Zobrazeno 1 - 10 of 121 pro vyhledávání: '"Body Composition/genetics"'
1
Disentangling the genetics of lean mass
Autor: Tuomas O. Kilpeläinen, Jacqueline S. L. Kloth, Nam H. Cho, Peter Vollenweider, Georg Homuth, Unnur Thorsteinsdottir, Nicole C. Wright, Wen-Chi Chou, Yongmei Liu, Kari Stefansson, Kim M. Huffman, Ida Malkin, Andrew P. Morris, Robert Luben, Shad B. Smith, Lei Yu, Joel Eriksson, Aarno Palotie, Veikko Salomaa, Michael J. Econs, Liesbeth Vandenput, Elizabeth A. Streeten, Albert Hofman, Elisabeth Widen, Emmi Tikkanen, Braxton D. Mitchell, Natasja M. van Schoor, Caroline Hayward, Liisa Byberg, Joanne M. Jordan, Bruce M. Psaty, Elisabeth Steinhagen-Thiessen, Magnus Karlsson, Harry Campbell, John C. Chambers, Fernando Rivadeneira, Johan G. Eriksson, Jari Lahti, Reiner Biffar, James F. Wilson, Luda Diatchenko, Jerome I. Rotter, Eric S. Orwoll, Launer J. Lenore, Cornelia M. van Duijn, Frances M K Williams, Munro Peacock, David A. Bennett, Annette Peters, Ali A. Aghdassi, Gudny Eiriksdottir, Weihua Zhang, Östen Ljunggren, Daniel L. Koller, Nicole Soranzo, Patricia A. Thompson, Jane A. Cauley, John A Robbins, Mattias Lorentzon, Igor Rudan, Thomas Illig, Claes Ohlsson, Ilja Demuth, Zoltán Kutalik, Aron S. Buchman, Jian'an Luan, Erik Ingelsson, Natalia Campos-Obando, Karol Estrada, Chan Soo Shin, Lisette Stolk, Gudmar Thorleifsson, Douglas P. Kiel, Michael N. Weedon, Lars Bertram, Fiona E. McGuigan, Ben A. Oostra, Thomas Meitinger, Mary F. Feitosa, Christian Gieger, Jean Wactawski-Wende, Yanhua Zhou, Serkalem Demissie, Najaf Amin, Anke W. Enneman, Håkan Melhus, Stuart H. Ralston, Johanna Kuusisto, Markku Laakso, Mark Walker, Tim D. Spector, Karl Michaëlsson, John-Olov Jansson, Richard L. Prince, Leif Mosekilde, Sabine Schipf, Carolina Medina-Gomez, Antti Jula, Carrie M. Nielson, Bente L. Langdahl, André G. Uitterlinden, Kay-Tee Khaw, Ruth J. F. Loos, Kristina Åkesson, Albert V. Smith, Tamara B. Harris, Cynthia A. Thomson, Karin M. A. Swart, Unnur Styrkarsdottir, Yi-Hsiang Hsu, Anne B. Newman, Murielle Bochud, M. Carola Zillikens, Alena Stančáková, Markus M. Lerch, Maria Nethander, Gregory Livshits, Dawn Waterworth, Christina M. Lill, Henry Völzke, Steven R. Cummings, Lise B. Husted, Cecilia M. Lindgren, Jaspal S. Kooner, Joshua R. Lewis, Katri Räikkönen, Linda Broer, Inês Barroso, Teemu Kuulasmaa, Jeffery R. O'Connell, Harald Grallert, William E. Kraus, Nicholas J. Wareham, Lars Lind, David Karasik, H-Erich Wichmann, Gregory J. Tranah, Mao Fu, Toby Johnson, Samuli Ripatti, Dan Mellström, Suzanne Satterfield, Jing Hua Zhao, Hyung Jin Choi, Vilmundur Gudnason, Lisette C. P. G. M. de Groot, Stephen B. Kritchevsky, Zhao Chen, Norman Klopp, Till Ittermann, Daniel S. Evans, Phillip L. De Jager, Ingrid B. Borecki, Laura M. Yerges-Armstrong, Peggy M. Cawthon, Thomas Lang, Markus Perola
Publikováno v: The American Journal of Clinical Nutrition
American Journal of Clinical Nutrition 109 (2019) 2
American Journal of Clinical Nutrition, 109(2), 276-287. American Society for Nutrition
American Journal of Clinical Nutrition, 276-287. American Society for Nutrition
STARTPAGE=276;ENDPAGE=287;ISSN=0002-9165;TITLE=American Journal of Clinical Nutrition
The American journal of clinical nutrition
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American Journal of Clinical Nutrition, vol. 109, no. 2, pp. 276-287 . https://doi.org/10.1093/ajcn/nqy272
Karasik, D, Zillikens, M C, Hsu, Y H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Swart, KMA, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chou, W C, Demuth, I, DIatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Chen, Z, Cho, N H, Choi, H J, Cummings, S R, de Groot, L C P G M, de Jager, P L, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C M, Lind, L, Lindgren, C M, Liu, Y, Livshits, G, Ljunggren, O, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gómez, C, Meitinger, T, Melhus, H, Mellstrom, D, Michaelsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Raikkonen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S, Soranzo, N, Spector, T D, Stancakova, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, NM, Vandenput, L, Vollenweider, P, Volzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', American Journal of Clinical Nutrition, pp. 276-287 .
