiere, John Gulliver, Ole Hertel, Barbara Hoffmann, Ulla Arthur Hvidtfeldt, W.M.Monique Verschuren, Karl-Heinz Jöckel, Jeanette T Jørgensen, Klea Katsouyanni, Matthias Ketzel, Norun Hjertager Krog, Boel Brynedal, Karin Leander, Shuo Liu, Petter Ljungman, Elodie Faure, Patrik K.E. Magnusson, Gabriele Nagel, Göran Pershagen, Annette Peters, Ole Raaschou-Nielsen, Matteo Renzi, Debora Rizzuto, Evangelia Samoli, Yvonne T. van der Schouw, Sara Schramm, Gianluca Severi, Massimo Stafoggia, Maciej Strak, Mette Sørensen, Anne Tjønneland, Gudrun Weinmayr, Kathrin Wolf, Emanuel Zitt, Bert Brunekreef, Gerard Hoek
Publikováno v:
Environment International, Vol 166, Iss , Pp 107341- (2022)
Background: The majority of studies have shown higher greenness exposure associated with reduced mortality risks, but few controlled for spatially correlated air pollution and traffic noise exposures. We aim to address this research gap in the ELAPSE
Externí odkaz:
https://doaj.org/article/be2d88da736544ee8ae1e0cd740750e8
Autor:
Natalia Sherina, Charlotte de Vries, Nastya Kharlamova, Natalie Sippl, Xia Jiang, Boel Brynedal, Elin Kindstedt, Monika Hansson, Linda Mathsson-Alm, Lena Israelsson, Ragnhild Stålesen, Saedis Saevarsdottir, Rikard Holmdahl, Aase Hensvold, Gunnar Johannsen, Kaja Eriksson, Federica Sallusto, Anca I. Catrina, Johan Rönnelid, Caroline Grönwall, Tülay Yucel-Lindberg, Lars Alfredsson, Lars Klareskog, Luca Piccoli, Vivianne Malmström, Khaled Amara, Karin Lundberg
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Based on the epidemiological link between periodontitis and rheumatoid arthritis (RA), and the unique feature of the periodontal bacterium Porphyromonas gingivalis to citrullinate proteins, it has been suggested that production of anti-citrullinated
Externí odkaz:
https://doaj.org/article/526e09f1b5cb4ce898b6e91a70579ed3
Autor:
Evan Reed, Anna Karin Hedström, Monika Hansson, Linda Mathsson-Alm, Boel Brynedal, Saedis Saevarsdottir, Martin Cornillet, Per-Johan Jakobsson, Rikard Holmdahl, Karl Skriner, Guy Serre, Lars Alfredsson, Johan Rönnelid, Karin Lundberg
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-11 (2020)
Abstract Background Rheumatoid arthritis (RA) is classified as seropositive or seronegative, depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti-citrullinated protein antibodies (ACPA), commonly detected using a
Externí odkaz:
https://doaj.org/article/9e44246f67784c6896472dab7aa00d19
Autor:
Mikael V. Ringh, Michael Hagemann-Jensen, Maria Needhamsen, Lara Kular, Charles E. Breeze, Louise K. Sjöholm, Lara Slavec, Susanna Kullberg, Jan Wahlström, Johan Grunewald, Boel Brynedal, Yun Liu, Malin Almgren, Maja Jagodic, Johan Öckinger, Tomas J. Ekström
Publikováno v:
EBioMedicine, Vol 46, Iss , Pp 290-304 (2019)
Background: While smoking is known to associate with development of multiple diseases, the underlying mechanisms are still poorly understood. Tobacco smoking can modify the chemical integrity of DNA leading to changes in transcriptional activity, par
Externí odkaz:
https://doaj.org/article/1cafb6ec21624987acffe696bc1a2a84
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250282 (2021)
Understanding the genetic background of complex diseases requires the expansion of studies beyond univariate associations. Therefore, it is important to use interaction assessments of risk factors in order to discover whether, and how genetic risk va
Externí odkaz:
https://doaj.org/article/f54881593d8a4db68d5fd19b3b9cddc3