Voltage-gated sodium channels contribute to action potentials and spontaneous contractility in isolated human lymphatic vessels

Autor: Telinius, Niklas, Majgaard, Jens, Kim, Sukhan, Katballe, Niels, Pahle, Einar, Nielsen, Jørn, Hjortdal, Vibeke, Aalkjaer, Christian, Boedtkjer, Donna Briggs

Publikováno v: Telinius, N, Majgaard, J, Kim, S, Katballe, N, Pahle, E, Nielsen, J, Hjortdal, V, Aalkjaer, C & Bødtkjer, D M B 2015, ' Voltage-gated sodium channels contribute to action potentials and spontaneous contractility in isolated human lymphatic vessels ', The Journal of Physiology, vol. 593, no. 14, pp. 3109-3122 . https://doi.org/10.1113/JP270166

Voltage-gated sodium channels (VGSC) play a key role for initiating action potentials (AP) in excitable cells. VGSC in human lymphatic vessels have not been investigated. In this study we describe the electrical activity and action potentials of smal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::27e40154f82abfe30ed4cea63c4a38d3
https://pure.au.dk/portal/da/publications/voltagegated-sodium-channels-contribute-to-action-potentials-and-spontaneous-contractility-in-isolated-human-lymphatic-vessels(6499fd02-fba4-43b4-8490-95a52ad561fb).html

Human lymphatic vessel contractile activity is inhibited in vitro but not in vivo by the calcium channel blocker nifedipine

Autor: Telinius, Niklas, Mohanakumar, Sheyanth, Majgaard, Jens, Kim, Sukhan, Pilegaard, Hans, Pahle, Einar, Nielsen, Jørn, de Leval, Marc, Aalkjaer, Christian, Hjortdal, Vibeke, Boedtkjer, Donna Briggs

Publikováno v: Telinius, N, Mohanakumar, S, Majgaard, J, Kim, S, Pilegaard, H, Pahle, E, Nielsen, J, de Leval, M, Aalkjaer, C, Hjortdal, V & Boedtkjer, D B 2014, ' Human lymphatic vessel contractile activity is inhibited in vitro but not in vivo by the calcium channel blocker nifedipine ', The Journal of Physiology, vol. 592, no. 21, pp. 4697-4714 . https://doi.org/10.1113/jphysiol.2014.276683

Calcium channel blockers (CCB) are widely-prescribed anti-hypertensive agents. The commonest side-effect, peripheral oedema, is attributed to a larger arterial than venous dilation causing increased fluid filtration. Whether CCB treatment is detrimen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::654b4cdfc2826434c3e4d92ad01e3fa9
https://pure.au.dk/portal/da/publications/human-lymphatic-vessel-contractile-activity-is-inhibited-in-vitro-but-not-in-vivo-by-the-calcium-channel-blocker-nifedipine(ae402f82-5614-43a1-b449-01ac0985f40a).html

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.