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American Journal of Clinical Nutrition (AJCN) . https://doi.org/10.1093/ajcn/nqy272
Karasik, D, Zillikens, M C, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, D A, Bertram, L, Bochud, M, Borecki, I B, Broer, L, Buchman, A S, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, J A, Cawthon, P M, Chambers, J C, Chen, Z, Cho, N H, Choi, H J, Chou, W-C, Cummings, S R, de Groot, L C P G M, De Jager, P L, Demuth, I, Diatchenko, L, Econs, M J, Eiriksdottir, G, Enneman, A W, Eriksson, J, Eriksson, J G, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, L J, Hayward, C, Hofman, A, Homuth, G, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koller, D L, Kooner, J S, Kraus, W E, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Lerch, M M, Lewis, J R, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, R J F, Lorentzon, M, Luan, J, Luben, R N, Malkin, I, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Nethander, M, Newman, A B, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, R L, Psaty, B M, Räikkönen, K, Ralston, S H, Ripatti, S, Rivadeneira, F, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, C S, Smith, A V, Smith, S B, Soranzo, N, Spector, T D, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Thompson, P, Thomson, C A, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Uitterlinden, A G, van Duijn, C M, van Schoor, N M, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, J Wareham, N, Waterworth, D, Weedon, M N, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Yerges-Armstrong, L M, Yu, L, Zhang, W, Zhao, J H, Zhou, Y, Nielson, C M, Harris, T B, Demissie, S, Kiel, D P & Ohlsson, C 2019, ' Disentangling the genetics of lean mass ', The American journal of clinical nutrition, vol. 109, no. 2, pp. 276-287 . https://doi.org/10.1093/ajcn/nqy272
American Journal of Clinical Nutrition, 109(2), 276-278
Background: Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b768501bad6cfbb2327b96cc06a631
https://doi.org/10.1093/ajcn/nqy272
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2
Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition
Autor: Kiran Musunuru, Aldons J. Lusis, Juan Fernández-Tajes, Michelle Simon, Lydia Quaye, Peter Arner, Jordana T. Bell, Momoko Horikoshi, Avanthi Raghavan, Andrew P. Morris, Ana Viñuela, Xiao Wang, Nam Che, Ingrid Dahlman, Qiurong Ding, Mete Civelek, Matt J. Neville, Fredrik Karpe, Siddharth Sethi, Unnur Thorsteinsdottir, Calvin Pan, Kerrin S. Small, Gudmar Thorleifsson, Pei-Chien Tsai, Mark I. McCarthy, Markku Laakso, Marianne Yon, Alison Hugill, Anubha Mahajan, Anna L. Gloyn, Marijana Todorčević, Kari Stefansson, Roger D. Cox, Julia S. El-Sayed Moustafa, Alfonso Buil, Abhishek Nag, Craig A. Glastonbury
Publikováno v: Small, K S, Marijana, M, Civelek, M, El-Sayed Moustafa, J S, Wang, X, Simon, M M, Tajes, J F, Mahajan, A, Horikoshi, M, Hugill, A, Glastonbury, C A, Quaye, L, Neville, M J, Sethi, S, Yon, M, Pan, C, Che, N, Vinuela, A, Tsai, P-C, Nag, A, Buil, A, Thorleifsson, G, Raghavan, A, Ding, Q, Morris, A P, Bell, J T, Thorsteinsdottir, U, Stefansson, K, Laakso, M, Dahlman, I, Arner, P, Gloyn, A L, Musunuru, K, Lusis, A J, Cox, R D, Karpe, F & McCarthy, M I 2018, ' Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition ', Nature Genetics, vol. 50, pp. 572–580 . https://doi.org/10.1038/s41588-018-0088-x
Nature Genetics
