A Method for Modeling Growth of Organs and Transplants Based on the General Growth Law: Application to the Liver in Dogs and Humans

Autor: Ivo F. Sbalzarini, Yuri K. Shestopaloff

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e99275 (2014)
PLoS ONE

Understanding biological phenomena requires a systemic approach that incorporates different mechanisms acting on different spatial and temporal scales, since in organisms the workings of all components, such as organelles, cells, and organs interrela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a57448ca27c311a328cb0f7d591ac2
http://arxiv.org/abs/1509.03513

pix-1 Controls Early Elongation in Parallel with mel-11 and let-502 in Caenorhabditis elegans

Autor: Emmanuel Martin, Bernard Nkengfac, Sarah Jenna, Mathieu Neault, Sharon Harel, Karim Hamiche

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e94684 (2014)

Cell shape changes are crucial for metazoan development. During Caenorhabditis elegans embryogenesis, epidermal cell shape changes transform ovoid embryos into vermiform larvae. This process is divided into two phases: early and late elongation. Earl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9b617ae917b329ffb6d2371dfc8ec4
http://europepmc.org/articles/PMC3986101

Dynamic association with donor cell filopodia and lipid-modification are essential features of Wnt8a during patterning of the zebrafish neuroectoderm

Autor: Muriel Rhinn, Stephanie Spannl-Müller, Gilbert Weidinger, Michael Brand, Birgit Kagermeier-Schenk, Gunes Ozhan, Marta Luz

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e84922 (2014)
PLoS ONE

BackgroundWnt proteins are conserved signaling molecules that regulate pattern formation during animal development. Many Wnt proteins are post-translationally modified by addition of lipid adducts. Wnt8a provides a crucial signal for patterning the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72de345d7ce983d408eb85b9ecdf5679
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24427298/?tool=EBI

Endoplasmic reticulum stress-unfolding protein response-apoptosis cascade causes chondrodysplasia in a col2a1 p.Gly1170Ser mutated mouse model

Autor: Peiqiang Su, Anjing Liang, Di Huang, Zizhao Wu, Yan Peng, Wei Ye, Chengjie Lian, Guoyan Liang, Dongsheng Huang, Wenjie Gao

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e86894 (2014)
PLoS ONE

The collagen type II alpha 1 (COL2A1) mutation causes severe skeletal malformations, but the pathogenic mechanisms of how this occurs are unclear. To understand how this may happen, a col2a1 p.Gly1170Ser mutated mouse model was constructed and in hom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6b4b19954afd1aed8170399292e00a
http://europepmc.org/articles/PMC3903611?pdf=render

Evidence for Involvement of Wnt Signalling in Body Polarities, Cell Proliferation, and the Neuro-Sensory System in an Adult Ctenophore

Autor: Hervé Le Guyader, Antoine Mialot, Michaël Manuel, Cyrielle Dayraud, Muriel Jager, Eric Quéinnec

Publikováno v: PLoS ONE
PLoS ONE, 2013, 8 (12), pp.e84363. ⟨10.1371/journal.pone.0084363⟩
PLoS ONE, Vol 8, Iss 12, p e84363 (2013)
PLoS ONE, Public Library of Science, 2013, 8 (12), pp.e84363. ⟨10.1371/journal.pone.0084363⟩

International audience; Signalling through the Wnt family of secreted proteins originated in a common metazoan ancestor and greatly influenced the evolution of animal body plans. In bilaterians, Wnt signalling plays multiple fundamental roles during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0da049769915d8f08ad3ed38e0374f6
https://hal.science/hal-01544483