Increasing the number and intensity of shock tube generated blast waves leads to earlier retinal ganglion cell dysfunction and regional cell death.

Autor: Harper MM; Department of Ophthalmology and Visual Sciences, The University of Iowa, Iowa City, IA, USA; Department of Biology, The University of Iowa, Iowa City, IA, USA; Veterans Administration Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, Iowa City, IA, USA. Electronic address: matthew-harper@uiowa.edu., Boehme NA; Veterans Administration Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, Iowa City, IA, USA., Dutca L; Veterans Administration Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, Iowa City, IA, USA., Navarro V; Veterans Administration Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, Iowa City, IA, USA.

Publikováno v: Experimental eye research [Exp Eye Res] 2024 Feb; Vol. 239, pp. 109754. Date of Electronic Publication: 2023 Dec 17.

Axonopathy precedes cell death in ocular damage mediated by blast exposure.

Autor: Boehme NA; Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, 601 Hwy 6 W (151), Iowa City, IA, 52772, USA.; Department of Ophthalmology and Visual Science, The University of Iowa, Iowa City, IA, USA., Hedberg-Buenz A; Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, 601 Hwy 6 W (151), Iowa City, IA, 52772, USA.; Department of Molecular Physiology and Biophysics, The University of Iowa, Iowa City, IA, USA., Tatro N; Department of Ophthalmology and Visual Science, The University of Iowa, Iowa City, IA, USA.; Institute for Vision Research, The University of Iowa, Iowa City, IA, USA., Bielecki M; Department of Ophthalmology and Visual Science, The University of Iowa, Iowa City, IA, USA., Castonguay WC; Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, 601 Hwy 6 W (151), Iowa City, IA, 52772, USA.; Department of Molecular Physiology and Biophysics, The University of Iowa, Iowa City, IA, USA., Scheetz TE; Department of Ophthalmology and Visual Science, The University of Iowa, Iowa City, IA, USA.; Institute for Vision Research, The University of Iowa, Iowa City, IA, USA., Anderson MG; Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, 601 Hwy 6 W (151), Iowa City, IA, 52772, USA.; Department of Ophthalmology and Visual Science, The University of Iowa, Iowa City, IA, USA.; Department of Molecular Physiology and Biophysics, The University of Iowa, Iowa City, IA, USA.; Institute for Vision Research, The University of Iowa, Iowa City, IA, USA., Dutca LM; Center for the Prevention and Treatment of Visual Loss, Iowa City VA Healthcare System, 601 Hwy 6 W (151), Iowa City, IA, 52772, USA. laura-dutca@uiowa.edu.; Department of Ophthalmology and Visual Science, The University of Iowa, Iowa City, IA, USA. laura-dutca@uiowa.edu.

Publikováno v: Scientific reports [Sci Rep] 2021 Jun 03; Vol. 11 (1), pp. 11774. Date of Electronic Publication: 2021 Jun 03.