Small, K S, Todorčević, M, Civelek, M, El-Sayed Moustafa, J S, Wang, X, Simon, M M, Fernandez-Tajes, J, Mahajan, A, Horikoshi, M, Hugill, A, Glastonbury, C A, Quaye, L, Neville, M J, Sethi, S, Yon, M, Pan, C, Che, N, Viñuela, A, Tsai, P-C, Nag, A, Buil, A, Thorleifsson, G, Raghavan, A, Ding, Q, Morris, A P, Bell, J T, Thorsteinsdottir, U, Stefansson, K, Laakso, M, Dahlman, I, Arner, P, Gloyn, A L, Musunuru, K, Lusis, A J, Cox, R D, Karpe, F & McCarthy, M I 2018, ' Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition ', Nature Genetics, vol. 50, no. 4, pp. 572-580 . https://doi.org/10.1038/s41588-018-0088-x
Individual risk of type 2 diabetes (T2D) is modified by perturbations of adipose mass, distribution and function. To investigate mechanisms responsible, we explored the molecular, cellular, and whole-body effects of T2D-associated alleles near KLF14.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2a48142a73254b78b7f405200b5b31
https://doi.org/10.1038/s41588-018-0088-x
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3
Differential effects of age and sex on insulin sensitivity and body composition in adolescent offspring of women with type 1 diabetes: results from the EPICOM study
Autor: Zuzana Lohse, Birgitte Bytoft, Kurt Højlund, Henning Beck-Nielsen, Rikke Beck Jensen, Sine Knorr, Claus Højbjerg Gravholt, Peter Oturai, Dorte Møller Jensen, Peter Damm, Tine D. Clausen
Publikováno v: Lohse, Z, Knorr, S, Bytoft, B, Clausen, T D, Jensen, R B, Oturai, P, Beck-Nielsen, H, Gravholt, C H, Damm, P, Højlund, K & Jensen, D M 2018, ' Differential effects of age and sex on insulin sensitivity and body composition in adolescent offspring of women with type 1 diabetes: results from the EPICOM study ', Diabetologia, vol. 61, no. 1, pp. 210-219 . https://doi.org/10.1007/s00125-017-4458-1
Lohse, Z, Knorr, S, Bytoft, B, Clausen, T D, Jensen, R B, Oturai, P, Beck-Nielsen, H, Gravholt, C H, Damm, P, Højlund, K & Jensen, D M 2018, ' Differential effects of age and sex on insulin sensitivity and body composition in adolescent offspring of women with type 1 diabetes : results from the EPICOM study ', Diabetologia, vol. 61, no. 1, pp. 210–219 . https://doi.org/10.1007/s00125-017-4458-1
AIMS/HYPOTHESIS: The aim of this study was to investigate the influence of age and sex on insulin sensitivity and insulin secretion in the adolescent offspring of women with type 1 diabetes, compared with the background population.METHODS: This was a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27fc7ac40d2c343619ea7bb4af1465b
https://doi.org/10.1007/s00125-017-4458-1
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4
Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study
Autor: Torben Hansen, Anette P. Gjesing, Mette Hollensted, Hans Eiberg, Claus Thorn Ekstrøm, Oluf Pedersen
Publikováno v: BMC Medical Genetics
Hollensted, M, Ekstrøm, C T, Pedersen, O, Eiberg, H, Hansen, T & Gjesing, A P 2018, ' Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood : a family-based study ', BMC Medical Genetics, vol. 19, 207, pp. 1-9 . https://doi.org/10.1186/s12881-018-0718-2
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-9 (2018)
Hollensted, M, Ekstrøm, C T, Pedersen, O, Eiberg, H, Hansen, T & Gjesing, A P 2018, ' Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood : A family-based study ', BMC Medical Genetics, vol. 19, 207 . https://doi.org/10.1186/s12881-018-0718-2
Background The genetics of fetal insulin release and/or action have been suggested to affect fetal growth, adult insulin resistance and adult body composition. The genetic correlation between body composition at birth versus glycaemic regulation and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dea10530c89f25d3e2c31d69ee2b28
