Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bodo M H Lange"'
Autor:
Zahra Maqsood, Joanne C Clark, Eleyna M Martin, Yam Fung Hilaire Cheung, Luis A Morán, Sean E T Watson, Jeremy A Pike, Ying Di, Natalie S Poulter, Alexandre Slater, Bodo M H Lange, Bernhard Nieswandt, Johannes A Eble, Mike G Tomlinson, Dylan M Owen, David Stegner, Lloyd J Bridge, Christoph Wierling, Steve P Watson
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 11, p e1010708 (2022)
The clustering of platelet glycoprotein receptors with cytosolic YxxL and YxxM motifs, including GPVI, CLEC-2 and PEAR1, triggers activation via phosphorylation of the conserved tyrosine residues and recruitment of the tandem SH2 (Src homology 2) dom
Externí odkaz:
https://doaj.org/article/4aa0aa11395e4e1d8253e586a4861727
Autor:
Paul Stapor, Leonard Schmiester, Christoph Wierling, Simon Merkt, Dilan Pathirana, Bodo M. H. Lange, Daniel Weindl, Jan Hasenauer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Ordinary differential equation (ODE) models are widely used to understand multiple processes. Here the authors show how the concept of mini-batch optimization can be transferred from the field of Deep Learning to ODE modelling.
Externí odkaz:
https://doaj.org/article/0f2289d315c2486cb8004fb1365b28cf
Publikováno v:
Cancer Informatics, Vol 2015, Iss Suppl. 4, Pp 95-103 (2015)
Externí odkaz:
https://doaj.org/article/2ab94045d2e048efae8fb1a5319a7b4f
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Every patient and every disease is different. Each patient therefore requires a personalized treatment approach. For technical reasons, a personalized approach is feasible for treatment strategies such as surgery, but not for drug-based therapy or dr
Externí odkaz:
https://doaj.org/article/39531bb7d2c24fdeb0da5c33db2465d4
Publikováno v:
Cancer Informatics, Vol 14s4 (2015)
Despite a growing body of knowledge on the mechanisms underlying the onset and progression of cancer, treatment success rates in oncology are at best modest. Current approaches use statistical methods that fail to embrace the inherent and expansive c
Externí odkaz:
https://doaj.org/article/92203b4169af4b16b46529dc658b2523
Publikováno v:
Molecular reproduction and development. 25(4)
The cytoskeleton exerts a direct effect on the function of sperm by influencing the distribution of subcellular organelles and plasma membrane molecules. We have prepared six monoclonal antibodies to Triton X-100-insoluble components of the bull sper
Autor:
Henning, Stehr, Seon-Hi J, Jang, José M, Duarte, Christoph, Wierling, Hans, Lehrach, Michael, Lappe, Bodo M H, Lange
Publikováno v:
Molecular Cancer, Vol 10, Iss 1, p 54 (2011)
Molecular Cancer
Molecular Cancer
Background Current large-scale cancer sequencing projects have identified large numbers of somatic mutations covering an increasing number of different cancer tissues and patients. However, the characterization of these mutations at the structural an