Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Bodo Plachter"'
Autor:
Hanno Schmidt, Niels Lemmermann, Matthias Linke, Sven-Ernö Bikár, Stefan Runkel, Susann Schweiger-Seemann, Susanne Gerber, André Michel, Thomas Hankeln, Marina Veith, Wolfgang Kohnen, Bodo Plachter
Publikováno v:
Infection Prevention in Practice, Vol 6, Iss 3, Pp 100383- (2024)
Summary: Background: During the SARS-CoV-2 pandemic, dominant viral variants were repeatedly replaced by new variants with altered properties, frequently changing the dynamics of the infection event, as well as the effectiveness of vaccines and thera
Externí odkaz:
https://doaj.org/article/7aacbde8c9f04568b116d07ff6527a72
Autor:
Nadine Krämer, Uxía Gestal Mato, Steffi Krauter, Nicole Büscher, Ahmad Afifi, Lina Herhaus, Luise Florin, Bodo Plachter, Christine Zimmermann
Publikováno v:
Viruses, Vol 16, Iss 9, p 1440 (2024)
(1) Background: Intrinsic defense mechanisms are pivotal host strategies to restrict viruses already at early stages of their infection. Here, we addressed the question of how the autophagy receptor sequestome 1 (SQSTM1/p62, hereafter referred to as
Externí odkaz:
https://doaj.org/article/6f984e54535f4c32a5d1615bd24fc5c2
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-14 (2023)
Abstract Human cytomegalovirus (HCMV) is a pathogen of high medical relevance. Subviral Dense Bodies (DB) were developed as a vaccine candidate to ameliorate the severe consequences of HCMV infection. Development of such a candidate vaccine for human
Externí odkaz:
https://doaj.org/article/6bc4e020e29c48c8b2e13f87445089ac
Publikováno v:
Viruses, Vol 15, Iss 6, p 1333 (2023)
(1) Background: Infection with human cytomegalovirus (HCMV) leads to the production and release of subviral particles, termed Dense Bodies (DB). They are enclosed by a membrane resembling the viral envelope. This membrane mediates the entrance of DBs
Externí odkaz:
https://doaj.org/article/5e636ac03244413a93f0e42c62fd686c
Publikováno v:
Wirtschaftsdienst, Vol 100, Iss 4, Pp 272-276 (2020)
Abstract The authors model the evolution of the number of confi rmed cases of COVID-19 in Germany. Their theoretical framework builds on a continuous time Markov chain with four physical states: healthy, sick, recovered or asymptomatic infected, and
Externí odkaz:
https://doaj.org/article/29cd14c409614f0c9ac0bdcfaa84d857
Publikováno v:
Cells, Vol 11, Iss 24, p 4028 (2022)
(1) Background: Cells infected with the human cytomegalovirus (HCMV) produce subviral particles, termed dense bodies (DBs), both in-vitro and in-vivo. They are released from cells, comparable to infectious virions, and are enclosed by a membrane that
Externí odkaz:
https://doaj.org/article/2e3d216afe344b7d8363f63c15b68c42
Autor:
Kerstin M. Gergely, Jürgen Podlech, Sara Becker, Kirsten Freitag, Steffi Krauter, Nicole Büscher, Rafaela Holtappels, Bodo Plachter, Matthias J. Reddehase, Niels A. W. Lemmermann
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Reactivation of latent cytomegalovirus (CMV) endangers the therapeutic success of hematopoietic cell transplantation (HCT) in tumor patients due to cytopathogenic virus spread that leads to organ manifestations of CMV disease, to interstitial pneumon
Externí odkaz:
https://doaj.org/article/003b253089d24843ab8f6ccaaba0b858
Autor:
Steffi Krauter, Nicole Büscher, Eric Bräuchle, Samira Ortega Iannazzo, Inessa Penner, Nadine Krämer, Patricia Gogesch, Simone Thomas, Marina Kreutz, Mario Dejung, Anja Freiwald, Falk Butter, Zoe Waibler, Bodo Plachter
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1326 (2022)
Human cytomegalovirus (HCMV) infection is associated with severe disease conditions either following congenital transmission of the virus or viral reactivation in immunosuppressed individuals. Consequently, the establishment of a protective vaccine i
Externí odkaz:
https://doaj.org/article/6b6f8b31f9634f6887338cdd87f2d9e4
Autor:
Sigrun Häge, Nicole Büscher, Victoria Pakulska, Friedrich Hahn, Annie Adrait, Steffi Krauter, Eva Maria Borst, Ursula Schlötzer-Schrehardt, Yohann Couté, Bodo Plachter, Manfred Marschall
Publikováno v:
Cells, Vol 10, Iss 11, p 3119 (2021)
The regulation of the nucleocytoplasmic release of herpesviral capsids is defined by the process of nuclear egress. Due to their large size, nuclear capsids are unable to traverse via nuclear pores, so that herpesviruses evolved to develop a vesicula
Externí odkaz:
https://doaj.org/article/46a30bdc73bf4f668ef99753bacfffe3
Publikováno v:
Vaccines, Vol 9, Iss 8, p 911 (2021)
A high vaccination rate of older and particularly chronically ill people against coronavirus disease-2019 (COVID-19) is likely one of the most important factors in containing the pandemic. When Germany’s vaccination campaign started on December 202
Externí odkaz:
https://doaj.org/article/057e4c07f2154cac8284f6227d87f02e