http://europepmc.org/articles/PMC6278142
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5
Seven Novel Deleterious LEPR Mutations Found in Early-Onset Obesity: a ΔExon6–8 Shared by Subjects From Reunion Island, France, Suggests a Founder Effect
Autor: Martine Laville, Marc Nicolino, Hélène Huvenne, Erwan Jeannic, Amélie Viard, Béatrice Dubern, Séverine Ledoux, Patrick Tounian, Johanne Le Beyec, Jean-Marc Lacorte, Marie-Laure Frelut, Christine Poitou, Rohia Alili, Karine Clément, Patricia Pigeon Kherchiche, Dominique Pepin
Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2015, 100 (5), pp.E757-66. ⟨10.1210/jc.2015-1036⟩
International audience; CONTEXT: Infrequent mutations have been reported in the leptin receptor (LEPR) gene in humans with morbid obesity and endocrine disorders. However LEPR mutations are rarely examined in large populations from different ethnicit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be71c9e7f800a554ed5db244609606a
https://doi.org/10.1210/jc.2015-1036
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6
Genomewide meta-analysis identifies loci associated with IGF-I and IGEBP-3 levels with impact on age-related traits (vol 15, pg 811, 2016)
Autor: Teumer, A., Qi, Q., Nethander, M., Aschard, H., Bandinelli, S., Beekman, M., Berndt, S.I., Bidlingmaier, M., Broer, L., Cappola, A., Ceda, G.P., Chanock, S., Chen, M.H., Chen, T.C., Chen, Y.D.I., Chung, J., Miglianico, F.D.G., Eriksson, J., Ferrucci, L., Friedrich, N., Gnewuch, C., Goodarzi, M.O., Grarup, N., Guo, T., Hammer, E., Hayes, R.B., Hicks, A.A., Hofman, A., Houwing-Duistermaat, J.J., Hu, F., Hunter, D.J., Husemoen, L.L., Isaacs, A., Jacobs, K.B., Janssen, J.A.M.J.L., Jansson, J.O., Jehmlich, N., Johnson, S., Juul, A., Karlsson, M., Kilpelainen, T.O., Kovacs, P., Kraft, P., Li, C., Linneberg, A., Liu, Y., Loos, R.J.F., Lorentzon, M., Lu, Y., Maggio, M., Magi, R., Meigs, J., Mellstrom, D., Nauck, M., Newman, A.B., Pollak, M.N., Pramstaller, P.P., Prokopenko, I., Psaty, B.M., Reincke, M., Rimm, E.B., Rotter, J.I., Pierre, A.S., Schurmann, C., Seshadri, S., Sjogren, K., Slagboom, P.E., Strickler, H.D., Stumvoll, M., Suh, Y., Sun, Q., Zhang, C., Svensson, J., Tanaka, T., Tare, A., Tonjes, A., Uh, H.W., Duijn, C.M. van, Heemst, D. van, Vandenput, L., Vasan, R.S., Volker, U., Willems, S.M., Ohlsson, C., Wallaschofski, H., Kaplan, R.C., CHARGE Longevity Working Grp, Body Composition Genetics Consorti
Publikováno v: Aging Cell, 16(4), 898-898
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::70584002bad96adcb19834a63d2090ac
https://hdl.handle.net/1887/115287
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7
The impact of genetic variants on BMI increase during childhood versus adulthood
Autor: Paolo Piaggi, Maximilian G. Hohenadel, Yunhua L. Muller, Jonathan Krakoff, Robert L. Hanson, Leslie J. Baier, Marie S. Thearle
Publikováno v: Int J Obes (Lond)
BACKGROUND: Genetic variants that predispose individuals to obesity may have differing influences during childhood versus adulthood, and additive effects of such variants are likely to occur. Our ongoing studies to identify genetic determinants of ob
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82bf06119def218c71d70c9fa19e97c
https://pubmed.ncbi.nlm.nih.gov/27076275
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8
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits
Autor: Teumer, Alexander, Qi, Qibin, Nethander, Maria, Aschard, Hugues, Bandinelli, Stefania, Beekman, Marian, Berndt, Sonja, Bidlingmaier, Martin, Broer, Linda, Cappola, Anne, Ceda, Gian Paolo, Chanock, Stephen, Chen, Ming-Huei, Chen, Tai, Chen, Yii-Der Ida, Chung, Jonathan, Del Greco Miglianico, Fabiola, Eriksson, Joel, Ferrucci, Luigi, Friedrich, Nele, Gnewuch, Carsten, Goodarzi, Mark, Grarup, Niels, Guo, Tingwei, Hammer, Elke, Hayes, Richard, Hicks, Andrew, Hofman, Albert, Houwing-Duistermaat, Jeanine, Hu, Frank, Hunter, David, Husemoen, Lise, Isaacs, Aaron, Jacobs, Kevin, Janssen, Joop, Jansson, John-Olov, Jehmlich, Nico, Johnson, Simon, Juul, Anders, Karlsson, Magnus, Kilpelainen, Tuomas, Kovacs, Peter, Kraft, Peter, Li, Chao, Linneberg, Allan, Liu, Yongmei, Loos, Ruth, Lorentzon, Mattias, Lu, Yingchang, Maggio, Marcello, Magi, Reedik, Meigs, James, Mellström, Dan, Nauck, Matthias, Newman, Anne, Pollak, Michael, Pramstaller, Peter, Prokopenko, Inga, Psaty, Bruce, Reincke, Martin, Rimm, Eric, Rotter, Jerome, Saint Pierre, Aude, Schurmann, Claudia, Seshadri, Sudha, Sjögren, Klara, Slagboom, P Eline, Strickler, Howard, Stumvoll, Michael, Suh, Yousin, Sun, Qi, Zhang, Cuilin, Svensson, Johan, Tanaka, Toshiko, Tare, Archana, Tönjes, Anke, Uh, Hae-Won, Van Duijn, Cornelia, van Heemst, Diana, Vandenput, Liesbeth, Vasan, Ramachandran, Völker, Uwe, Willems, Sara, Ohlsson, Claes, Wallaschofski, Henri, Kaplan, Robert, Chen, Ming‐Huei, Chen, Yii‐Der Ida, Houwing‐Duistermaat, Jeanine, Jansson, John‐Olov, Slagboom, P. Eline, Uh, Hae‐Won, Heemst, Diana
Publikováno v: Aging Cell
Aging Cell, 15(5), 811-824
Aging cell, vol 15, iss 5
Aging Cell, Wiley Open Access, 2016, 15 (5), pp.811-824. ⟨10.1111/acel.12490⟩
Aging Cell, 15(5), 811-824. Wiley-Blackwell
Aging Cell, 15(5), 811-824. Wiley-Blackwell Publishing Ltd
The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF-related proteins including IGF-I and IGF-binding protein-3 (IGFBP-3) have also been implicated in risk of human diseases includ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c71dde8374929bb179f43c80584539
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9
Munc18/Syntaxin Interaction Kinetics Control Secretory Vesicle Dynamics*
Autor: Colin Rickman, Rory R. Duncan
Publikováno v: The Journal of Biological Chemistry
Rickman, C & Duncan, R R 2010, ' Munc18/Syntaxin Interaction Kinetics Control Secretory Vesicle Dynamics ', Journal of Biological Chemistry, vol. 285, no. 6, pp. 3965-3972 . https://doi.org/10.1074/jbc.M109.040402
In neuronal and hormonal release, regulated exocytosis requires an essential set of proteins: the soluble N-ethylmaleimide sensitive-factor attachment receptor proteins (SNAREs) syntaxin 1, SNAP-25, VAMP, and their regulator, Munc18. Recently, it was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069dbbee2f1066308cdfc08cdee8295c
http://europepmc.org/articles/PMC2823538
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Akademický článek
Common Genetic Factors May Play a Role in the Relationships Between Body Composition, Adipokines, and Low-Back-Pain-Related Disability.
Autor: Tarabeih, Nader1 (AUTHOR) nader@ariel.ac.il, Kalinkovich, Alexander2 (AUTHOR) alexander.kalinkovich@gmail.com, Ashkenazi, Shai1 (AUTHOR) shaias@ariel.ac.il, Shalata, Adel3 (AUTHOR) adel.shalata@gmail.com, Livshits, Gregory1,2 (AUTHOR) zviliv@ariel.ac.il
Publikováno v: Biomolecules (2218-273X). Nov2024, Vol. 14 Issue 11, p1426. 13p.
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